Bate, A; Evans, SJ; (2009) Quantitative signal detection using spontaneous ADR reporting. Pharmacoepidemiology and drug safety, 18 (6). pp. 427-36. ISSN 1053-8569 DOI: https://doi.org/10.1002/pds.1742 Full text not available from this repository.

Beau, R; Douglas, I; Evans, S; Clayton, T; Smeeth, L; (2011) How Long Do Children Stay on Antiepileptic Treatments in the UK? [Conference or Workshop Item] https://researchonline.lshtm.ac.uk/id/eprint/2 Full text not available from this repository.

Beau, R; Douglas, I; Stephen, E; Clayton, T; Smeeth, L; (2011) Comparison of Retention Rates of First Line Antiepileptic Drugs in Children in the UK. [Conference or Workshop Item] https://researchonline.lshtm.ac.uk/id/eprint/1 Full text not available from this repository.

Bhaskaran, K; Douglas, I; Evans, S; van Staa, T; Smeeth, L; (2011) The Risk of Cancer Associated with Angiotensin-II Receptor Blockers. [Conference or Workshop Item] https://researchonline.lshtm.ac.uk/id/eprint/5 Full text not available from this repository.

Boggon, R; van Staa, TP; Chapman, M; Gallagher, AM; Hammad, TA; Richards, MA; (2013) Cancer recording and mortality in the General Practice Research Database and linked cancer registries. Pharmacoepidemiology and drug safety, 22 (2). pp. 168-175. ISSN 1053-8569 DOI: https://doi.org/10.1002/pds.3374 Full text not available from this repository.

Brauer, R; Douglas, I; Garcia Rodriguez, LA; Downey, G; Huerta, C; de Abajo, F; Bate, A; Feudjo Tepie, M; de Groot, MC; Schlienger, R; +4 more... Reynolds, R; Smeeth, L; Klungel, O; Ruigómez, A; (2015) Risk of acute liver injury associated with use of antibiotics. Comparative cohort and nested case-control studies using two primary care databases in Europe. Pharmacoepidemiology and drug safety, 25 Sup. pp. 29-38. ISSN 1053-8569 DOI: https://doi.org/10.1002/pds.3861 Full text not available from this repository.

Brauer, R; Douglas, I; Smeeth, L; (2011) Using the Self Controlled Case Series Method To Assess the Risk of Myocardial Infarction in GPRD-Registered Users of Antipsychotic Agents. [Conference or Workshop Item] https://researchonline.lshtm.ac.uk/id/eprint/6 Full text not available from this repository.

Brauer, R; Ruigómez, A; Downey, G; Bate, A; Garcia Rodriguez, LA; Huerta, C; Gil, M; de Abajo, F; Requena, G; Alvarez, Y; +13 more... Slattery, J; de Groot, M; Souverein, P; Hesse, U; Rottenkolber, M; Schmiedl, S; de Vries, F; Tepie, MF; Schlienger, R; Smeeth, L; Douglas, I; Reynolds, R; Klungel, O; (2015) Prevalence of antibiotic use: a comparison across various European health care data sources. Pharmacoepidemiology and drug safety, 25 Sup. pp. 11-20. ISSN 1053-8569 DOI: https://doi.org/10.1002/pds.3831 Full text not available from this repository.

Brauer, R; Smeeth, L; Anaya-Izquierdo, K; Farrington, CP; Whitaker, H; Douglas, I; (2012) A Comparison between the Standard Self Controlled Case Series Design and a Modification To Account for Events That Censor the Observation Period. [Conference or Workshop Item] https://researchonline.lshtm.ac.uk/id/eprint/612561 Full text not available from this repository.

Carpenter, J; Petersen, I; Welch, C; Bartlett, J; Walters, K; Morris, R; White, I; Marston, L; Nazareth, I; (2011) Multiple Imputation for Missing Data in Electronic Health Databases: Practical Issues and Some Solutions. [Conference or Workshop Item] https://researchonline.lshtm.ac.uk/id/eprint/4 Full text not available from this repository.

Cheng, J; Coope, C; Chai, J; Oliver, I; Kessel, A; Wang, D; Sun, Y; (2018) Knowledge and behaviors in relation to antibiotic use among rural residents in Anhui, China. Pharmacoepidemiology and drug safety. ISSN 1053-8569 DOI: https://doi.org/10.1002/pds.4429 Full text not available from this repository.

