Items where Research Centre is "Clinical Trials Unit"
Research Centres (26996)
Clinical Trials Unit (455)
Number of items: 55.
May 2021
Development of a patient reported outcome questionnaire to measure the impact of postpartum blood loss in women with moderate and severe anaemia: A study using a multi-faceted approach. (2019)
Miller, Lori; Chaudhri, Shahana; Beaumont, Danielle; Kayani, Aasia; Javid, Kiran; Chaudhri, Rizwana; Edwards, Phil; Brenner, Amy; Roberts, Ian; Shakur-Still, Haleema
January 2020
Operationalising kangaroo Mother care before stabilisation amongst low birth Weight Neonates in Africa (OMWaNA): protocol for a randomised controlled trial to examine mortality impact in Uganda. (2019)
Medvedev, Melissa M; Tumukunde, Victor; Mambule, Ivan; Tann, Cally J; Waiswa, Peter; Canter, Ruth R; Hansen, Christian H; Ekirapa-Kiracho, Elizabeth; Katumba, Kenneth; Pitt, Catherine; Greco, Giulia; Brotherton, Helen; Elbourne, Diana; Seeley, Janet; Nyirenda, Moffat; Allen, Elizabeth; Lawn, Joy E
December 2019
Can selenium deficiency in Malawi be alleviated through consumption of agro-biofortified maize flour? Study protocol for a randomised, double-blind, controlled trial. (2019)
Joy, Edward JM; Kalimbira, Alexander A; Gashu, Dawd; Ferguson, Elaine L; Sturgess, Joanna; Dangour, Alan D; Banda, Leonard; Chiutsi-Phiri, Gabriella; Bailey, Elizabeth H; Langley-Evans, Simon C; Lark, R Murray; Millar, Kate; Young, Scott D; Matandika, Limbanazo; Mfutso-Bengo, Joseph; Phuka, John C; Phiri, Felix P; Gondwe, Jellita; Ander, E Louise; Lowe, Nicola M; Nalivata, Patson C; Broadley, Martin R; Allen, Elizabeth
Using Digital Technology for Sexual and Reproductive Health: Are Programs Adequately Considering Risk? (2019)
Bacchus, Loraine J; Reiss, Kate; Church, Kathryn; Colombini, Manuela; Pearson, Erin; Naved, Ruchira; Smith, Chris; Andersen, Kathryn; Free, Caroline
HIV self-testing intervention experiences and kit usability: results from a qualitative study among men who have sex with men in the SELPHI (Self-Testing Public Health Intervention) randomized controlled trial in England and Wales. (2019)
Witzel, TC; Bourne, A; Burns, FM; Rodger, AJ; McCabe, L; Gabriel, MM; Gafos, M; Ward, D; Collaco-Moraes, Y; Dunn, DT; Speakman, A; Bonell, C; Pebody, R; Lampe, FC; Harbottle, J; Phillips, AN; McCormack, S; Weatherburn, P
Evaluation of the efficacy and safety of text messages targeting adherence to cardiovascular medications in secondary prevention: the txt2heart Colombia randomised controlled trial protocol. (2019)
Bermon, Anderson; Uribe-Rodríguez, Ana Fernanda; Pérez-Rivero, Paula Fernanda; Prieto-Merino, David; Cáceres Rivera, Diana Isabel; Guio, Elizabeth; Atkins, Louise; Horne, Robert; Murray, Elizabeth; Serrano Díaz, Norma Cecilia; Free, Caroline; Perel, Pablo; Casas, Juan P
A systematic review and meta-analysis in the effectiveness of mobile phone interventions used to improve adherence to antiretroviral therapy in HIV infection. (2019)
Shah, Reshma; Watson, Julie; Free, Caroline
Irbesartan in Marfan syndrome (AIMS): a double-blind, placebo-controlled randomised trial. (2019)
