LSHTM Organisational Structure (62309)

Faculty of Infectious and Tropical Diseases (19963)

Department of Infection Biology (5999)

Dept of Immunology and Infection (-2019) (955) Month Authors/Creators Item Type Full Text

February 2018

Unravelling the immune signature of Plasmodium falciparum transmission-reducing immunity. (2017) Stone, Will JR; Campo, Joseph J; Ouédraogo, André Lin; Meerstein-Kessel, Lisette; Morlais, Isabelle; Da, Dari; Cohuet, Anna; Nsango, Sandrine; Sutherland, Colin J; van de Vegte-Bolmer, Marga; Siebelink-Stoter, Rianne; van Gemert, Geert-Jan; Graumans, Wouter; Lanke, Kjerstin; Shandling, Adam D; Pablo, Jozelyn V; Teng, Andy A; Jones, Sophie; de Jong, Roos M; Fabra-García, Amanda; Bradley, John; Roeffen, Will; Lasonder, Edwin; Gremo, Giuliana; Schwarzer, Evelin; Janse, Chris J; Singh, Susheel K; Theisen, Michael; Felgner, Phil; Marti, Matthias; Drakeley, Chris; Sauerwein, Robert; Bousema, Teun; Jore, Matthijs M

Efficacy and safety of primaquine and methylene blue for prevention of Plasmodium falciparum transmission in Mali: a phase 2, single-blind, randomised controlled trial. (2017) Dicko, Alassane; Roh, Michelle E; Diawara, Halimatou; Mahamar, Almahamoudou; Soumare, Harouna M; Lanke, Kjerstin; Bradley, John; Sanogo, Koualy; Kone, Daouda T; Diarra, Kalifa; Keita, Sekouba; Issiaka, Djibrilla; Traore, Sekou F; McCulloch, Charles; Stone, Will JR; Hwang, Jimee; Müller, Olaf; Brown, Joelle M; Srinivasan, Vinay; Drakeley, Chris; Gosling, Roly; Chen, Ingrid; Bousema, Teun

January 2018

Variation in natural exposure to anopheles mosquitoes and its effects on malaria transmission. (2017) Guelbéogo, Wamdaogo M; Gonçalves, Bronner Pamplona; Grignard, Lynn; Bradley, John; Serme, Samuel S; Hellewell, Joel; Lanke, Kjerstin; Zongo, Soumanaba; Sepúlveda, Nuno; Soulama, Issiaka; Wangrawa, Dimitri W; Yakob, Laith; Sagnon, N'Falé; Bousema, Teun; Drakeley, Chris

Hepcidin deficiency and iron deficiency do not alter tuberculosis susceptibility in a murine M.tb infection model. (2017) Harrington-Kandt, Rachel; Stylianou, Elena; Eddowes, Lucy A; Lim, Pei Jin; Stockdale, Lisa; Pinpathomrat, Nawamin; Bull, Naomi; Pasricha, Janet; Ulaszewska, Marta; Beglov, Yulia; Vaulont, Sophie; Drakesmith, Hal; McShane, Helen

Probabilistic data integration identifies reliable gametocyte-specific proteins and transcripts in malaria parasites. (2017) Meerstein-Kessel, Lisette; van der Lee, Robin; Stone, Will; Lanke, Kjerstin; Baker, David A; Alano, Pietro; Silvestrini, Francesco; Janse, Chris J; Khan, Shahid M; van de Vegte-Bolmer, Marga; Graumans, Wouter; Siebelink-Stoter, Rianne; Kooij, Taco WA; Marti, Matthias; Drakeley, Chris; Campo, Joseph J; van Dam, Teunis JP; Sauerwein, Robert; Bousema, Teun; Huynen, Martijn A

Safety of single low-dose primaquine in glucose-6-phosphate dehydrogenase deficient falciparum-infected African males: Two open-label, randomized, safety trials. (2017) Bastiaens, Guido JH; Tiono, Alfred B; Okebe, Joseph; Pett, Helmi E; Coulibaly, Sam A; Gonçalves, Bronner P; Affara, Muna; Ouédraogo, Alphonse; Bougouma, Edith C; Sanou, Guillaume S; Nébié, Issa; Bradley, John; Lanke, Kjerstin HW; Niemi, Mikko; Sirima, Sodiomon B; d'Alessandro, Umberto; Bousema, Teun; Drakeley, Chris

December 2017

The Human Infectious Reservoir of Falciparum Malaria. (2017) Goncalves, B

Relation between Skin Pharmacokinetics and Efficacy in AmBisome Treatment of Murine Cutaneous Leishmaniasis. (2017) Wijnant, Gert-Jan; Van Bocxlaer, Katrien; Yardley, Vanessa; Harris, Andy; Murdan, Sudaxshina; Croft, Simon L

