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Number of items: 47.
Article
Baliani, A;
Bueno, GJ;
Stewart, ML;
Yardley, V;
Brun, R;
Barrett, MP;
Gilbert, IH;
(2005)
Design and Synthesis of a Series of Melamine-based Nitroheterocycles with Activity against Trypanosomatid Parasites.
Journal of medicinal chemistry, 48 (17).
pp. 5570-5579.
ISSN 0022-2623
DOI: https://doi.org/10.1021/jm050177+
Full text not available from this repository.
Baragaña, B;
Norcross, NR;
Wilson, C;
Porzelle, A;
Hallyburton, I;
Grimaldi, R;
Osuna-Cabello, M;
Norval, S;
Riley, J;
Stojanovski, L;
+17 more...
Simeons, FR;
Wyatt, PG;
Delves, MJ;
Meister, S;
Duffy, S;
Avery, VM;
Winzeler, EA;
Sinden, RE;
Wittlin, S;
Frearson, JA;
Gray, DW;
Fairlamb, AH;
Waterson, D;
Campbell, SF;
Willis, P;
Read, KD;
Gilbert, IH;
(2016)
Discovery of a Quinoline-4-carboxamide Derivative with a Novel Mechanism of Action, Multistage Antimalarial Activity, and Potent in Vivo Efficacy.
Journal of medicinal chemistry, 59 (21).
pp. 9672-9685.
ISSN 0022-2623
DOI: https://doi.org/10.1021/acs.jmedchem.6b00723
Brand, S;
Ko, EJ;
Viayna, E;
Thompson, S;
Spinks, D;
Thomas, M;
Sandberg, L;
Francisco, AF;
Jayawardhana, S;
Smith, VC;
+26 more...
Jansen, C;
De Rycker, M;
Thomas, J;
MacLean, L;
Osuna-Cabello, M;
Riley, J;
Scullion, P;
Stojanovski, L;
Simeons, FRC;
Epemolu, O;
Shishikura, Y;
Crouch, SD;
Bakshi, TS;
Nixon, CJ;
Reid, IH;
Hill, AP;
Underwood, TZ;
Hindley, SJ;
Robinson, SA;
Kelly, JM;
Fiandor, JM;
Wyatt, PG;
Marco, M;
Miles, TJ;
Read, KD;
Gilbert, IH;
(2017)
Discovery and Optimization of 5-Amino-1,2,3-triazole-4-carboxamide Series against Trypanosoma cruzi.
Journal of medicinal chemistry.
ISSN 0022-2623
DOI: https://doi.org/10.1021/acs.jmedchem.7b00463
Chauviere, G;
Bouteille, B;
Enanga, B;
de Albuquerque, C;
Croft, SL;
Dumas, M;
Perie, J;
(2003)
Synthesis and biological activity of nitro heterocycles analogous to megazol, a trypanocidal lead.
Journal of medicinal chemistry, 46 (3).
pp. 427-440.
ISSN 0022-2623
DOI: https://doi.org/10.1021/jm021030a
Full text not available from this repository.
Daunes, S;
D'Silva, C;
Kendrick, H;
Yardley, V;
Croft, SL;
(2001)
QSAR study on the contribution of log P and E-s to the in vitro antiprotozoal activity of glutathione derivatives.
Journal of medicinal chemistry, 44 (18).
pp. 2976-83.
ISSN 0022-2623
https://researchonline.lshtm.ac.uk/id/eprint/16567
Full text not available from this repository.
Ellis, GL;
Amewu, R;
Sabbani, S;
Stocks, PA;
Shone, A;
Stanford, D;
Gibbons, P;
Davies, J;
Vivas, L;
Charnaud, S;
+8 more...
Bongard, E;
Hall, C;
Rimmer, K;
Lozanom, S;
Jesus, M;
Gargallo, D;
Ward, SA;
O'Neill, PM;
(2008)
Two-step synthesis of achiral dispiro-1,2,4,5-tetraoxanes with outstanding antimalarial activity, low toxicity, and high-stability profiles.
Journal of medicinal chemistry, 51 (7).
pp. 2170-2177.
ISSN 0022-2623
https://researchonline.lshtm.ac.uk/id/eprint/7595
Full text not available from this repository.