Mullen, Michael; Jin, Xu Yu; Child, Anne; Stuart, A Graham; Dodd, Matthew; Aragon-Martin, José Antonio; Gaze, David; Kiotsekoglou, Anatoli; Yuan, Li; Hu, Jiangting; Foley, Claire; Van Dyck, Laura; Knight, Rosemary; Clayton, Tim; Swan, Lorna; Thomson, John DR; Erdem, Guliz; Crossman, David; Flather, Marcus; AIMS Investigators
November 2019
A nested randomised trial of the effect of tranexamic acid on intracranial haemorrhage and infarction in traumatic brain injury (CRASH-3 trial intracranial bleeding mechanistic study): Statistical analysis plan. (2019)
Mahmood, Abda; Roberts, Ian; Shakur-Still, Haleema
The clustering of risk behaviours in adolescence and health consequences in middle age. (2019)
Akasaki, Mifuyu; Ploubidis, George B; Dodgeon, Brian; Bonell, Chris P
Effects of tranexamic acid on death, disability, vascular occlusive events and other morbidities in patients with acute traumatic brain injury (CRASH-3): a randomised, placebo-controlled trial. (2019)
CRASH-3 trial collaborators
Yoga and Cardiovascular Health Trial (YACHT): a UK-based randomised mechanistic study of a yoga intervention plus usual care versus usual care alone following an acute coronary event. (2019)
Tillin, Therese; Tuson, Claire; Sowa, Barbara; Chattopadhyay, Kaushik; Sattar, Naveed; Welsh, Paul; Roberts, Ian; Ebrahim, Shah; Kinra, Sanjay; Hughes, A; Chaturvedi, Nishi
Modifying the secondary school environment to reduce bullying and aggression: the INCLUSIVE cluster RCT. (2019)
Bonell, Chris; Allen, Elizabeth; Warren, Emily; McGowan, Jennifer; Bevilacqua, Leonardo; Jamal, Farah; Sadique, Zia; Legood, Rosa; Wiggins, Meg; Opondo, Charles; Mathiot, Anne; Sturgess, Joanna; Paparini, Sara; Fletcher, Adam; Perry, Miranda; West, Grace; Tancred, Tara; Scott, Stephen; Elbourne, Diana; Christie, Deborah; Bond, Lyndal; Viner, Russell M
The relative importance of perceived substance misuse use by different peers on smoking, alcohol and illicit drug use in adolescence. (2019)
Er, Vanessa; Campbell, Rona; Hickman, Matthew; Bonell, Chris; Moore, Laurence; White, James
October 2019
Reducing research waste by promoting informed responses to invitations to participate in clinical trials. (2019)
Elbourne, Diana
Reducing research waste by promoting informed responses to invitations to participate in clinical trials. (2019)
Gillies, Katie; Chalmers, Iain; Glasziou, Paul; Elbourne, Diana; Elliott, Jim; Treweek, Shaun
Evaluation of the effects of sodium-glucose co-transporter 2 inhibition with empagliflozin on morbidity and mortality in patients with chronic heart failure and a preserved ejection fraction: rationale for and design of the EMPEROR-Preserved Trial. (2019)
Anker, Stefan D; Butler, Javed; Filippatos, Gerasimos S; Jamal, Waheed; Salsali, Afshin; Schnee, Janet; Kimura, Karen; Zeller, Cordula; George, Jyothis; Brueckmann, Martina; Zannad, Faiez; Packer, Milton; EMPEROR-Preserved Trial Committees and Investigators
Role theory of schools and adolescent health. (2019)
Bonell, Chris; Blakemore, Sarah-Jayne; Fletcher, Adam; Patton, George
Reporting of randomized factorial trials was frequently inadequate. (2019)
Kahan, Brennan C; Tsui, Michael; Jairath, Vipul; Scott, Anna Mae; Altman, Douglas G; Beller, Elaine; Elbourne, Diana
September 2019
Ticagrelor with or without Aspirin in High-Risk Patients after PCI. (2019)