Chuang, CH; Doyle, P; Wang, JD; Chang, PJ; Lai, JN; Chen, PC; (2009) Herbal medicines during pregnancy and childhood cancers: an analysis of data from a pregnancy cohort study. Pharmacoepidemiology and drug safety, 18 (11). pp. 1119-1120. ISSN 1053-8569 DOI: https://doi.org/10.1002/pds.1835 Full text not available from this repository.

Cooper, AJP; Lettis, S; Chapman, CL; Evans, SJW; Waller, PC; Shakir, S; Payvandi, N; Murray, AB; (2008) Developing tools for the safety specification in risk management plans: lessons learned from a pilot project. Pharmacoepidemiology and drug safety, 17 (5). pp. 445-454. ISSN 1053-8569 DOI: https://doi.org/10.1002/pds.1576 Full text not available from this repository.

Crooks, C; Prieto-Merino, D; Evans, S; (2011) Identifying Adverse Events of Vaccines Using a Bayesian Method of Medically Guided Information Sharing. [Conference or Workshop Item] https://researchonline.lshtm.ac.uk/id/eprint/8 Full text not available from this repository.

Douglas, I; Smeeth, L; Hingorani, A; Grosso, A; Evans, S; (2011) A Cohort Study Using GPRD and MINAP Data To Investigate the Possible Drug Interaction between Clopidogrel and Cytochrome P450 2C19 Inhibitors. [Conference or Workshop Item] https://researchonline.lshtm.ac.uk/id/eprint/7 Full text not available from this repository.

Douglas, IJ; Smeeth, L; Evans, SJ; (2007) A propensity score controlled cohort study to investigate the effects of statins. [Conference or Workshop Item] https://researchonline.lshtm.ac.uk/id/eprint/8492 Full text not available from this repository.

Evans, SJ; Leufkens, HG; (2014) Regulatory decision-making: are we getting it right? Pharmacoepidemiology and drug safety, 23 (10). pp. 1012-6. ISSN 1053-8569 DOI: https://doi.org/10.1002/pds.3695 Full text not available from this repository.

Evans, SJW; Waller, PC; Davis, S; (2001) Use of proportional reporting ratios (PRRs) for signal generation from spontaneous adverse drug reaction reports. Pharmacoepidemiology and drug safety, 10 (6). pp. 483-486. ISSN 1053-8569 DOI: https://doi.org/10.1002/pds.677 Full text not available from this repository.

Gilmore, A; Milne, R; (2001) Methylphenidate in children with hyperactivity: review and cost-utility analysis. Pharmacoepidemiology and drug safety, 10 (2). pp. 85-94. ISSN 1053-8569 DOI: https://doi.org/10.1002/pds.564 Full text not available from this repository.

Hallgreen, CE; van Den Ham, HA; Mt-Isa, S; Ashworth, S; Hermann, R; Hobbiger, S; Luciani, D; Micaleff, A; Thomson, A; Wang, N; +14 more... van Staa, TP; Downey, G; Hirsch, I; Hockley, K; Juhaeri, J; Metcalf, M; Mwangi, J; Nixon, R; Peters, R; Stoeckert, I; Waddingham, E; Tzoulaki, I; Ashby, D; Wise, L; (2014) Benefit-risk assessment in a post-market setting: a case study integrating real-life experience into benefit-risk methodology. Pharmacoepidemiology and drug safety, 23 (9). pp. 974-983. ISSN 1053-8569 DOI: https://doi.org/10.1002/pds.3676 Full text not available from this repository.

Kremers, H M; Funch, D P; Robson, R A; Nalesnik, M A; Ebrahim, S; Cecka, M J; Opelz, G; Dreyer, N A; Walker, A M; (1999) A combination study design to examine mycophenolate mofetil (MMF) and PTLD in renal transplant patients. Pharmacoepidemiology and drug safety, 8 (7). pp. 509-18. ISSN 1053-8569 DOI: https://doi.org/10.1002/(SICI)1099-1557(199912)8:7<509::AID-PDS457>3.0.CO;2-1 Full text not available from this repository.

