Research Centres (26996)

Clinical Trials Unit (455) Month Authors/Creators Item Type Full Text

December 2023

Reporting of Factorial Randomized Trials: Extension of the CONSORT 2010 Statement. (2023) Kahan, Brennan C; Hall, Sophie S; Beller, Elaine M; Birchenall, Megan; Chan, An-Wen; Elbourne, Diana; Little, Paul; Fletcher, John; Golub, Robert M; Goulao, Beatriz; Hopewell, Sally; Islam, Nazrul; Zwarenstein, Merrick; Juszczak, Edmund; Montgomery, Alan A

Tranexamic acid by the intramuscular or intravenous route for the prevention of postpartum haemorrhage in women at increased risk: a randomised placebo-controlled trial (I'M WOMAN). (2023) Brenner, Amy; Shakur-Still, Haleema; Chaudhri, Rizwana; Muganyizi, Projestine; Olayemi, Oladapo; Arribas, Monica; Kayani, Aasia; Javid, Kiran; Bello, Adenike; Roberts, Ian; I’M WOMAN Trial Collaborative Group

November 2023

Implementation of COVID-19 Preventive Measures and Staff Well-Being in a Sample of English Schools 2020-2021. (2023) Sundaram, Neisha; Abramsky, Tanya; Oswald, William E; Cook, Sarah; Halliday, Katherine E; Nguipdop-Djomo, Patrick; Sturgess, Joanna; Ireland, Georgina; Ladhani, Shamez N; Mangtani, Punam; Langan, Sinéad M; Hargreaves, James R; Bonell, Chris; COVID-19 Schools Infection Survey Study Group

Understanding the social and physical menstrual health environment of secondary schools in Uganda: A qualitative methods study. (2023) Ssemata, Andrew Sentoogo; Ndekezi, Denis; Kansiime, Catherine; Bakanoma, Robert; Tanton, Clare; Nelson, Kate Andrews; Hytti, Laura; Neema, Stella; Torondel, Belen; Seeley, Janet; Weiss, Helen A; MENISCUS Group

October 2023

Viability and Outcomes With Revascularization or Medical Therapy in Ischemic Ventricular Dysfunction: A Prespecified Secondary Analysis of the REVIVED-BCIS2 Trial. (2023) Perera, Divaka; Ryan, Matthew; Morgan, Holly P; Greenwood, John P; Petrie, Mark C; Dodd, Matthew; Weerackody, Roshan; O'Kane, Peter D; Masci, Pier Giorgio; Nazir, Muhummad Sohaib; Papachristidis, Alexandros; Chahal, Navtej; Khattar, Rajdeep; Ezad, Saad M; Kapetanakis, Stam; Dixon, Lana J; De Silva, Kalpa; McDiarmid, Adam K; Marber, Michael S; McDonagh, Theresa; McCann, Gerry P; Clayton, Tim C; Senior, Roxy; Chiribiri, Amedeo; REVIVED-BCIS2 Investigators

A qualitative study exploring experiences of the safetxt digital health intervention to reduce sexually transmitted infections in young people in the UK. (2023) Berendes, Sima; Gubijev, Anasztazia; French, Rebecca; Hickson, Ford Colin Ian; Free, Caroline

English headteacher perspectives on school responses to protect student and staff mental wellbeing in the later stages of the COVID-19 pandemic. (2023) McKay, Gillian; Venner, Georgia; Nguipdop-Djomo, Patrick; Mangtani, Punam; Sundaram, Neisha; Lacey, Andrea; Dawe, Fiona; Jones, Peter; Lelii, Ffion; Ladhani, Shamez; Bonell, Chris

Assessing Survey Items on Social Norms Relating to Dating and Relationship Violence and to Gender: Cognitive Interviews with Young People in England. (2023) Meiksin, Rebecca; Ponsford, Ruth; Kyegombe, Nambusi; Kohli, Anjalee; Bonell, Chris

September 2023

Contrasting principal stratum and hypothetical strategy estimands in multi-period crossover trials with incomplete data. (2023) Matthews, John NS; Bazakou, Sofia; Henderson, Robin; Sharples, Linda D picture_as_pdf