Ellis, GL;
Amewu, R;
Sabbani, S;
Stocks, PA;
Shone, A;
Stanford, D;
Gibbons, P;
Davies, J;
Vivas, L;
Charnaud, S;
+8 more...
Bongard, E;
Hall, C;
Rimmer, K;
Lozanom, S;
Jesús, M;
Gargallo, D;
Ward, SA;
O'Neill, PM;
(2008)
Two-Step Synthesis of Achiral Dispiro-1,2,4,5-tetraoxanes with Outstanding Antimalarial Activity, Low Toxicity, and High-Stability Profiles.
Journal of medicinal chemistry, 51 (7).
pp. 2170-7.
ISSN 0022-2623
DOI: https://doi.org/10.1021/jm701435h
Full text not available from this repository.
Ersmark, K;
Feierberg, I;
Bjelic, S;
Hamelink, E;
Hackett, F;
Blackman, MJ;
Hultén, J;
Samuelsson, B;
Aqvist, J;
Hallberg, A;
(2004)
Potent inhibitors of the Plasmodium falciparum enzymes plasmepsin I and II devoid of cathepsin D inhibitory activity.
Journal of medicinal chemistry, 47 (1).
pp. 110-22.
ISSN 0022-2623
DOI: https://doi.org/10.1021/jm030933g
Full text not available from this repository.
Ersmark, K;
Nervall, M;
Hamelink, E;
Janka, LK;
Clemente, JC;
Dunn, BM;
Blackman, MJ;
Samuelsson, B;
Aqvist, J;
Hallberg, A;
(2005)
Synthesis of malarial plasmepsin inhibitors and prediction of binding modes by molecular dynamics simulations.
Journal of medicinal chemistry, 48 (19).
pp. 6090-106.
ISSN 0022-2623
DOI: https://doi.org/10.1021/jm050463l
Full text not available from this repository.
Fakih, S;
Podinovskaia, M;
Kong, X;
Collins, HL;
Schaible, UE;
Hider, RC;
(2008)
Targeting the lysosome: Fluorescent iron(III) chelators to selectively monitor endosomal/lysosomal labile iron pools.
Journal of medicinal chemistry, 51 (15).
pp. 4539-4552.
ISSN 0022-2623
DOI: https://doi.org/10.1021/jm8001247
Full text not available from this repository.
Fattorusso, C;
Campiani, G;
Kukreja, G;
Persico, M;
Butini, S;
Romano, MP;
Altarelli, M;
Rost, S;
Brindisi, M;
Savini, L;
+10 more...
Novellino, E;
Nacci, V;
Fattorusso, E;
Parapini, S;
Basilico, N;
Taramelli, D;
Yardley, V;
Croft, S;
Borriello, M;
Gemma, S;
(2008)
Design, synthesis, and structure-activity relationship studies of 4-quinolinyl- and 9-acrydinylhydrazones as potent antimalarial agents.
Journal of medicinal chemistry, 51 (5).
pp. 1333-1343.
ISSN 0022-2623
DOI: https://doi.org/10.1021/jm7012375
Full text not available from this repository.
Friebolin, W;
Jannack, B;
Wenzel, N;
Furrer, J;
Oeser, T;
Sanchez, CP;
Lanzer, M;
Yardley, V;
Becker, K;
Davioud-Charvet, E;
(2008)
Antimalarial dual drugs based on potent inhibitors of glutathione reductase from Plasmodium falciparum.
Journal of medicinal chemistry, 51 (5).
pp. 1260-1277.
ISSN 0022-2623
DOI: https://doi.org/10.1021/jm7009292
Full text not available from this repository.
Fytas, C;
Zoidis, G;
Tzoutzas, N;
Taylor, MC;
Fytas, G;
Kelly, JM;
(2011)
Novel Lipophilic Acetohydroxamic Acid Derivatives Based on Conformationally Constrained Spiro Carbocyclic 2,6-Diketopiperazine Scaffolds with Potent Trypanocidal Activity.
Journal of medicinal chemistry, 54 (14).
pp. 5250-5254.
ISSN 0022-2623
DOI: https://doi.org/10.1021/jm200217m
Gemma, S;
Campiani, G;
Butini, S;
Joshi, BP;
Kukreja, G;
Coccone, SS;
Bernetti, M;
Persico, M;
Nacci, V;
Fiorini, I;
+14 more...