LI, YL; Weibel, D; Eskola, J; Larson, H; Zuber, P; Bonhoeffer, J; (2011) Post Marketing Vaccine Safety Monitoring in Low and Lower-Middle-Income Countries (LIC/LMIC). Pharmacoepidemiology and drug safety, 20. S357-S358. ISSN 1053-8569 https://researchonline.lshtm.ac.uk/id/eprint/18716 Full text not available from this repository.

Langham, J; Douglas, I; Brauer, R; Bhaskaran, K; Smeeth, L; (2011) A Self-Controlled Case-Series Study To Assess the Effect of Orlistat on the Risk of Idiopathic Acute Liver Injury, Using Data from the United Kingdom General Practice Research Database. Pharmacoepidemiology and drug safety, 20. S306-S306. ISSN 1053-8569 DOI: https://doi.org/10.1002/pds.2206 Full text not available from this repository.

Lo Re, V3rd; Haynes, K; Ming, EE; Wood Ives, J; Horne, LN; Fortier, K; Carbonari, DM; Hennessy, S; Cardillo, S; Reese, PP; +12 more... Reddy, KR; Margolis, D; Apter, A; Kimmel, SE; Roy, J; Freeman, CP; Razzaghi, H; Holick, CN; Esposito, DB; Van Staa, TP; Bhullar, H; Strom, BL; (2012) Safety of saxagliptin: rationale for and design of a series of postmarketing observational studies. Pharmacoepidemiology and drug safety, 21 (11). pp. 1202-15. ISSN 1053-8569 DOI: https://doi.org/10.1002/pds.3318 Full text not available from this repository.

Lodi, S; Evans, S; Carpenter, J; (2007) No evidence for anti-inflammatory effects of statins for rheumatoid arthritis patients in a large claims database. [Conference or Workshop Item] https://researchonline.lshtm.ac.uk/id/eprint/8471 Full text not available from this repository.

Maguire, A; Blak, BT; Thompson, M; (2009) The importance of defining periods of complete mortality reporting for research using automated data from primary care. Pharmacoepidemiology and drug safety, 18 (1). pp. 76-83. ISSN 1053-8569 DOI: https://doi.org/10.1002/pds.1688 Full text not available from this repository.

Maguire, A; Douglas, I; Smeeth, L; (2007) Patterns of cholesterol levels in patients treated with lipid lowering drugs in UK primary care. [Conference or Workshop Item] https://researchonline.lshtm.ac.uk/id/eprint/8494 Full text not available from this repository.

Maguire, A; Douglas, I; Smeeth, L; Thompson, M; (2007) Determinants of cholesterol and triglycerides recording in patients treated with lipid lowering therapy in UK primary care. [Conference or Workshop Item] https://doi.org/10.1002/pds Full text not available from this repository.

Maguire, A; Schwalm, MS; Douglas, I; Smeeth, L; (2007) Classification of hyperlipidemia from automated primary care data in the UK and France. [Conference or Workshop Item] https://researchonline.lshtm.ac.uk/id/eprint/8491 Full text not available from this repository.

Marston, L; Carpenter, JR; Walters, KR; Morris, RW; Nazareth, I; Petersen, I; (2010) Issues in multiple imputation of missing data for large general practice clinical databases. Pharmacoepidemiology and drug safety, 19 (6). pp. 618-626. ISSN 1053-8569 DOI: https://doi.org/10.1002/pds.1934 Full text not available from this repository.

McDowell, SE; Coleman, JJ; Evans, SJW; Gill, PS; Ferner, RE; (2010) Laboratory monitoring and adverse patient outcomes with antihypertensive therapy in primary care. Pharmacoepidemiology and drug safety, 19 (5). pp. 482-489. ISSN 1053-8569 DOI: https://doi.org/10.1002/pds.1935 Full text not available from this repository.

Petersen, I; Carpenter, J; Welch, C; Walters, K; Morris, R; White, I; Marston, L; Nazareth, I; (2011) Missing Data Imputation in Electronic Health Databases: Development of a Longitudinal Model for Cardiovascular Risk Factors. Pharmacoepidemiology and drug safety, 20. S231-S232. ISSN 1053-8569 https://researchonline.lshtm.ac.uk/id/eprint/18717 Full text not available from this repository.

Petersen, I; Gilbert, R; Evans, S; Nazareth, I; (2011) Pregnancy and Prescribed Psychotropic Medicine in Primary Care. Pharmacoepidemiology and drug safety, 20. S58-S58. ISSN 1053-8569 https://researchonline.lshtm.ac.uk/id/eprint/18719 Full text not available from this repository.