A pilot study to understand feasibility and acceptability of stool and cord blood sample collection for a large-scale longitudinal birth cohort. (2017) Bailey, SR; Townsend, CL; Dent, H; Mallet, C; Tsaliki, E; Riley, EM; Noursadeghi, M; Lawley, TD; Rodger, AJ; Brocklehurst, P; Field, N

Detecting Gametocytes: How Sensitive Is Sensible? (2017) Meerstein-Kessel, Lisette; Bousema, Teun; Stone, Will

Team approach to manage difficult-to-treat TB cases: Experiences in Europe and beyond. (2017) D'Ambrosio, L; Bothamley, G; Caminero Luna, JA; Duarte, R; Guglielmetti, L; Muñoz Torrico, M; Payen, MC; Saavedra Herrera, N; Salazar Lezama, MA; Skrahina, A; Tadolini, M; Tiberi, S; Veziris, N; Migliori, GB

November 2017

Development of a non-human primate BCG infection model for the evaluation of candidate tuberculosis vaccines. (2017) Harris, Stephanie A; White, Andrew; Stockdale, Lisa; Tanner, Rachel; Sibley, Laura; Sarfas, Charlotte; Meyer, Joel; Peter, Jonathan; O'Shea, Matthew K; Manjaly Thomas, Zita-Rose; Hamidi, Ali; Satti, Iman; Dennis, Mike J; McShane, Helen; Sharpe, Sally

The Immunology of Wild Rodents: Current Status and Future Prospects. (2017) Viney, Mark; Riley, Eleanor M

October 2017

Comparative assessment of An. gambiae and An. stephensi mosquitoes to determine transmission-reducing activity of antibodies against P. falciparum sexual stage antigens. (2017) Eldering, Maarten; Bompard, Anaïs; Miura, Kazutoyo; Stone, Will; Morlais, Isabelle; Cohuet, Anna; van Gemert, Geert-Jan; Brock, Patrick M; Rijpma, Sanna R; van de Vegte-Bolmer, Marga; Graumans, Wouter; Siebelink-Stoter, Rianne; Da, Dari F; Long, Carole A; Morin, Merribeth J; Sauerwein, Robert W; Churcher, Thomas S; Bousema, Teun

IL-17 Production from T Helper 17, Mucosal-Associated Invariant T, and γδ Cells in Tuberculosis Infection and Disease. (2017) Coulter, Felicity; Parrish, Amy; Manning, Declan; Kampmann, Beate; Mendy, Joseph; Garand, Mathieu; Lewinsohn, David M; Riley, Eleanor M; Sutherland, Jayne S

September 2017

CMV and natural killer cells: shaping the response to vaccination. (2017) Goodier, Martin R; Jonjić, Stipan; Riley, Eleanor M; Juranić Lisnić, Vanda

Infection control, genetic assessment of drug resistance and drug susceptibility testing in the current management of multidrug/extensively-resistant tuberculosis (M/XDR-TB) in Europe: A tuberculosis network European Trialsgroup (TBNET) study. (2017) Bothamley, Graham H; Lange, Christoph; TBNET

Plasmodium berghei NK65 in Combination with IFN-γ Induces Endothelial Glucocorticoid Resistance via Sustained Activation of p38 and JNK. (2017) Zielińska, Karolina A; de Cauwer, Lode; Knoops, Sofie; Van der Molen, Kristof; Sneyers, Alexander; Thommis, Jonathan; De Souza, J Brian; Opdenakker, Ghislain; De Bosscher, Karolien; Van den Steen, Philippe E

Semi-high-throughput detection of Plasmodium falciparum and Plasmodium vivax oocysts in mosquitoes using bead-beating followed by circumsporozoite ELISA and quantitative PCR. (2017) Graumans, Wouter; Tadesse, Fitsum G; Andolina, Chiara; van Gemert, Geert-Jan; Teelen, Karina; Lanke, Kjerstin; Gadisa, Endalamaw; Yewhalaw, Delenasaw; van de Vegte-Bolmer, Marga; Siebelink-Stoter, Rianne; Reuling, Isaïe; Sauerwein, Robert; Bousema, Teun

August 2017

Impact of Helminth Infection on Antimycobacterial Immune Responses in UK Migrants. (2017) Anwar, S

Distinct activation mechanisms trigger the trypanocidal activity of DNA damaging prodrugs. (2017) Meredith, Emma Louise; Kumar, Ambika; Konno, Aya; Szular, Joanna; Alsford, Sam; Seifert, Karin; Horn, David; Wilkinson, Shane R