Novellino, E;
Taramelli, D;
Basilico, N;
Parapini, S;
Yardley, V;
Croft, S;
Keller-Maerki, S;
Rottmann, M;
Brun, R;
Coletta, M;
Marini, S;
Guiso, G;
Caccia, S;
Fattorusso, C;
(2009)
Combining 4-Aminoquinoline- and Clotrimazole-Based Pharmacophores toward Innovative and Potent Hybrid Antimalarials.
Journal of medicinal chemistry, 52 (2).
pp. 502-513.
ISSN 0022-2623
DOI: https://doi.org/10.1021/jm801352s
Full text not available from this repository.
Gemma, S;
Campiani, G;
Butini, S;
Kukreja, G;
Coccone, SS;
Joshi, BP;
Persico, M;
Nacci, V;
Fiorini, I;
Novellino, E;
+12 more...
Fattorusso, E;
Taglialatela-Scafati, O;
Savini, L;
Taramelli, D;
Basilico, N;
Parapini, S;
Morace, G;
Yardley, V;
Croft, S;
Coletta, M;
Marini, S;
Fattorusso, C;
(2008)
Clotrimazole scaffold as an innovative pharmacophore towards potent antimalarial agents: Design, synthesis, and biological and structure-activity relationship studies.
Journal of medicinal chemistry, 51 (5).
pp. 1278-1294.
ISSN 0022-2623
DOI: https://doi.org/10.1021/jm701247k
Full text not available from this repository.
Gemma, S;
Campiani, G;
Butini, S;
Kukreja, G;
Joshi, BP;
Persico, M;
Catalanotti, B;
Novellino, E;
Fattorusso, E;
Nacci, V;
+6 more...
Savini, L;
Taramelli, D;
Basilico, N;
Morace, G;
Yardley, V;
Fattorusso, C;
(2007)
Design and Synthesis of Potent Antimalarial Agents Based on Clotrimazole Scaffold: Exploring an Innovative Pharmacophore.
Journal of medicinal chemistry, 50 (4).
pp. 595-8.
ISSN 0022-2623
DOI: https://doi.org/10.1021/jm061429p
Full text not available from this repository.
Ghosh, S;
Chan, JMW;
Lea, CR;
Meints, GA;
Lewis, JC;
Tovian, ZS;
Flessner, RM;
Loftus, TC;
Bruchhaus, I;
Kendrick, H;
+5 more...
Croft, SL;
Kemp, RG;
Kobayashi, S;
Nozaki, T;
Oldfield, E;
(2004)
Effects of bisphosphonates on the growth of Entamoeba histolytica and Plasmodium species in vitro and in vivo.
Journal of medicinal chemistry, 47 (1).
pp. 175-187.
ISSN 0022-2623
DOI: https://doi.org/10.1021/jm030084x
Full text not available from this repository.
Gros, L;
Lorente, SO;
Jimenez, CJ;
Yardley, V;
Rattray, L;
Wharton, H;
Little, S;
Croft, SL;
Ruiz-Perez, LM;
Gonzalez-Pacanowska, D;
+1 more...
Gilbert, IH;
(2006)
Evaluation of Azasterols as Anti-Parasitics.
Journal of medicinal chemistry, 49 (20).
pp. 6094-6103.
ISSN 0022-2623
DOI: https://doi.org/10.1021/jm060290f
Full text not available from this repository.
Hudock, MP;
Sanz-Rodriguez, CE;
Song, YC;
Chan, JMW;
Zhang, YH;
Odeh, S;
Kosztowski, T;
Leon-Rossell, A;
Concepcion, JL;
Yardley, V;
+3 more...
Croft, SL;
Urbina, JA;
Oldfield, E;
(2006)
Inhibition of Trypanosoma cruzi hexokinase by bisphosphonates.
Journal of medicinal chemistry, 49 (1).
pp. 215-223.
ISSN 0022-2623
DOI: https://doi.org/10.1021/jm0582625
Full text not available from this repository.
Johansson, PO;
Chen, Y;
Belfrage, AK;
Blackman, MJ;
Kvarnström, I;
Jansson, K;
Vrang, L;
Hamelink, E;
Hallberg, A;
Rosenquist, A;
+1 more...
Samuelsson, B;
(2004)
Design and synthesis of potent inhibitors of the malaria aspartyl proteases plasmepsin I and II. Use of solid-phase synthesis to explore novel statine motifs.