Rañopa, M; Douglas, I; van Staa, T; Smeeth, L; Klungel, O; Reynolds, R; Bhaskaran, K; (2014) The identification of incident cancers in UK primary care databases: a systematic review. Pharmacoepidemiology and drug safety, 24 (1). pp. 11-8. ISSN 1053-8569 DOI: https://doi.org/10.1002/pds.3729 Full text not available from this repository.

Rubino, A; Evans, SJ; Smeeth, L; (2006) Risk of stroke during treatment with atypical and conventional antipsychotics: A population-based study in the UK. [Conference or Workshop Item] https://researchonline.lshtm.ac.uk/id/eprint/10550 Full text not available from this repository.

Schoonen, WM; Evans, SJW; Hall, AJ; (2007) Smile plots to identify adverse drug reactions. [Conference or Workshop Item] https://researchonline.lshtm.ac.uk/id/eprint/8530 Full text not available from this repository.

Somers, EC; Thomas, SL; Smeeth, L; Hall, AJ; (2007) Co-existence of autoimmune diseases within individuals. [Conference or Workshop Item] https://researchonline.lshtm.ac.uk/id/eprint/8429 Full text not available from this repository.

Swenson, AJ; Mack, CD; Dreyer, NA; Adisasmito, W; Bamgboye, E; Chan, PKS; Coker, R; Dogan, N; Gasimov, V; Hanshaoworakul, W; +4 more... Lee, N; Oner, AF; Toovey, S; Zaman, M; (2011) Multiple Imputation: Application to a Global Avian Influenza Registry. Pharmacoepidemiology and drug safety, 20. S192-S192. ISSN 1053-8569 https://researchonline.lshtm.ac.uk/id/eprint/18722 Full text not available from this repository.

Tata, LJ; Lewis, SA; McKeever, TM; Smith, CJP; Doyle, P; Smeeth, L; Gibson, JE; Hubbard, RB; (2007) Congenital malformations in children born to women with asthma. [Conference or Workshop Item] https://researchonline.lshtm.ac.uk/id/eprint/8407 Full text not available from this repository.

Trifiro, G; Avillach, P; Gini, R; Coloma, P; Mazzaglia, G; Picelli, G; Scotti, L; Herings, R; Hippisley-Cox, J; Molokhia, M; +5 more... Pedersen, L; Reglat, AF; Pariente, A; Sturkenboom, M; van der Lei, J; (2011) Harmonization of the Event Identification Process in Eight European Healthcare Databases: The Experience from the EU-ADR Project. Pharmacoepidemiology and drug safety, 20. S4-S4. ISSN 1053-8569 https://researchonline.lshtm.ac.uk/id/eprint/18720 Full text not available from this repository.

Trifiro, G; Pariente, A; Coloma, PM; Kors, JA; Polimeni, G; Miremont-Salame, G; Catania, MA; Salvo, F; David, A; Moore, N; +8 more... Caputi, AP; Sturkenboom, M; Molokhia, M; Hippisley-Cox, J; Acedo, CD; van der Lei, J; Fourrier-Reglat, A; Grp, E.-, A; (2009) Data mining on electronic health record databases for signal detection in pharmacovigilance: which events to monitor? Pharmacoepidemiology and drug safety, 18 (12). pp. 1176-1184. ISSN 1053-8569 DOI: https://doi.org/10.1002/pds.1836 Full text not available from this repository.

Udo, R; Tcherny-Lessenot, S; Brauer, R; Dolin, P; Irvine, D; Wang, Y; Auclert, L; Juhaeri, J; Kurz, X; Abenhaim, L; +2 more... Grimaldi, L; De Bruin, ML; (2015) The risk of acute liver injury associated with the use of antibiotics-evaluating robustness of results in the pharmacoepidemiological research on outcomes of therapeutics by a European consortium (PROTECT) project. Pharmacoepidemiology and drug safety. ISSN 1053-8569 DOI: https://doi.org/10.1002/pds.3841 Full text not available from this repository.