Mehran, Roxana; Baber, Usman; Sharma, Samin K; Cohen, David J; Angiolillo, Dominick J; Briguori, Carlo; Cha, Jin Y; Collier, Timothy; Dangas, George; Dudek, Dariusz; Džavík, Vladimír; Escaned, Javier; Gil, Robert; Gurbel, Paul; Hamm, Christian W; Henry, Timothy; Huber, Kurt; Kastrati, Adnan; Kaul, Upendra; Kornowski, Ran; Krucoff, Mitchell; Kunadian, Vijay; Marx, Steven O; Mehta, Shamir R; Moliterno, David; Ohman, E Magnus; Oldroyd, Keith; Sardella, Gennaro; Sartori, Samantha; Shlofmitz, Richard; Steg, P Gabriel; Weisz, Giora; Witzenbichler, Bernhard; Han, Ya-Ling; Pocock, Stuart; Gibson, C Michael
Interventions integrating health and academic education in schools to prevent substance misuse and violence: a systematic review. (2019)
Tancred, Tara; Melendez-Torres, GJ; Paparini, Sara; Fletcher, Adam; Stansfield, Claire; Thomas, James; Campbell, Rona; Taylor, Suzanne; Bonell, Chris
Effect of remote ischaemic conditioning on clinical outcomes in patients with acute myocardial infarction (CONDI-2/ERIC-PPCI): a single-blind randomised controlled trial. (2019)
Hausenloy, Derek J; Kharbanda, Rajesh K; Møller, Ulla Kristine; Ramlall, Manish; Aarøe, Jens; Butler, Robert; Bulluck, Heerajnarain; Clayton, Tim; Dana, Ali; Dodd, Matthew; Engstrom, Thomas; Evans, Richard; Lassen, Jens Flensted; Christensen, Erika Frischknecht; Garcia-Ruiz, José Manuel; Gorog, Diana A; Hjort, Jakob; Houghton, Richard F; Ibanez, Borja; Knight, Rosemary; Lippert, Freddy K; Lønborg, Jacob T; Maeng, Michael; Milasinovic, Dejan; More, Ranjit; Nicholas, Jennifer M; Jensen, Lisette Okkels; Perkins, Alexander; Radovanovic, Nebojsa; Rakhit, Roby D; Ravkilde, Jan; Ryding, Alisdair D; Schmidt, Michael R; Riddervold, Ingunn Skogstad; Sørensen, Henrik Toft; Stankovic, Goran; Varma, Madhusudhan; Webb, Ian; Terkelsen, Christian Juhl; Greenwood, John P; Yellon, Derek M; Bøtker, Hans Erik; CONDI-2/ERIC-PPCI Investigators
Evaluation of the impact of the GRACE risk score on the management and outcome of patients hospitalised with non-ST elevation acute coronary syndrome in the UK: protocol of the UKGRIS cluster-randomised registry-based trial. (2019)
Everett, Colin C; Fox, Keith Aa; Reynolds, Catherine; Fernandez, Catherine; Sharples, Linda; Stocken, Deborah D; Carruthers, Kathryn; Hemingway, Harry; Yan, Andrew T; Goodman, Shaun G; Brieger, David; Chew, Derek P; Gale, Chris P
August 2019
Pilot phase of an internet-based RCT of HIVST targeting MSM and transgender people in England and Wales: advertising strategies and acceptability of the intervention. (2019)
Witzel, T Charles; Gabriel, Michelle M; McCabe, Leanne; Weatherburn, Peter; Gafos, Mitzy; Speakman, Andrew; Pebody, Roger; Burns, Fiona M; Bonell, Chris; Lampe, Fiona C; Dunn, David T; Ward, Denise; Harbottle, Justin; Phillips, Andrew N; McCormack, Sheena; Rodger, Alison J
Understanding the unintended consequences of public health policies: the views of policymakers and evaluators. (2019)
Oliver, Kathryn; Lorenc, Theo; Tinkler, Jane; Bonell, Chris
Secondary analysis of the WOMAN trial to explore the risk of sepsis after invasive treatments for postpartum hemorrhage. (2019)