Journal of medicinal chemistry, 47 (13).
pp. 3353-66.
ISSN 0022-2623
DOI: https://doi.org/10.1021/jm031106i
Full text not available from this repository.
Johansson, PO;
Lindberg, J;
Blackman, MJ;
Kvarnström, I;
Vrang, L;
Hamelink, E;
Hallberg, A;
Rosenquist, A;
Samuelsson, B;
(2005)
Design and synthesis of potent inhibitors of plasmepsin I and II: X-ray crystal structure of inhibitor in complex with plasmepsin II.
Journal of medicinal chemistry, 48 (13).
pp. 4400-9.
ISSN 0022-2623
DOI: https://doi.org/10.1021/jm040884n
Full text not available from this repository.
Jung, MK;
Lee, K;
Kendrick, H;
Robinson, BL;
Croft, SL;
(2002)
Synthesis, stability, and antimalarial activity of new hydrolytically stable and water-soluble (+)-deoxoartelinic acid.
Journal of medicinal chemistry, 45 (22).
pp. 4940-4.
ISSN 0022-2623
DOI: https://doi.org/10.1021/jm020244p
Full text not available from this repository.
Lee, B;
Bauer, H;
Melchers, J;
Ruppert, T;
Rattray, L;
Yardley, V;
Davioud-Charvet, E;
Krauth-Siegel, RL;
(2005)
Irreversible Inactivation of Trypanothione Reductase by Unsaturated Mannich Bases: A Divinyl Ketone as Key Intermediate.
Journal of medicinal chemistry, 48 (23).
pp. 7400-7410.
ISSN 0022-2623
DOI: https://doi.org/10.1021/jm0504860
Full text not available from this repository.
Leven, M;
Knaab, TC;
Held, J;
Duffy, S;
Meister, S;
Fischli, C;
Meitzner, D;
Lehmann, U;
Lungerich, B;
Kuna, K;
+8 more...
Stahlke, P;
Delves, MJ;
Buchholz, M;
Winzeler, EA;
Avery, VM;
Mordmüller, B;
Wittlin, S;
Kurz, T;
(2017)
3-Hydroxy-N'-arylidenepropanehydrazonamides with Halo-Substituted Phenanthrene Scaffolds Cure P. berghei Infected Mice When Administered Perorally.
Journal of medicinal chemistry, 60 (14).
pp. 6036-6044.
ISSN 0022-2623
DOI: https://doi.org/10.1021/acs.jmedchem.7b00140
Full text not available from this repository.
Magaraci, F;
Jimenez, CJ;
Rodrigues, C;
Rodrigues, JCF;
Braga, MV;
Yardley, V;
de Luca-Fradley, K;
Croft, SL;
de Souza, W;
Ruiz-Perez, LM;
+3 more...
Urbina, J;
Pacanowska, DG;
Gilbert, IH;
(2003)
Azasterols as inhibitors of sterol 24-methyltransferase in leishmania species and Trypanosoma cruzi.
Journal of medicinal chemistry, 46 (22).
pp. 4714-4727.
ISSN 0022-2623
DOI: https://doi.org/10.1021/jm021114j
Full text not available from this repository.
Maldonado, CR;
Marín, C;
Olmo, F;
Huertas, O;
Quirós, M;
Sánchez-Moreno, M;
Rosales, MJ;
Salas, JM;
(2010)
In vitro and in vivo trypanocidal evaluation of nickel complexes with an azapurine derivative against Trypanosoma cruzi.
Journal of medicinal chemistry, 53 (19).
pp. 6964-72.
ISSN 0022-2623
DOI: https://doi.org/10.1021/jm100581z
Full text not available from this repository.
Mantyla, A;
Garnier, T;
Rautio, R;
Nevalainen, T;
Vepsalainen, J;
Koskinen, A;
Croft, SL;
Jarvinen, T;
(2004)
Synthesis, in vitro evaluation, and antileishmanial activity of water-soluble prodrugs of buparvaquone.
Journal of medicinal chemistry, 47 (1).
pp. 188-195.
ISSN 0022-2623
DOI: https://doi.org/10.1021/jm030868a
Full text not available from this repository.
Martin, MB;
Grimley, JS;
Lewis, JC;
Heath, HT;
Bailey, BN;
Kendrick, H;
Yardley, V;
Caldera, A;
Lira, R;
Urbina, JA;
+4 more...