Arrhythmia and Death Following Percutaneous Revascularization in Ischemic Left Ventricular Dysfunction: Prespecified Analyses From the REVIVED-BCIS2 Trial. (2023) Perera, Divaka; Morgan, Holly P; Ryan, Matthew; Dodd, Matthew; Clayton, Tim; O'Kane, Peter D; Greenwood, John P; Walsh, Simon J; Weerackody, Roshan; McDiarmid, Adam; Amin-Youssef, George; Strange, Julian; Modi, Bhavik; Lockie, Timothy; Hogrefe, Kai; Ahmed, Fozia Z; Behan, Miles; Jenkins, Nicholas; Abdelaal, Eltigani; Anderson, Michelle; Watkins, Stuart; Evans, Richard; Rinaldi, Christopher A; Petrie, Mark C; REVIVED-BCIS2 Investigators

winratiotest: A command for implementing the win ratio and stratified win ratio in Stata. (2023) Gregson, John; Ferreira, João Pedro; Collier, Tim

August 2023

Understanding experiences of potential harm among MSM (cis and trans) using HIV self-testing in the SELPHI randomised controlled trial in England and Wales: a mixed-methods study. (2023) Witzel, T Charles; Nicholls, Emily Jay; McCabe, Leanne; Weatherburn, Peter; McCormack, Sheena; Bonell, Christopher; Gafos, Mitzy; Lampe, Fiona C; Speakman, Andrew; Dunn, David; Ward, Denise; Phillips, Andrew N; Pebody, Roger; Gabriel, Michelle M; Collaco-Moraes, Yolanda; Rodger, Alison J; Burns, Fiona M

Using Habermas’ theory of communicative action to transform sociological analyses of evidence-based policy. (2023) Bonell, Chris; Melendez-Torres, GJ

Whole-school interventions promoting student commitment to school to prevent substance use and violence: a systematic review. (2023) Melendez-Torres, GJ; Ponsford, R; Falconer, J; Bonell, C

July 2023

Association of cannabis, cannabidiol and synthetic cannabinoid use with mental health in UK adolescents. (2023) Hotham, James; Cannings-John, Rebecca; Moore, Laurence; Hawkins, Jemma; Bonell, Chris; Hickman, Matthew; Zammit, Stanley; Hines, Lindsey A; Adara, Linda; Townson, Julia; White, James

Mobile phone-based interventions for improving contraception use. (2023) Perinpanathan, Tanaraj; Maiya, Shilpa; van Velthoven, Michelle Helena Hmmt; Nguyen, Amy T; Free, Caroline; Smith, Chris

"Figuring stuff out myself" - a qualitative study on maternal vaccination in socially and ethnically diverse areas in England. (2023) Berendes, Sima; Mounier-Jack, Sandra; Ojo-Aromokudu, Oyinkansola; Ivory, Alice; Tucker, Joseph D; Larson, Heidi J; Free, Caroline

Statistical analysis plan for a cluster randomised trial in Madhya Pradesh, India: support to rural India's public education system and impact on numeracy and literacy scores (STRIPES2). (2023) Keddie, Suzanne; Fazzio, Ila; Shivalli, Siddharudha; Magill, Nicholas; Elbourne, Diana; Sharma, Dropti; Shekhawat, Sajjan Singh; Banerji, Rukmini; Karnati, Sridevi; Reddy, Harshavardhan; Eble, Alex; Boone, Peter; Frost, Chris

June 2023

Maternal anaemia and the risk of postpartum haemorrhage: a cohort analysis of data from the WOMAN-2 trial. (2023) WOMAN-2 trial collaborators. Electronic address: woman2@lshtm.ac; WOMAN-2 trial collaborators

Defining Peri-Operative Myocardial Injury during Cardiac Surgery Using High-Sensitivity Troponin T. (2023) Sharma, Vikram; Zheng, Huili; Candilio, Luciano; Nicholas, Jennifer M; Clayton, Tim; Yellon, Derek M; Bulluck, Heerajnarain; Hausenloy, Derek J

Coinfections of malaria and sexually transmitted and reproductive tract infections in pregnancy in sub-Saharan Africa: a systematic review and individual participant data meta-analysis protocol. (2023) Sorano, Sumire; Gore-Langton, Georgia; Opondo, Charles; Smith, Chris; Matsui, Mitsuaki; Chaponda, Enesia Banda; Chandramohan, Daniel; Chico, R Matthew

Are school-based interventions to prevent dating and relationship violence and gender-based violence equally effective for all students? Systematic review and equity analysis of moderation analyses in randomised trials. (2023) Melendez-Torres, GJ; Bonell, Chris; Shaw, Naomi; Orr, Noreen; Chollet, Annah; Rizzo, Andrew; Rigby, Emma; Hagell, Ann; Young, Honor; Berry, Vashti; Humphreys, David K; Farmer, Caroline