Waller, P; Beard, K; Egberts, T; Evans, S; Hallas, J; Hasford, J; Laporte, JR; Moore, N; Shakir, S; Sturkenboom, M; (2008) European commission consultation on pharmacovigilance. Pharmacoepidemiology and drug safety, 17 (2). pp. 108-109. ISSN 1053-8569 DOI: https://doi.org/10.1002/pds.1526 Full text not available from this repository.

Waller, P; van Puijenbroek, E; Egberts, A; Evans, S; (2004) The reporting odds ratio versus the proportional reporting ratio: 'deuce'. Pharmacoepidemiology and drug safety, 13 (8). pp. 525-526. ISSN 1053-8569 DOI: https://doi.org/10.1002/pds.1002 Full text not available from this repository.

Waller, PC; Evans, SJW; (2003) A model for the future conduct of pharmacovigilance. Pharmacoepidemiology and drug safety, 12 (1). pp. 17-19. ISSN 1053-8569 DOI: https://doi.org/10.1002/pds.773 Full text not available from this repository.

Welch, C; Petersen, I; Walters, K; Morris, RW; Nazareth, I; Kalaitzaki, E; White, IR; Marston, L; Carpenter, J; (2012) Two-stage method to remove population- and individual-level outliers from longitudinal data in a primary care database. Pharmacoepidemiology and drug safety, 21 (7). pp. 725-732. ISSN 1053-8569 DOI: https://doi.org/10.1002/pds.2270 Full text not available from this repository.

van Staa, T P; Smeeth, L; Persson, I; Parkinson, J; Leufkens, H G M; (2008) Evaluating drug toxicity signals: is a hierarchical classification of evidence useful or a hindrance? Pharmacoepidemiology and drug safety, 17 (5). pp. 475-84. ISSN 1099-1557 https://researchonline.lshtm.ac.uk/id/eprint/20404 Full text not available from this repository.

van Staa, TP; Smeeth, L; Persson, I; Parkinson, J; Leufkens, HGM; (2008) Evaluating drug toxicity signals: is a hierarchical classification of evidence useful or a hindrance? Pharmacoepidemiology and drug safety, 17 (5). pp. 475-484. ISSN 1053-8569 DOI: https://doi.org/10.1002/pds.1568 Full text not available from this repository.

Brauer, R; Ruigómez, A; Klungel, O; Reynolds, R; Feudjo Tepie, M; Smeeth, L; Douglas, I; (2015) The risk of acute liver injury among users of antibiotic medications: a comparison of case-only studies. Pharmacoepidemiology and drug safety, 25 Sup. pp. 39-46. ISSN 1053-8569 DOI: https://doi.org/10.1002/pds.3846

Cid Ruzafa, J; Merinopoulou, E; Baggaley, RF; Leighton, P; Werther, W; Felici, D; Cox, A; (2016) Patient population with multiple myeloma and transitions across different lines of therapy in the USA: an epidemiologic model. Pharmacoepidemiology and drug safety, 25 (8). pp. 871-9. ISSN 1053-8569 DOI: https://doi.org/10.1002/pds.3927

Iwagami, M; Tomlinson, LA; Mansfield, KE; McDonald, HI; Smeeth, L; Nitsch, D; (2017) Prevalence, incidence, indication, and choice of antidepressants in patients with and without chronic kidney disease: a matched cohort study in UK Clinical Practice Research Datalink. Pharmacoepidemiology and drug safety. ISSN 1053-8569 DOI: https://doi.org/10.1002/pds.4212

Leite, A; Andrews, NJ; Thomas, SL; (2017) Assessing recording delays in general practice records to inform near real-time vaccine safety surveillance using the Clinical Practice Research Datalink (CPRD). Pharmacoepidemiology and drug safety. ISSN 1053-8569 DOI: https://doi.org/10.1002/pds.4173

Leite, A; Andrews, NJ; Thomas, SL; (2016) Near real-time vaccine safety surveillance using electronic health records-a systematic review of the application of statistical methods. Pharmacoepidemiology and drug safety, 25 (3). pp. 225-37. ISSN 1053-8569 DOI: https://doi.org/10.1002/pds.3966

Leite, A; Thomas, SL; Andrews, NJ; (2017) Do delays in data availability limit the implementation of near real-time vaccine safety surveillance using the Clinical Practice Research Datalink? Technical Report. Wiley. DOI: https://doi.org/10.1002/pds.4356