Cornelissen, Laura; Woodd, Susannah; Shakur-Still, Haleema; Fawole, Bukola; Noor, Shehla; Etuk, Saturday; Akintan, Adesina Lawrence; Chaudhri, Rizwana; Roberts, Ian
Early remote ischaemic preconditioning leads to sustained improvement in allograft function after live donor kidney transplantation: long-term outcomes in the REnal Protection Against Ischaemia-Reperfusion in transplantation (REPAIR) randomised trial. (2019)
Veighey, Kristin V; Nicholas, Jennifer M; Clayton, Tim; Knight, Rosemary; Robertson, Steven; Dalton, Neil; Harber, Mark; Watson, Christopher JE; De Fijter, Johan W; Loukogeorgakis, Stavros; MacAllister, Raymond
July 2019
Tranexamic acid for acute gastrointestinal bleeding (the HALT-IT trial): statistical analysis plan for an international, randomised, double-blind, placebo-controlled trial. (2019)
Brenner, Amy; Afolabi, Adefemi; Ahmad, Syed Masroor; Arribas, Monica; Chaudhri, Rizwana; Coats, Timothy; Cuzick, Jack; Gilmore, Ian; Hawkey, Christopher; Jairath, Vipul; Javaid, Kiran; Kayani, Aasia; Mutti, Muttiullah; Nadeem, Muhammad Arif; Shakur-Still, Haleema; Stanworth, Simon; Veitch, Andrew; Roberts, Ian; HALT-IT Trial Collaborators
Evaluation of the effect of sodium-glucose co-transporter 2 inhibition with empagliflozin on morbidity and mortality of patients with chronic heart failure and a reduced ejection fraction: rationale for and design of the EMPEROR-Reduced trial. (2019)
Packer, Milton; Butler, Javed; Filippatos, Gerasimos S; Jamal, Waheed; Salsali, Afshin; Schnee, Janet; Kimura, Karen; Zeller, Cordula; George, Jyothis; Brueckmann, Martina; Anker, Stefan D; Zannad, Faiez; EMPEROR-Reduced Trial Committees and Investigators
Reference-based sensitivity analysis for time-to-event data. (2019)
Atkinson, Andrew; Kenward, Michael G; Clayton, Tim; Carpenter, James R
Action groups as a participative strategy for leading whole‐school health promotion: Results on implementation from the<scp>INCLUSIVE</scp>trial in English secondary schools. (2019)
Warren, Emily; Bevilacqua, Leonardo; Opondo, Charles; Allen, Elizabeth; Mathiot, Anne; West, Grace; Jamal, Farah; Viner, Russell; Bonell, Chris
Formative mixed-method multicase study research to inform the development of a safer sex and healthy relationships intervention in further education (FE) settings: the SaFE Project. (2019)
Young, Honor; Turney, Catherine; White, James; Lewis, Ruth; Bonell, Christopher
Tranexamic acid to improve functional status in adults with spontaneous intracerebral haemorrhage: the TICH-2 RCT. (2019)
Sprigg, Nikola; Flaherty, Katie; Appleton, Jason P; Al-Shahi Salman, Rustam; Bereczki, Daniel; Beridze, Maia; Ciccone, Alfonso; Collins, Ronan; Dineen, Robert A; Duley, Lelia; Egea-Guerrero, Juan José; England, Timothy J; Karlinski, Michal; Krishnan, Kailash; Laska, Ann Charlotte; Law, Zhe Kang; Ovesen, Christian; Ozturk, Serefnur; Pocock, Stuart J; Roberts, Ian; Robinson, Thompson G; Roffe, Christine; Peters, Nils; Scutt, Polly; Thanabalan, Jegan; Werring, David; Whynes, David; Woodhouse, Lisa; Bath, Philip M
Joint contribution of socioeconomic circumstances and ethnic group to variations in preterm birth, neonatal mortality and infant mortality in England and Wales: a population-based retrospective cohort study using routine data from 2006 to 2012. (2019)