Moreno, SNJ;
Docampo, R;
Croft, SL;
Oldfield, E;
(2001)
Bisphosphonates inhibit the growth of Trypanosoma brucei, Trypanosoma cruzi, Leishmania donovani, Toxoplasma gondii, and Plasmodium falciparum: A potential route to chemotherapy.
Journal of medicinal chemistry, 44 (6).
pp. 909-16.
ISSN 0022-2623
https://researchonline.lshtm.ac.uk/id/eprint/16563
Full text not available from this repository.
Martin, MB;
Sanders, JM;
Kendrick, H;
de Luca-Fradley, K;
Lewis, JC;
Grimley, JS;
van Brussel, EM;
Olsen, JR;
Meints, GA;
Burzynska, A;
+3 more...
Kafarski, P;
Croft, SL;
Oldfield, E;
(2002)
Activity of bisphosphonates against Trypanosoma brucei rhodesiense.
Journal of medicinal chemistry, 45 (14).
pp. 2904-14.
ISSN 0022-2623
DOI: https://doi.org/10.1021/jm0102809
Full text not available from this repository.
Neves, BJ;
Dantas, RF;
Senger, MR;
Melo-Filho, CC;
Valente, WC;
de Almeida, AC;
Rezende-Neto, JM;
Lima, EF;
Paveley, R;
Furnham, N;
+6 more...
Muratov, E;
Kamentsky, L;
Carpenter, AE;
Braga, RC;
Silva-Junior, FP;
Andrade, CH;
(2016)
Discovery of New Anti-Schistosomal Hits by Integration of QSAR-Based Virtual Screening and High Content Screening.
Journal of medicinal chemistry, 59 (15).
pp. 7075-88.
ISSN 0022-2623
DOI: https://doi.org/10.1021/acs.jmedchem.5b02038
O'Neill, PM;
Shone, AE;
Stanford, D;
Nixon, G;
Asadollahy, E;
Park, BK;
Maggs, JL;
Roberts, P;
Stocks, PA;
Biagini, G;
+19 more...
Bray, PG;
Davies, J;
Berry, N;
Hall, C;
Rimmer, K;
Winstanley, PA;
Hindley, S;
Bambal, RB;
Davis, CB;
Bates, M;
Gresham, SL;
Brigandi, RA;
Gomez-de-Las-Heras, FM;
Gargallo, DV;
Parapini, S;
Vivas, L;
Lander, H;
Taramelli, D;
Ward, SA;
(2009)
Synthesis, Antimalarial Activity, and Preclinical Pharmacology of a Novel Series of 4'-Fluoro and 4'-Chloro Analogues of Amodiaquine. Identification of a Suitable "Back-Up" Compound for N-tert-Butyl Isoquine.
Journal of medicinal chemistry, 52 (7).
pp. 1828-44.
ISSN 0022-2623
DOI: https://doi.org/10.1021/jm8012757
Full text not available from this repository.
Ohkanda, J;
Buckner, FS;
Lockman, JW;
Yokoyama, K;
Carrico, D;
Eastman, R;
de Luca-Fradley, K;
Davies, W;
Croft, SL;
van Voorhis, WC;
+3 more...
Gelb, MH;
Sebti, SM;
Hamilton, AD;
(2004)
Design and Synthesis of Peptidomimetic Protein Farnesyltransferase Inhibitors as Anti-Trypanosoma brucei Agents.
Journal of medicinal chemistry.
pp. 432-445.
ISSN 0022-2623
DOI: https://doi.org/10.1021/jm030236o
Full text not available from this repository.
Olmo, F;
Rotger, C;
Ramírez-Macías, I;
Martínez, L;
Marín, C;
Carreras, L;
Urbanová, K;
Vega, M;
Chaves-Lemaur, G;
Sampedro, A;
+3 more...
Rosales, MJ;
Sánchez-Moreno, M;
Costa, A;
(2014)
Synthesis and biological evaluation of N,N'-squaramides with high in vivo efficacy and low toxicity: toward a low-cost drug against Chagas disease.
Journal of medicinal chemistry, 57 (3).
pp. 987-99.
ISSN 0022-2623
DOI: https://doi.org/10.1021/jm4017015
Full text not available from this repository.
