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Number of items: 39.
Article
Abaasa, Andrew;
Asiki, Gershim;
Obuku Ekii, Andrew;
Wanyenze, Josephine;
Pala, Pietro;
J. van Dam, Govert;
L.A.M. Corstjens, Paul;
Hughes, Peter;
Ding, Song;
Pantaleo, Giuseppe;
+3 more...
Kaleebu, Pontiano;
M. Elliott, Alison;
Kamali, Anatoli;
(2018)
Effect of high-intensity versus low-intensity praziquantel treatment on HIV disease progression in HIV and Schistosoma mansoni co-infected patients: a randomised controlled trial.
Wellcome Open Research, 3.
p. 81.
DOI: https://doi.org/10.12688/wellcomeopenres.14683.1
Abaasa, Andrew;
Asiki, Gershim;
Obuku Ekii, Andrew;
Wanyenze, Josephine;
Pala, Pietro;
J. van Dam, Govert;
L.A.M. Corstjens, Paul;
Hughes, Peter;
Ding, Song;
Pantaleo, Giuseppe;
+3 more...
Kaleebu, Pontiano;
M. Elliott, Alison;
Kamali, Anatoli;
(2019)
Effect of high-intensity versus low-intensity praziquantel treatment on HIV disease progression in HIV and Schistosoma mansoni co-infected patients: a randomised controlled trial.
Wellcome Open Research, 3.
p. 81.
DOI: https://doi.org/10.12688/wellcomeopenres.14683.2
Barry, Aissata;
Behet, Marije;
Nébié, Issa;
Lanke, Kjerstin;
Grignard, Lynn;
Ouedraogo, Alphonse;
Soulama, Issiaka;
Drakeley, Chris;
Sauerwein, Robert;
Bolscher, Judith;
+4 more...
Dechering, Koen;
Bousema, Teun;
Tiono, Alfred;
Gonçalves, Bronner;
(2018)
Functional antibodies against Plasmodium falciparum sporozoites are associated with a longer time to qPCR-detected infection among schoolchildren in Burkina Faso.
Wellcome Open Research, 3.
p. 159.
DOI: https://doi.org/10.12688/wellcomeopenres.14932.1
Burns, Rachel;
Pathak, Neha;
Campos-Matos, Ines;
Zenner, Dominik;
Vittal Katikireddi, Srinivasa;
Muzyamba, Morris C;
Miranda, J Jaime;
Gilbert, Ruth;
Rutter, Harry;
Jones, Lucy;
+6 more...
Williamson, Elizabeth;
Hayward, Andrew C;
Smeeth, Liam;
Abubakar, Ibrahim;
Hemingway, Harry;
Aldridge, Robert W;
(2019)
Million Migrants study of healthcare and mortality outcomes in non-EU migrants and refugees to England: Analysis protocol for a linked population-based cohort study of 1.5 million migrants.
Wellcome Open Research, 4.
4-.
ISSN 2398-502X
DOI: https://doi.org/10.12688/wellcomeopenres.15007.1
Burns, Rachel;
Pathak, Neha;
Campos-Matos, Ines;
Zenner, Dominik;
Vittal Katikireddi, Srinivasa;
Muzyamba, Morris;
Miranda, Jaime;
Gilbert, Ruth;
Rutter, Harry;
Jones, Lucy;
+6 more...
Williamson, Elizabeth;
Hayward, Andrew;
Smeeth, Liam;
Abubakar, Ibrahim;
Hemingway, Harry;
Aldridge, Robert;
(2019)
Million Migrants study of healthcare and mortality outcomes in non-EU migrants and refugees to England: Analysis protocol for a linked population-based cohort study of 1.5 million migrants.
Wellcome Open Research, 4.
p. 4.
DOI: https://doi.org/10.12688/wellcomeopenres.15007.1
Butcher, Robert;
Sokana, Oliver;
Jack, Kelvin;
Sui, Leslie;
Russell, Charles;
Last, Anna;
Martin, Diana;
Burton, Matthew;
Solomon, Anthony;
Mabey, David CW;
+1 more...
Roberts, Chrissy;
(2018)
Clinical signs of trachoma are prevalent among Solomon Islanders who have no persistent markers of prior infection with Chlamydia trachomatis.
Wellcome Open Research, 3.
p. 14.