Opondo, Charles; Gray, Ron; Hollowell, Jennifer; Li, Yangmei; Kurinczuk, Jennifer J; Quigley, Maria A
CONSORT 2010 statement: extension to randomised crossover trials. (2019)
Dwan, Kerry; Li, Tianjing; Altman, Douglas G; Elbourne, Diana
June 2019
Evaluation of the impact of the GRACE risk score on the management and outcome of patients hospitalised with non-ST elevation acute coronary syndrome: protocol of the UKGRIS cluster-randomised registry-based trial. (2019)
Everett, Colin; Fox, Keith; Reynolds, Catherine; Fernandez, Catherine; Sharples, Linda; Stocken, Deborah; Carruthers, Kathryn; Hemmingway, Harry; Yan, Andrew; Goodman, Shaun; Brieger, David; Chew, Derek; Gale, Chris
Invariant Natural Killer T-cell Dynamics in Human Immunodeficiency Virus-associated Tuberculosis. (2019)
Walker, Naomi F; Opondo, Charles; Meintjes, Graeme; Jhilmeet, Nishtha; Friedland, Jon S; Elkington, Paul T; Wilkinson, Robert J; Wilkinson, Katalin A
The effectiveness and safety of anti-fibrinolytics in patients with acute intracranial haemorrhage: statistical analysis plan for an individual patient data meta-analysis. (2019)
Ker, Katharine; Prieto-Merino, David; Sprigg, Nikola; Mahmood, Abda; Bath, Philip; Kang Law, Zhe; Flaherty, Katie; Roberts, Ian
Does internet-accessed STI (e-STI) testing increase testing uptake for chlamydia and other STIs among a young population who have never tested? Secondary analyses of data from a randomised controlled trial. (2019)
Wilson, Emma; Leyrat, Clémence; Baraitser, Paula; Free, Caroline
Trial management: we need a cadre of high-class triallists to deliver the answers that patients need. (2019)
Beaumont, Danielle; Arribas, Monica; Frimley, Lauren; Balogun, Eni; Roberts, Ian; Shakur-Still, Haleema
May 2019
Prognostic model for traumatic death due to bleeding: cross-sectional international study. (2019)
Ageron, Francois-Xavier; Gayet-Ageron, Angele; Steyerberg, Ewout; Bouzat, Pierre; Roberts, Ian
Identifying postnatal depression: Comparison of a self-reported depression item with Edinburgh Postnatal Depression Scale scores at three months postpartum. (2019)
Fellmeth, Gracia; Opondo, Charles; Henderson, Jane; Redshaw, Maggie; Mcneill, Jenny; Lynn, Fiona; Alderdice, Fiona
Characteristics and contraceptive outcomes of women seeking medical or surgical abortion in reproductive health clinics in Cambodia. (2019)
Smith, Chris; Scott, Rachel H; Free, Caroline; Edwards, Tansy
Effects of Interventions Addressing School Environments or Educational Assets on Adolescent Sexual Health: Systematic Review and Meta-analysis. (2019)
Peterson, Amy J; Donze, Melissa; Allen, Elizabeth; Bonell, Chris
April 2019
Tranexamic acid for post-partum haemorrhage: What, who and when. (2019)
Brenner, Amy; Ker, Katharine; Shakur-Still, Haleema; Roberts, Ian
Tranexamic acid for acute gastrointestinal bleeding (The HALT-IT trial): Statistical analysis plan for an international, randomised, double blind, placebo-controlled trial. (2019)
Brenner, Amy Charlotte; Afolabi, Adefemi; Ahmad, Syed Masroor; Arribas, Monica; Chaudhri, Rizwana; Coats, Timothy; Cuzick, Jack; Gilmore, Ian; Hawkey, Christopher; Jairath, Vipul; Javaid, Kiran; Kayani, Aasia; Mutti, Muttiullah; Nadeem, Muhammad Arif; Shakur-Still, Haleema; Stanworth, Simon; Veitch, Andrew; Roberts, Ian