Re-orientating systematic reviews to rigorously examine what works, for whom and how: Example of a realist systematic review of school-based prevention of dating and gender violence. (2023) Bonell, Chris; Taylor, Bruce; Berry, Vashti; Filho, Sidnei R Priolo; Rizzo, Andrew; Farmer, Caroline; Hagell, Ann; Young, Honor; Orr, Noreen; Shaw, Naomi; Chollet, Annah; Kiff, Fraizer; Rigby, Emma; Melendez-Torres, GJ

Approaches to consent in public health research in secondary schools. (2023) Bonell, Chris; Humphrey, Neil; Singh, Ilina; Viner, Russell M; Ford, Tamsin

Process and costs for readiness to safely implement immediate kangaroo mother care: a mixed methods evaluation from the OMWaNA trial at five hospitals in Uganda. (2023) Medvedev, Melissa M; Tumukunde, Victor; Kirabo-Nagemi, Charity; Greco, Giulia; Mambule, Ivan; Katumba, Kenneth; Waiswa, Peter; Tann, Cally J; Elbourne, Diana; Allen, Elizabeth; Ekirapa-Kiracho, Elizabeth; Pitt, Catherine; Lawn, Joy E

Student-reported relationships and sex education coverage and knowledge among a diverse population of early adolescents: a cross-sectional survey of students in England. (2023) Melendez-Torres, GJ; Ponsford, Ruth; Meiksin, Rebecca; Tilouche, Nerissa; Sundaram, Neisha; Sturgess, Joanna; Allen, Elizabeth; Lohan, Maria; Young, Honor; Hadley, Alison; Campbell, Rona; Bonell, Chris

Effectiveness of the GRACE risk score on the management and outcome of patients hospitalised with non-ST elevation acute coronary syndrome (UKGRIS): a parallel-group cluster-randomised registry-based controlled trial. (2023) Gale, Chris; Stocken, Deborah; Aktaa, Suleman; Reynolds, Catherine; Gilberts, Rachael; Brieger, David; Carruthers, Kathryn; Chew, Derek; Goodman, Shaun; Fernandez, Catherine; Sharples, Linda; Yan, Andrew; Fox, Keith

May 2023

Exploring views of members of the public and policymakers on the acceptability of population level dietary and active-travel policies: a qualitative study. (2023) Toumpakari, Z; Valerino-Perea, S; Willis, K; Adams, J; White, M; Vasiljevic, M; Ternent, L; Brown, J; Kelly, MP; Bonell, C; Cummins, S; Majeed, A; Anderson, S; Robinson, T; Araujo-Soares, V; Watson, J; Soulsby, I; Green, D; Sniehotta, FF; Jago, R

Factors affecting women's participation in cardiovascular research: a scoping review. (2023) Matthews, Stacey; Cook, Samantha; Clayton, Tim; Murray, Sarah; Wynne, Rochelle; Sanders, Julie

April 2023

Biolimus-eluting vs. other limus-eluting stents in NSTE-ACS: A pooled analysis of GLASSY and TWILIGHT. (2023) Spirito, Alessandro; Valgimigli, Marco; Cao, Davide; Baber, Usman; Mehta, Shamir R; Gibson, C Michael; Steg, Gabriel P; Sharma, Samin K; Goel, Ridhima; Huber, Kurt; Kunadian, Vijay; Escaned, Javier; Franzone, Anna; Yaling, Han; Collier, Timothy; Kaul, Upendra; Kornowski, Ran; Krucoff, Mitchell; Moliterno, David; Sartori, Samantha; Owen, Ruth; Zhang, Zhongjie; Dangas, George D; Kastrati, Adnan; Angiolillo, Dominick J; Cohen, David J; Vranckx, Pascal; Windecker, Stephan; Pocock, Stuart; Mehran, Roxana

The use of mediation analysis in evaluation of complex health interventions. (2023) DiLiberto, Deborah D; Opondo, Charles; Staedke, Sarah G; Chandler, Clare IR; Allen, Elizabeth

The win ratio method in heart failure trials: lessons learnt from EMPULSE. (2023) Pocock, Stuart J; Ferreira, João Pedro; Collier, Timothy J; Angermann, Christiane E; Biegus, Jan; Collins, Sean P; Kosiborod, Mikhail; Nassif, Michael E; Ponikowski, Piotr; Psotka, Mitchell A; Teerlink, John R; Tromp, Jasper; Gregson, John; Blatchford, Jonathan P; Zeller, Cordula; Voors, Adriaan A