DOI: https://doi.org/10.12688/wellcomeopenres.13423.2
Butcher, Robert;
Sokana, Oliver;
Jack, Kelvin;
Sui, Leslie;
Russell, Charles;
Last, Anna;
Martin, Diana;
Burton, Matthew;
Solomon, Anthony;
Mabey, David CW;
+1 more...
Roberts, Chrissy;
(2018)
Clinical signs of trachoma are prevalent among Solomon Islanders who have no persistent markers of prior infection with Chlamydia trachomatis.
Wellcome Open Research, 3.
p. 14.
DOI: https://doi.org/10.12688/wellcomeopenres.13423.1
Cook, Sarah;
Malyutina, Sofia;
Kudryavtsev, Alexander;
Averina, Maria;
Bobrova, Natalia;
Boytsov, Sergey;
Brage, Soren;
Clark, Taane;
Diez Benavente, Ernest;
Eggen, Anne Elise;
+26 more...
Hopstock, Laila;
Hughes, Alun;
Johansen, Heidi;
Kholmatova, Kamila;
Kichigina, Anastasiya;
Kontsevaya, Anna;
Kornev, Michael;
Leong, Darryl;
Magnus, Per;
Mathiesen, Ellisiv;
McKee, Martin;
Morgan, Katy;
Nilssen, Odd;
Plakhov, Ilya;
Quint, Jennifer;
Rapala, Alicja;
Ryabikov, Andrey;
Saburova, Lyudmila;
Schirmer, Henrik;
Shapkina, Marina;
Shiekh, Suhail;
Shkolnikov, Vladimir;
Stylidis, Michael;
Voevoda, Michael;
Westgate, Kate;
Leon, David;
(2018)
Know Your Heart: Rationale, design and conduct of a cross-sectional study of cardiovascular structure, function and risk factors in 4500 men and women aged 35-69 years from two Russian cities, 2015-18.
Wellcome Open Research.
ISSN 2398-502X
DOI: https://doi.org/10.12688/wellcomeopenres.14619.3
Cook, Sarah;
Malyutina, Sofia;
Kudryavtsev, Alexander;
Averina, Maria;
Bobrova, Natalia;
Boytsov, Sergey;
Brage, Soren;
Clark, Taane;
Diez Benavente, Ernest;
Eggen, Anne Elise;
+26 more...
Hopstock, Laila;
Hughes, Alun;
Johansen, Heidi;
Kholmatova, Kamila;
Kichigina, Anastasiya;
Kontsevaya, Anna;
Kornev, Michael;
Leong, Darryl;
Magnus, Per;
Mathiesen, Ellisiv;
McKee, Martin;
Morgan, Katy;
Nilssen, Odd;
Plakhov, Ilya;
Quint, Jennifer;
Rapala, Alicja;
Ryabikov, Andrey;
Saburova, Lyudmila;
Schirmer, Henrik;
Shapkina, Marina;
Shiekh, Suhail;
Shkolnikov, Vladimir;
Stylidis, Michael;
Voevoda, Michael;
Westgate, Kate;
Leon, David;
(2018)
Know Your Heart: Rationale, design and conduct of a cross-sectional study of cardiovascular structure, function and risk factors in 4500 men and women aged 35-69 years from two Russian cities, 2015-18.
Wellcome Open Research, 3.
p. 67.
DOI: https://doi.org/10.12688/wellcomeopenres.14619.1
Cook, Sarah;
Malyutina, Sofia;
Kudryavtsev, Alexander;
Averina, Maria;
Bobrova, Natalia;
Boytsov, Sergey;
Brage, Soren;
Clark, Taane;
Diez Benavente, Ernest;
Eggen, Anne Elise;
+26 more...
Hopstock, Laila;
Hughes, Alun;
Johansen, Heidi;
Kholmatova, Kamila;
Kichigina, Anastasiya;
Kontsevaya, Anna;
Kornev, Michael;
Leong, Darryl;
Magnus, Per;
Mathiesen, Ellisiv;
McKee, Martin;
Morgan, Katy;
Nilssen, Odd;
Plakhov, Ilya;
Quint, Jennifer;
Rapala, Alicja;
Ryabikov, Andrey;
Saburova, Lyudmila;
Schirmer, Henrik;
Shapkina, Marina;
Shiekh, Suhail;
Shkolnikov, Vladimir;
Stylidis, Michael;
Voevoda, Michael;
Westgate, Kate;
Leon, David;
(2018)
Know Your Heart: Rationale, design and conduct of a cross-sectional study of cardiovascular structure, function and risk factors in 4500 men and women aged 35-69 years from two Russian cities, 2015-18.