Onyeibor, O;
Croft, SL;
Dodson, HI;
Feiz-Haddad, M;
Kendrick, H;
Millington, NJ;
Parapini, S;
Phillips, RM;
Seville, S;
Shnyder, SD;
+2 more...
Taramelli, D;
Wright, CW;
(2005)
Synthesis of some cryptolepine analogues, assessment of their antimalarial and cytotoxic activities, and consideration of their antimalarial mode of action.
Journal of medicinal chemistry, 48 (7).
pp. 2701-9.
ISSN 0022-2623
DOI: https://doi.org/10.1021/jm040893w
Full text not available from this repository.
Pacorel, B;
Leung, SC;
Stachulski, AV;
Davies, J;
Vivas, L;
Lander, H;
Ward, SA;
Kaiser, M;
Brun, R;
O'Neill, PM;
(2010)
Modular Synthesis and in Vitro and in Vivo Antimalarial Assessment of C-10 Pyrrole Mannich Base Derivatives of Artemisinin.
Journal of medicinal chemistry, 53 (2).
pp. 633-640.
ISSN 0022-2623
DOI: https://doi.org/10.1021/jm901216v
Full text not available from this repository.
Papanastasiou, I;
Tsotinis, A;
Kolocouris, N;
Prathalingam, SR;
Kelly, JM;
(2008)
Design, synthesis, and trypanocidal activity of new aminoadamantane derivatives.
Journal of medicinal chemistry, 51 (5).
pp. 1496-1500.
ISSN 0022-2623
DOI: https://doi.org/10.1021/jm7014292
Full text not available from this repository.
Parveen, S;
Khan, MO;
Austin, SE;
Croft, SL;
Yardley, V;
Rock, P;
Douglas, KT;
(2005)
Antitrypanosomal, antileishmanial, and antimalarial activities of quaternary arylalkylammonium 2-amino-4-chlorophenyl phenyl sulfides, a new class of trypanothione reductase inhibitor, and of N-acyl derivatives of 2-amino-4-chlorophenyl phenyl sulfide.
Journal of medicinal chemistry, 48 (25).
pp. 8087-97.
ISSN 0022-2623
DOI: https://doi.org/10.1021/jm050819t
Full text not available from this repository.
Salmon-Chemin, L;
Buisine, E;
Yardley, V;
Kohler, S;
Debreu, MA;
Landry, V;
Sergheraert, C;
Croft, SL;
Krauth-Siegel, RL;
Davioud-Charvet, E;
(2001)
2-and 3-substituted 1,4-naphthoquinone derivatives as subversive substrates of trypanothione reductase and lipoamide dehydrogenase from Trypanosoma cruzi: Synthesis and correlation between redox cycling activities and in vitro cytotoxicity.
Journal of medicinal chemistry, 44 (4).
pp. 548-65.
ISSN 0022-2623
https://researchonline.lshtm.ac.uk/id/eprint/16559
Full text not available from this repository.
Stachulski, AV;
Berry, NG;
Lilian Low, AC;
Moores, SL;
Row, E;
Warhurst, DC;
Adagu, IS;
Rossignol, JF;
(2006)
Identification of Isoflavone Derivatives as Effective Anticryptosporidial Agents in Vitro and in Vivo.
Journal of medicinal chemistry, 49 (4).
pp. 1450-4.
ISSN 0022-2623
DOI: https://doi.org/10.1021/jm050973f
Full text not available from this repository.
Sánchez-Moreno, M;
Gómez-Contreras, F;
Navarro, P;
Marín, C;
Olmo, F;
Yunta, MJ;
Sanz, AM;
Rosales, MJ;
Cano, C;
Campayo, L;
(2012)
Phthalazine derivatives containing imidazole rings behave as Fe-SOD inhibitors and show remarkable anti-T. cruzi activity in immunodeficient-mouse mode of infection.
Journal of medicinal chemistry, 55 (22).
pp. 9900-13.
ISSN 0022-2623
DOI: https://doi.org/10.1021/jm3011004
Full text not available from this repository.
Sánchez-Moreno, M;
Marín, C;
Navarro, P;
Lamarque, L;
García-España, E;
Miranda, C;
Huertas, O;
Olmo, F;
Gómez-Contreras, F;
Pitarch, J;
+1 more...