Alternative routes for tranexamic acid treatment in obstetric bleeding (WOMAN-PharmacoTXA trial): a randomised trial and pharmacological study in caesarean section births. (2023) Shakur-Still, Haleema; Roberts, Ian; Grassin-Delyle, Stanislas; Chaudhri, Rizwana; Geer, Amber; Arribas, Monica; Lamy, Elodie; Mansukhani, Raoul; Lubeya, Mwansa Ketty; Javaid, Kiran; Kayani, Aasia; Israr, Naila; Mazhar, Syeda Batool; Urien, Saïk; Bouazza, Naïm; Foissac, Frantz; Prowse, Danielle; Carrington, Laura; Barrow, Collette; Onandia, Julio Gil; Balogun, Eni

March 2023

Effect of Spironolactone on QRS Duration in Patients at Risk for Heart Failure (from the HOMAGE Trial). (2023) Ferreira, João Pedro; Cleland, John GF; Girerd, Nicolas; Pellicori, Pierpaolo; Hazebroek, Mark R; Verdonschot, Job; Collier, Timothy J; Petutschnigg, Johannes; Clark, Andrew L; Staessen, Jan A; Heymans, Stephane; Rossignol, Patrick; Zannad, Faiez

Post-malnutrition growth and its associations with child survival and non-communicable disease risk: a secondary analysis of the Malawi 'ChroSAM' cohort. (2023) Lelijveld, Natasha; Cox, Sioned; Anujuo, Kenneth; Amoah, Abena S; Opondo, Charles; Cole, Tim J; Wells, Jonathan Ck; Thompson, Debbie; McKenzie, Kimberley; Abera, Mubarek; Berhane, Melkamu; Kerac, Marko; CHANGE study collaborators group

Prevalence of Plasmodium falciparum haplotypes associated with resistance to sulfadoxine-pyrimethamine and amodiaquine before and after upscaling of seasonal malaria chemoprevention in seven African countries: a genomic surveillance study. (2023) Beshir, Khalid B; Muwanguzi, Julian; Nader, Johanna; Mansukhani, Raoul; Traore, Aliou; Gamougam, Kadidja; Ceesay, Sainey; Bazie, Thomas; Kolie, Fassou; Lamine, Mahaman M; Cairns, Matt; Snell, Paul; Scott, Susana; Diallo, Abdoulaye; Merle, Corinne S; NDiaye, Jean Louis; Razafindralambo, Lanto; Moroso, Diego; Ouedraogo, Jean-Bosco; Zongo, Issaka; Kessely, Hamit; Doumagoum, Daugla; Bojang, Kalifa; Ceesay, Serign; Loua, Kovana; Maiga, Hamma; Dicko, Alassane; Sagara, Issaka; Laminou, Ibrahim M; Ogboi, Sonny Johnbull; Eloike, Tony; Milligan, Paul; Sutherland, Colin J

Safety and efficacy of ticagrelor monotherapy according to drug-eluting stent type: the TWILIGHT-STENT study. (2023) Dangas, George; Baber, Usman; Sharma, Samin; Giustino, Gennaro; Sartori, Samantha; Nicolas, Johny; Goel, Ridhima; Mehta, Shamir; Cohen, David; Angiolillo, Dominick J; Zhang, Zhongjie; Camaj, Anton; Cao, Davide; Briguori, Carlo; Dudek, Dariusz; Escaned, Javier; Huber, Kurt; Collier, Timothy; Kornowski, Ran; Kunadian, Vijay; Moliterno, David J; Ohman, E Magnus; Weisz, Giora; Gil, Robert; Krucoff, Mitchell W; Kaul, Upendra; Oldroyd, Keith G; Sardella, Gennaro; Shlofmitz, Richard; Witzenbichler, Bernhard; Kastrati, Adnan; Han, Ya-Ling; Steg, Philippe Gabriel; Pocock, Stuart; Gibson, C Michael; Mehran, Roxana

Contraceptive use and pregnancy planning in Britain during the first year of the COVID-19 pandemic: findings from a large, quasi-representative survey (Natsal-COVID). (2023) Baxter, Andrew J; Geary, Rebecca S; Dema, Emily; Bosó Pérez, Raquel; Riddell, Julie; Willis, Malachi; Conolly, Anne; Oakley, Laura L; Copas, Andrew J; Gibbs, Jo; Bonell, Christopher; Sonnenberg, Pam; Mercer, Catherine H; Clifton, Soazig; Field, Nigel; Mitchell, Kirsten