Wellcome Open Research, 3.
p. 67.
DOI: https://doi.org/10.12688/wellcomeopenres.14619.3
Dallaku, Kastriot;
Shakur-Still, Haleema;
Beaumont, Danielle;
Roberts, Ian;
Huque, Sumaya;
Delius, Maria;
Holdenrieder, Stefan;
Gliozheni, Orion;
Mansmann, Ulrich;
(2019)
No effect of tranexamic acid on platelet function and thrombin generation (ETAPlaT) in postpartum haemorrhage: a randomised placebo-controlled trial.
Wellcome Open Research, 4.
p. 21.
DOI: https://doi.org/10.12688/wellcomeopenres.14977.1
Dance, David AB;
Knappik, Michael;
Dittrich, Sabine;
Davong, Viengmon;
Silisouk, Joy;
Vongsouvath, Manivanh;
Rattanavong, Sayaphet;
Pierret, Alain;
Newton, Paul N;
Amornchai, Premjit;
+3 more...
Wuthiekanun, Vanaporn;
Langla, Sayan;
Limmathurotsakul, Direk;
(2018)
Evaluation of consensus method for the culture of Burkholderia pseudomallei in soil samples from Laos.
Wellcome Open Research, 3.
132-.
ISSN 2398-502X
DOI: https://doi.org/10.12688/wellcomeopenres.14851.2
Gupta, Priti;
Prieto-Merino, David;
Ajay, Vamadevan;
Singh, Kalpana;
Roy, Ambuj;
Krishnan, Anand;
Narayan, KM Venkat;
Ali, Mohammed;
Tandon, Nikhil;
Prabhakaran, Dorairaj;
+1 more...
Perel, Pablo;
(2019)
Cardiovascular risk prediction in India: comparison of the original and recalibrated Framingham prognostic models in urban populations.
Wellcome Open Research, 4 (71).
DOI: https://doi.org/10.12688/wellcomeopenres.15137.1
Jeffries, Claire;
Lawrence, Gena;
Golovko, George;
Kristan, Mojca;
Orsborne, James;
Spence, Kirstin;
Hurn, Eliot;
Bandibabone, Janvier;
Tantely, Luciano;
Raharimalala, Fara;
+16 more...
Keita, Kalil;
Camara, Denka;
Barry, Yaya;
Wat’senga, Francis;
Manzambi, Emile;
Afrane, Yaw;
Mohammed, Abdul;
Abeku, Tarekegn;
Hedge, Shivanand;
Khanipov, Kamil;
Pimenova, Maria;
Fofanov, Yuriy;
Boyer, Sebastien;
Irish, Seth;
Hughes, Grant;
Walker, Thomas;
(2018)
Novel Wolbachia strains in Anopheles malaria vectors from Sub-Saharan Africa.
Wellcome Open Research, 3.
p. 113.
DOI: https://doi.org/10.12688/wellcomeopenres.14765.2
Kalyesubula, Robert;
Hau, Jeffrey;
Asiki, Gershim;
Ssebunya, Billy;
Kusemererwa, Sylvia;
Seeley, Janet;
Smeeth, Liam;
Tomlinson, Laurie;
Newton, Robert;
(2018)
Impaired renal function in a rural Ugandan population cohort.
Wellcome Open Research, 3.
p. 149.
DOI: https://doi.org/10.12688/wellcomeopenres.14863.1
Kalyesubula, Robert;
Hau, Jeffrey;
Asiki, Gershim;
Ssebunya, Billy;
Kusemererwa, Sylvia;
Seeley, Janet;
Smeeth, Liam;
Tomlinson, Laurie;
Newton, Robert;
(2019)
Impaired renal function in a rural Ugandan population cohort.
Wellcome Open Research, 3.
p. 149.
DOI: https://doi.org/10.12688/wellcomeopenres.14863.2
Kalyesubula, Robert;
Hau, Jeffrey;
Asiki, Gershim;
Ssebunya, Billy;
Kusemererwa, Sylvia;
Seeley, Janet;
Smeeth, Liam;
Tomlinson, Laurie;
Newton, Robert;
(2019)
Impaired renal function in a rural Ugandan population cohort.