Arrebola, F;
(2012)
In vitro and in vivo trypanosomicidal activity of pyrazole-containing macrocyclic and macrobicyclic polyamines: their action on acute and chronic phases of Chagas disease.
Journal of medicinal chemistry, 55 (9).
pp. 4231-43.
ISSN 0022-2623
DOI: https://doi.org/10.1021/jm2017144
Full text not available from this repository.
Sánchez-Moreno, M;
Sanz, AM;
Gómez-Contreras, F;
Navarro, P;
Marín, C;
Ramírez-Macias, I;
Rosales, MJ;
Olmo, F;
Garcia-Aranda, I;
Campayo, L;
+3 more...
Cano, C;
Arrebola, F;
Yunta, MJ;
(2011)
In vivo trypanosomicidal activity of imidazole- or pyrazole-based benzo[g]phthalazine derivatives against acute and chronic phases of Chagas disease.
Journal of medicinal chemistry, 54 (4).
pp. 970-9.
ISSN 0022-2623
DOI: https://doi.org/10.1021/jm101198k
Full text not available from this repository.
Thompson, AM;
O'Connor, PD;
Blaser, A;
Yardley, V;
Maes, L;
Gupta, S;
Launay, D;
Martin, D;
Franzblau, SG;
Wan, B;
+3 more...
Wang, Y;
Ma, Z;
Denny, WA;
(2016)
Repositioning Antitubercular 6-Nitro-2,3-dihydroimidazo[2,1-b][1,3]oxazoles for Neglected Tropical Diseases: Structure-Activity Studies on a Preclinical Candidate for Visceral Leishmaniasis.
Journal of medicinal chemistry.
ISSN 0022-2623
DOI: https://doi.org/10.1021/acs.jmedchem.5b01699
Thompson, AM;
O'Connor, PD;
Marshall, AJ;
Blaser, A;
Yardley, V;
Maes, L;
Gupta, S;
Launay, D;
Braillard, S;
Chatelain, E;
+5 more...
Wan, B;
Franzblau, SG;
Ma, Z;
Cooper, CB;
Denny, WA;
(2018)
Development of (6 R)-2-Nitro-6-[4-(trifluoromethoxy)phenoxy]-6,7-dihydro-5 H-imidazo[2,1- b][1,3]oxazine (DNDI-8219): A New Lead for Visceral Leishmaniasis.
Journal of medicinal chemistry.
ISSN 0022-2623
DOI: https://doi.org/10.1021/acs.jmedchem.7b01581
Thompson, AM;
O'Connor, PD;
Marshall, AJ;
Yardley, V;
Maes, L;
Gupta, S;
Launay, D;
Braillard, S;
Chatelain, E;
Franzblau, SG;
+5 more...
Wan, B;
Wang, Y;
Ma, Z;
Cooper, CB;
Denny, WA;
(2017)
7-Substituted 2-Nitro-5,6-dihydroimidazo[2,1-b][1,3]oxazines: Novel Antitubercular Agents Lead to a New Preclinical Candidate for Visceral Leishmaniasis.
Journal of medicinal chemistry, 60 (10).
pp. 4212-4233.
ISSN 0022-2623
DOI: https://doi.org/10.1021/acs.jmedchem.7b00034
Wright, CW;
Addae-Kyereme, J;
Breen, AG;
Brown, JE;
Cox, MF;
Croft, SL;
Gokcek, Y;
Kendrick, H;
Phillips, RM;
Pollet, PL;
(2001)
Synthesis and evaluation of cryptolepine analogues for their potential as new antimalarial agents.
Journal of medicinal chemistry, 44 (19).
pp. 3187-94.
ISSN 0022-2623
https://researchonline.lshtm.ac.uk/id/eprint/16568
Full text not available from this repository.
Yang, M;
Arai, C;
Md, AB;
Lu, J;
Ge, JF;
Pudhom, K;
Takasu, K;
Kasai, K;
Kaiser, M;
Brun, R;
+3 more...
Yardley, V;
Itoh, I;
Ihara, M;
(2010)
Fluorinated Rhodacyanine (SJL-01) Possessing High Efficacy for Visceral Leishmaniasis (VL).
Journal of medicinal chemistry, 53 (1).
pp. 368-373.
ISSN 0022-2623
DOI: https://doi.org/10.1021/jm9013086
Full text not available from this repository.