February 2023

Buruli-RifDACC: Evaluation of the efficacy and cost-effectiveness of high-dose versus standard-dose rifampicin on outcomes in Mycobacteriumulcerans disease, a protocol for a randomised controlled trial in Ghana. (2023) Amoako, Yaw Ampem; Agbanyo, Abigail; Novignon, Jacob; Owusu, Lucy; Tuffour, Joseph; Asante-Poku, Adwoa; Hailemichael, Yohannes; Mosweu, Iris; Canter, Ruth; Opondo, Charles; Allen, Elizabeth; Pitt, Catherine; Yeboah-Manu, Dorothy; Walker, Stephen L; Marks, Michael; Phillips, Richard Odame; SHARP collaboration

Social Norms About Dating and Relationship Violence and Gender Among Adolescents: Systematic Review of Measures Used in Dating and Relationship Violence Research. (2023) Meiksin, Rebecca; Bonell, Chris; Bhatia, Amiya; Melendez-Torres, GJ; Kyegombe, Nambusi; Kohli, Anjalee

Association Between Gender Minority Status and Mental Health in High School Students. (2023) White, James; Moore, Laurence; Cannings-John, Rebecca; Hawkins, Jemma; Bonell, Chris; Hickman, Matthew; Zammit, Stanley; Adara, Linda

Tranexamic acid for gastrointestinal bleeding: can a reduction in the risk of death be discounted? A systematic review and meta-analysis of individual patient data from 64 724 bleeding patients. (2023) Ker, Katharine; Mansukhani, Raoul; Shakur-Still, Haleema; Arribas, Monica; Beaumont, Danielle; Roberts, Ian

January 2023

Ticagrelor with or without aspirin in high-risk patients with anaemia undergoing percutaneous coronary intervention: a subgroup analysis of the TWILIGHT trial. (2023) Spirito, Alessandro; Kastrati, Adnan; Cao, Davide; Baber, Usman; Sartori, Samantha; Angiolillo, Dominick J; Briguori, Carlo; Cohen, David J; Dangas, George; Dudek, Dariusz; Escaned, Javier; Gibson, C Michael; Zhang, Zhongjie; Huber, Kurt; Kaul, Upendra; Kornowski, Ran; Kunadian, Vijay; Han, Ya-Ling; Mehta, Shamir R; Sardella, Gennaro; Sharma, Samin; Shlofmitz, Richard A; Vogel, Birgit; Collier, Timothy; Pocock, Stuart; Mehran, Roxana

Involving men and boys in family planning: A systematic review of the effective components and characteristics of complex interventions in low- and middle-income countries. (2023) Aventin, Áine; Robinson, Martin; Hanratty, Jennifer; Keenan, Ciara; Hamilton, Jayne; McAteer, Eimear Ruane; Tomlinson, Mark; Clarke, Mike; Okonofua, Friday; Bonell, Chris; Lohan, Maria

Risk factors for SARS-CoV-2 infection in primary and secondary school students and staff in England in the 2020/2021 school year: a longitudinal study. (2023) Nguipdop-Djomo, Patrick; Oswald, William E; Halliday, Katherine E; Cook, Sarah; Sturgess, Joanna; Sundaram, Neisha; Warren-Gash, Charlotte; Fine, Paul Em; Glynn, Judith; Allen, Elizabeth; Clark, Taane G; Ford, Benjamin; Judd, Alison; Ireland, Georgina; Poh, John; Bonell, Chris; Dawe, Fiona; Rourke, Emma; Diamond, Ian; Ladhani, Shamez N; Langan, Sinéad M; Hargreaves, James; Mangtani, Punam; COVID-19 Schools Infection Survey Study Group

Testing and refining middle-range theory in evaluations of public-health interventions: evidence from recent systematic reviews and trials. (2023) Bonell, Chris; Ponsford, Ruth; Meiksin, Rebecca; Melendez-Torres, GJ

Behavioural intervention to reduce sexually transmitted infections in people aged 16–24 years in the UK: the safetxt RCT. (2023) Free, Caroline; Palmer, Melissa J; Potter, Kimberley; McCarthy, Ona L; Jerome, Lauren; Berendes, Sima; Gubijev, Anasztazia; Knight, Megan; Jamal, Zahra; Dhaliwal, Farandeep; Carpenter, James R; Morris, Tim P; Edwards, Phil; French, Rebecca; Macgregor, Louis; Turner, Katy ME; Baraitser, Paula; Hickson, Ford CI; Wellings, Kaye; Roberts, Ian; Bailey, Julia V; Hart, Graham; Michie, Susan; Clayton, Tim; Devries, Karen