Wellcome Open Research.
DOI: https://doi.org/10.12688/wellcomeopenres.14863.3
Kamau, Alice;
Mwangangi, Joseph;
Rono, Martin;
Mogeni, Polycarp;
Omedo, Irene;
Midega, Janet;
Scott, Anthony;
Bejon, Philip;
(2018)
Variation in the effectiveness of insecticide treated nets against malaria and outdoor biting by vectors in Kilifi, Kenya.
Wellcome Open Research, 2.
p. 22.
DOI: https://doi.org/10.12688/wellcomeopenres.11073.4
Ker, Katharine;
Prieto-Merino, David;
Sprigg, Nikola;
Mahmood, Abda;
Bath, Philip;
Kang Law, Zhe;
Flaherty, Katie;
Roberts, Ian;
(2019)
The effectiveness and safety of anti-fibrinolytics in patients with acute intracranial haemorrhage: statistical analysis plan for an individual patient data meta-analysis.
Wellcome Open Research, 2.
p. 120.
DOI: https://doi.org/10.12688/wellcomeopenres.13262.3
Kuper, Hannah;
Lyra, Tereza Maciel;
Moreira, Maria Elisabeth Lopes;
de Albuquerque, Maria do Socorro Veloso;
de Araújo, Thália Velho Barreto;
Fernandes, Silke;
Jofre-Bonet, Mireia;
Larson, Heidi;
Lopes de Melo, Ana Paula;
Mendes, Corina Helena Figueira;
+7 more...
Moreira, Martha Cristina Nunes;
do Nascimento, Marcos Antonio Ferreira;
Penn-Kekana, Loveday;
Pimentel, Camila;
Pinto, Marcia;
Simas, Clarissa;
Valongueiro, Sandra;
(2018)
Social and economic impacts of congenital Zika syndrome in Brazil: Study protocol and rationale for a mixed-methods study.
Wellcome Open Research, 3.
p. 127.
DOI: https://doi.org/10.12688/wellcomeopenres.14838.1
Lewin, Alex;
Hamilton, Shea;
Witkover, Aviva;
Langford, Paul;
Nicholas, Richard;
Chataway, Jeremy;
Bangham, Charles RM;
(2017)
Free serum haemoglobin is associated with brain atrophy in secondary progressive multiple sclerosis.
Wellcome Open Research, 1.
p. 10.
DOI: https://doi.org/10.12688/wellcomeopenres.9967.1
MacPherson, Peter;
Webb, Emily;
Lalloo, David;
Nliwasa, Marriott;
Maheswaran, Hendramoorthy;
Joekes, Elizabeth;
Phiri, Dama;
Squire, Bertie;
Pai, Madhukar;
Corbett, Elizabeth;
(2018)
Design and protocol for a pragmatic randomised study to optimise screening, prevention and care for tuberculosis and HIV in Malawi (PROSPECT Study).
Wellcome Open Research, 3.
p. 61.
DOI: https://doi.org/10.12688/wellcomeopenres.14598.2
MacPherson, Peter;
Webb, Emily;
Lalloo, David;
Nliwasa, Marriott;
Maheswaran, Hendramoorthy;
Joekes, Elizabeth;
Phiri, Dama;
Squire, Bertie;
Pai, Madhukar;
Corbett, Elizabeth;
(2018)
Design and protocol for a pragmatic randomised study to optimise screening, prevention and care for tuberculosis and HIV in Malawi (PROSPECT Study).
Wellcome Open Research, 3.
p. 61.
DOI: https://doi.org/10.12688/wellcomeopenres.14598.1
Mahmood, Abda;
Roberts, Ian;
Shakur-Still, Haleema;
(2019)
A nested randomised trial of the effect of tranexamic acid on intracranial haemorrhage and infarction in traumatic brain injury (CRASH-3 trial intracranial bleeding mechanistic study): Statistical analysis plan.
Wellcome Open Research, 3.
p. 99.
DOI: https://doi.org/10.12688/wellcomeopenres.14731.2
Maitland, Kathryn;
Kiguli, Sarah;
Opoka, Robert;
Olupot-Olupot, Peter;
Engoru, Charles;
Njuguna, Patricia;
Bandika, Victor;
Mpoya, Ayub;
Bush, Andrew;
Williams, Thomas;
+5 more...