A randomized controlled trial of an intervention delivered by mobile phone text message to increase the acceptability of effective contraception among young women in Palestine. (2019)
McCarthy, Ona L; Zghayyer, Hanadi; Stavridis, Amina; Adada, Samia; Ahamed, Irrfan; Leurent, Baptiste; Edwards, Phil; Palmer, Melissa; Free, Caroline
February 2019
Effects of school environments on student risk-behaviours: evidence from a longitudinal study of secondary schools in England. (2019)
Bonell, Chris; Beaumont, Emma; Dodd, Matthew; Elbourne, Diana Ruth; Bevilacqua, Leonardo; Mathiot, Anne; McGowan, Jennifer; Sturgess, Joanna; Warren, Emily; Viner, Russell M; Allen, Elizabeth
No effect of tranexamic acid on platelet function and thrombin generation (ETAPlaT) in postpartum haemorrhage: a randomised placebo-controlled trial. (2019)
Dallaku, Kastriot; Shakur-Still, Haleema; Beaumont, Danielle; Roberts, Ian; Huque, Sumaya; Delius, Maria; Holdenrieder, Stefan; Gliozheni, Orion; Mansmann, Ulrich
No effect of tranexamic acid on platelet function and thrombin generation (ETAPlaT) in postpartum haemorrhage: a randomised placebo-controlled trial. (2019)
Dallaku, Kastriot; Shakur-Still, Haleema; Beaumont, Danielle; Roberts, Ian; Huque, Sumaya; Delius, Maria; Holdenrieder, Stefan; Gliozheni, Orion; Mansmann, Ulrich
Examining intervention mechanisms of action using mediation analysis within a randomised trial of a whole-school health intervention. (2019)
Bonell, Chris; Allen, Elizabeth; Opondo, Charles; Warren, Emily; Elbourne, Diana Ruth; Sturgess, Joanna; Bevilacqua, Leonardo; McGowan, Jennifer; Mathiot, Anne; Viner, Russell M
January 2019
MesoTRAP: a feasibility study that includes a pilot clinical trial comparing video-assisted thoracoscopic partial pleurectomy decortication with indwelling pleural catheter in patients with trapped lung due to malignant pleural mesothelioma designed to address recruitment and randomisation uncertainties and sample size requirements for a phase III trial. (2019)
Matthews, Claire; Freeman, Carol; Sharples, Linda D; Fox-Rushby, Julia; Tod, Angela; Maskell, Nicholas A; Edwards, John G; Coonar, Aman S; Sivasothy, Pasupathy; Hughes, Victoria; Rahman, Najib M; Waller, David A; Rintoul, Robert Campbell
Seasonal malaria chemoprevention packaged with malnutrition prevention in northern Nigeria: A pragmatic trial (SMAMP study) with nested case-control. (2019)
Ward, Abigail; Guillot, Andrea; Nepomnyashchiy, Lyudmila E; Graves, Justin C; Maloney, Kathleen; Omoniwa, Omowunmi F; Emegbuonye, Leslie; Opondo, Charles; Kerac, Marko; Omoluabi, Elizabeth; Bhattacharya, Antoinette; Milch Hariharan, Karen; Wiwa, Owens; Cohen, Justin M; Le Menach, Arnaud
Protocol for pilot cluster RCT of project respect: a school-based intervention to prevent dating and relationship violence and address health inequalities among young people. (2019)
Meiksin, Rebecca; Allen, Elizabeth; Crichton, Joanna; Morgan, Gemma S; Barter, Christine; Elbourne, Diana; Hunt, Kate; Melendez-Torres, GJ; Morris, Steve; Reyes, H Luz Mc Naughton; Sturgess, Joanna; Taylor, Bruce; Young, Honor; Campbell, Rona; Bonell, Chris