McGuinness, Luke A; Warren-Gash, Charlotte; Moorhouse, Louisa R; Thomas, Sara L; (2019) The validity of dementia diagnoses in routinely collected electronic health records in the United Kingdom: A systematic review. Pharmacoepidemiology and drug safety, 28 (2). pp. 244-255. ISSN 1053-8569 DOI: https://doi.org/10.1002/pds.4669

Requena, G; Logie, J; Martin, E; Boudiaf, N; González González, R; Huerta, C; Alvarez, A; Webb, D; Bate, A; García Rodríguez, LA; +7 more... Reynolds, R; Schlienger, R; Gardarsdottir, H; de Groot, M; Klungel, OH; de Abajo, F; Douglas, IJ; (2015) Do case-only designs yield consistent results across design and different databases? A case study of hip fractures and benzodiazepines. Pharmacoepidemiology and drug safety. ISSN 1053-8569 DOI: https://doi.org/10.1002/pds.3822

Sinnott, SJ; Normand, C; Byrne, S; Woods, N; Whelton, H; (2015) Copayments for prescription medicines on a public health insurance scheme in Ireland. Pharmacoepidemiology and drug safety. ISSN 1053-8569 DOI: https://doi.org/10.1002/pds.3917

Sinnott, Sarah-Jo; Smeeth, Liam; Williamson, Elizabeth; Perel, Pablo; Nitsch, Dorothea; Tomlinson, Laurie A; Douglas, Ian J; (2019) The comparative effectiveness of fourth-line drugs in resistant hypertension: An application in electronic health record data. Pharmacoepidemiology and drug safety. ISSN 1053-8569 DOI: https://doi.org/10.1002/pds.4808

Strongman, Helen; Williams, Rachael; Meeraus, Wilhelmine; Murray-Thomas, Tarita; Campbell, Jennifer; Carty, Lucy; Dedman, Daniel; Gallagher, Arlene; Oyinlola, Jessie; Kousoulis, Antonis; +1 more... Valentine, Janet; (2019) Limitations for health research with restricted data collection from UK primary care. Pharmacoepidemiology and drug safety. ISSN 1053-8569 DOI: https://doi.org/10.1002/pds.4765

Tham, MY; Ye, Q; Ang, PS; Fan, LY; Yoon, D; Park, RW; Ling, ZJ; Yip, JW; Tai, BC; Evans, SJ; +1 more... Sung, C; (2017) Application and optimisation of the Comparison on Extreme Laboratory Tests (CERT) algorithm for detection of adverse drug reactions: Transferability across national boundaries. Pharmacoepidemiology and drug safety, 27 (1). pp. 87-94. ISSN 1053-8569 DOI: https://doi.org/10.1002/pds.4340

Wang, SV; Schneeweiss, S; Berger, ML; Brown, J; de Vries, F; Douglas, I; Gagne, JJ; Gini, R; Klungel, O; Mullins, CD; +5 more... Nguyen, MD; Rassen, JA; Smeeth, L; Sturkenboom, M; joint ISPE-ISPOR Special Task Force on Real World Evidence in He; (2017) Reporting to Improve Reproducibility and Facilitate Validity Assessment for Healthcare Database Studies V1.0. Pharmacoepidemiology and drug safety, 26 (9). pp. 1018-1032. ISSN 1053-8569 DOI: https://doi.org/10.1002/pds.4295

de Groot, MC; Candore, G; Uddin, MJ; Souverein, PC; Ali, MS; Belitser, SV; Huerta, C; Groenwold, RH; Alvarez, Y; Slattery, J; +9 more... Korevaar, J; Hoes, AW; Roes, KC; de Boer, A; Douglas, IJ; Schlienger, RG; Reynolds, R; Klungel, OH; Gardarsdottir, H; (2016) Case-only designs for studying the association of antidepressants and hip or femur fracture. Pharmacoepidemiology and drug safety, 25 Sup. pp. 103-113. ISSN 1053-8569 DOI: https://doi.org/10.1002/pds.3850

de Jong, RG; Gallagher, AM; Herrett, E; Masclee, AA; Janssen-Heijnen, ML; de Vries, F; (2016) Comparability of the age and sex distribution of the UK Clinical Practice Research Datalink and the total Dutch population. Pharmacoepidemiology and drug safety, 25 (12). pp. 1460-1464. ISSN 1053-8569 DOI: https://doi.org/10.1002/pds.4074