Grieve, Richard;
Sadique, Zia;
Fraser, John;
Harrison, David;
Rowan, Kathy;
(2018)
Children’s Oxygen Administration Strategies Trial (COAST): A randomised controlled trial of high flow versus oxygen versus control in African children with severe pneumonia.
Wellcome Open Research, 2.
p. 100.
DOI: https://doi.org/10.12688/wellcomeopenres.12747.2
Mokaya, Jolynne;
McNaughton, Anna;
Burbridge, Lela;
Maponga, Tongai;
O'Hara, Geraldine;
Andersson, Monique;
Seeley, Janet;
Matthews, Philippa;
(2018)
A blind spot? Confronting the stigma of hepatitis B virus (HBV) infection - A systematic review.
Wellcome Open Research, 3.
p. 29.
DOI: https://doi.org/10.12688/wellcomeopenres.14273.1
Nakanga, Wisdom;
Prynn, Josephine;
Banda, Louis;
Kalyesubula, Robert;
Tomlinson, Laurie;
Nyirenda, Moffat;
Crampin, Amelia;
(2019)
Prevalence of impaired renal function among rural and urban populations: findings of a cross-sectional study in Malawi.
Wellcome Open Research, 4 (92).
DOI: https://doi.org/10.12688/wellcomeopenres.15255.1
Nampijja, Margaret;
Kizindo, Robert;
Apule, Barbara;
Lule, Swaib;
Muhangi, Lawrence;
Titman, Andrew;
Elliott, Alison;
Alcock, Katie;
Lewis, Charlie;
(2018)
The role of the home environment in neurocognitive development of children living in extreme poverty and with frequent illnesses: a cross-sectional study.
Wellcome Open Research, 3.
p. 152.
DOI: https://doi.org/10.12688/wellcomeopenres.14702.1
Nyundo, Christopher;
Doyle, Aoife;
Walumbe, David;
Otiende, Mark;
Kinuthia, Michael;
Amadi, David;
Jibendi, Boniface;
Mochamah, George;
Kihuha, Norbert;
Williams, Thomas;
+2 more...
Ross, David;
Bauni, Evasius;
(2017)
Linking health facility data from young adults aged 18-24 years to longitudinal demographic data: Experience from The Kilifi Health and Demographic Surveillance System.
Wellcome Open Research, 2.
p. 51.
DOI: https://doi.org/10.12688/wellcomeopenres.11302.1
Ramesh, Anita;
Jeffries, Claire;
Castanha, Priscila;
Oliveira, Paula;
Alexander, Neal;
Cameron, Mary;
Braga, Cynthia;
Walker, Thomas;
(2019)
No evidence of Zika, dengue, or chikungunya virus infection in field-caught mosquitoes from the Recife Metropolitan Region, Brazil, 2015.
Wellcome Open Research, 4.
p. 93.
DOI: https://doi.org/10.12688/wellcomeopenres.15295.1
Roberts, Ian;
Belli, Antonio;
Brenner, Amy;
Chaudhri, Rizwana;
Fawole, Bukola;
Harris, Tim;
Jooma, Rashid;
Mahmood, Abda;
Shokunbi, Temitayo;
Shakur, Haleema;
+1 more...
CRASH-3 trial collaborators;
(2018)
Tranexamic acid for significant traumatic brain injury (The CRASH-3 trial): Statistical analysis plan for an international, randomised, double-blind, placebo-controlled trial.
Wellcome Open Research, 3.
p. 86.
DOI: https://doi.org/10.12688/wellcomeopenres.14700.2
Roberts, Ian;
Belli, Antonio;
Brenner, Amy;
Chaudhri, Rizwana;
Fawole, Bukola;
Harris, Tim;
Jooma, Rashid;
Mahmood, Abda;
Shokunbi, Temitayo;
Shakur, Haleema;
+1 more...
CRASH-3 trial collaborators;
(2018)
Tranexamic acid for significant traumatic brain injury (The CRASH-3 trial): Statistical analysis plan for an international, randomised, double-blind, placebo-controlled trial.
Wellcome Open Research, 3.
p. 86.
DOI: https://doi.org/10.12688/wellcomeopenres.14700.2
Shakur-Still, Haleema;
Roberts, Ian;
Fawole, Bukola;
Kuti, Modupe;
Olayemi, Oladapo;
Bello, Adenike;
Huque, Sumaya;
Ogunbode, Olayinka;
Kotila, Taiwo;
Aimakhu, Chris;
+8 more...
Okunade, Olujide;
Olutogun, Tolulase;
Adetayo, Cecilia;
Dallaku, Kastriot;
Mansmann, Ulrich;
Hunt, Beverley;
Pepple, Tracey;
Balogun, Eni;
(2018)
Effect of tranexamic acid on coagulation and fibrinolysis in women with postpartum haemorrhage (WOMAN-ETAC): a single-centre, randomised, double-blind, placebo-controlled trial.
Wellcome Open Research, 3 (100).
ISSN 2398-502X
DOI: https://doi.org/10.12688/wellcomeopenres.14722.1
Toizumi, Michiko;
Yoshida, Lay-Myint;
Suzuki, Motoi;
Nguyen, Hien Anh Thi;
Pinsent, Amy;
Dang, Duc Anh;
Flasche, Stefan;
(2019)
Infant contact in day-care centres in Vietnam: A cross-sectional study to understand infant infection risk.
Wellcome Open Research, 4.
p. 75.
DOI: https://doi.org/10.12688/wellcomeopenres.15238.1
Toizumi, Michiko;
Yoshida, Lay-Myint;
Suzuki, Motoi;
Nguyen, Hien Anh Thi;
Pinsent, Amy;
Dang, Duc Anh;
Flasche, Stefan;
(2019)
Infant contact in day-care centres in Vietnam: A cross-sectional study to understand infant infection risk.
Wellcome Open Research, 4.
p. 75.
DOI: https://doi.org/10.12688/wellcomeopenres.15238.2
Tuomisto, Hanna;
Scheelbeek, Pauline FD;
Chalabi, Zaid;
Green, Rosemary;
Smith, Richard;
Haines, Andy;
Dangour, Alan;
(2017)
Effects of environmental change on agriculture, nutrition and health: A framework with a focus on fruits and vegetables.
Wellcome Open Research, 2.
p. 21.
DOI: https://doi.org/10.12688/wellcomeopenres.11190.2
Vallely, Andrew J;
Pomat, William S;
Homer, Caroline;
Guy, Rebecca;
Luchters, Stanley;
Mola, Glen DL;
Kariwiga, Grace;
Vallely, Lisa M;
Wiseman, Virginia;
Morgan, Chris;
+21 more...
Wand, Handan;
Rogerson, Stephen J;
Tabrizi, Sepehr N;
Whiley, David M;
Low, Nicola;
Peeling, Rosanna;
Siba, Peter;
Riddell, Michaela;
Laman, Moses;
Bolnga, John;
Robinson, Leanne J;
Morewaya, Jacob;
Badman, Steven G;
Batura, Neha;
Kelly-Hanku, Angela;
Toliman, Pamela J;
Peter, Wilfred;
Babona, Delly;
Peach, Elizabeth;
Garland, Suzanne M;
Kaldor, John M;
(2019)
Point-of-care testing and treatment of sexually transmitted infections to improve birth outcomes in high-burden, low-income settings: study protocol for a cluster randomized crossover trial (the WANTAIM Trial, Papua New Guinea).
Wellcome Open Research, 4 (53).
DOI: https://doi.org/10.12688/wellcomeopenres.15173.1
Vaughan, Megan;
Dube, Albert;
Namadingo, Hazel;
Crampin, Amelia;
Gondwe, Levie;
Kapira, Green;
Mbughi, Joyce;
Nyasulu, Maisha;
(2018)
Dietary change, noncommunicable disease and local knowledge: results of a small-scale study of the views of older Malawians.
Wellcome Open Research, 3.
p. 158.
DOI: https://doi.org/10.12688/wellcomeopenres.14887.1
Weobong, Benedict;
Weiss, Helen;
Cameron, Isobel;
Kung, Simon;
Patel, Vikram;
Hollon, Steven;
(2018)
Measuring depression severity in global mental health: comparing the PHQ-9 and the BDI-II.
Wellcome Open Research, 3.
p. 165.
DOI: https://doi.org/10.12688/wellcomeopenres.14978.1