Naturally acquired antibody response to Plasmodium falciparum describes heterogeneity in transmission on islands in Lake Victoria. (2017) Idris, Zulkarnain Md; Chan, Chim W; Kongere, James; Hall, Tom; Logedi, John; Gitaka, Jesse; Drakeley, Chris; Kaneko, Akira

June 2017

Treatment of experimental visceral leishmaniasis with single-dose liposomal amphotericin B - pharmacodynamics and biodistribution at different stages of disease. (2017) Voak, AA; Harris, A; Qaiser, Z; Croft, SL; Seifert, K

Efficacy of Paromomycin-Chloroquine Combination Therapy in Experimental Cutaneous Leishmaniasis. (2017) Wijnant, Gert-Jan; Van Bocxlaer, Katrien; Yardley, Vanessa; Murdan, Sudaxshina; Croft, Simon L

May 2017

Malaria Host Candidate Genes Validated by Association With Current, Recent, and Historical Measures of Transmission Intensity. (2017) Sepúlveda, Nuno; Manjurano, Alphaxard; Campino, Susana G; Lemnge, Martha; Lusingu, John; Olomi, Raimos; Rockett, Kirk A; Hubbart, Christina; Jeffreys, Anna; Rowlands, Kate; Clark, Taane G; Riley, Eleanor M; Drakeley, Chris J; MalariaGEN Consortium

Resistance to malaria through structural variation of red blood cell invasion receptors. (2017) Leffler, Ellen M; Band, Gavin; Busby, George BJ; Kivinen, Katja; Le, Quang Si; Clarke, Geraldine M; Bojang, Kalifa A; Conway, David J; Jallow, Muminatou; Sisay-Joof, Fatoumatta; Bougouma, Edith C; Mangano, Valentina D; Modiano, David; Sirima, Sodiomon B; Achidi, Eric; Apinjoh, Tobias O; Marsh, Kevin; Ndila, Carolyne M; Peshu, Norbert; Williams, Thomas N; Drakeley, Chris; Manjurano, Alphaxard; Reyburn, Hugh; Riley, Eleanor; Kachala, David; Molyneux, Malcolm; Nyirongo, Vysaul; Taylor, Terrie; Thornton, Nicole; Tilley, Louise; Grimsley, Shane; Drury, Eleanor; Stalker, Jim; Cornelius, Victoria; Hubbart, Christina; Jeffreys, Anna E; Rowlands, Kate; Rockett, Kirk A; Spencer, Chris CA; Kwiatkowski, Dominic P; Malaria Genomic Epidemiology Network

7-Substituted 2-Nitro-5,6-dihydroimidazo[2,1-b][1,3]oxazines: Novel Antitubercular Agents Lead to a New Preclinical Candidate for Visceral Leishmaniasis. (2017) Thompson, AM; O'Connor, PD; Marshall, AJ; Yardley, V; Maes, L; Gupta, S; Launay, D; Braillard, S; Chatelain, E; Franzblau, SG; Wan, B; Wang, Y; Ma, Z; Cooper, CB; Denny, WA

The pPSU Plasmids for Generating DNA Molecular Weight Markers. (2017) Henrici, Ryan C; Pecen, Turner J; Johnston, James L; Tan, Song

Host Resistance to Plasmodium-Induced Acute Immune Pathology Is Regulated by Interleukin-10 Receptor Signaling. (2017) Claser, Carla; De Souza, J Brian; Thorburn, Samuel G; Grau, Georges Emile; Riley, Eleanor M; Rénia, Laurent; Hafalla, Julius CR

The comparative immunology of wild and laboratory mice, Mus musculus domesticus. (2017) Abolins, Stephen; King, Elizabeth C; Lazarou, Luke; Weldon, Laura; Hughes, Louise; Drescher, Paul; Raynes, John G; Hafalla, Julius CR; Viney, Mark E; Riley, Eleanor M

April 2017

Enhancement of cytokine-driven NK cell IFN-γ production after vaccination of HCMV infected Africans. (2017) Darboe, Alansana; Danso, Ebrima; Clarke, Ed; Umesi, Ama; Touray, Ebrima; Wegmuller, Rita; Moore, Sophie E; Riley, Eleanor M; Goodier, Martin R

Impact of metric and sample size on determining malaria hotspot boundaries. (2017) Stresman, Gillian H; Giorgi, Emanuele; Baidjoe, Amrish; Knight, Phil; Odongo, Wycliffe; Owaga, Chrispin; Shagari, Shehu; Makori, Euniah; Stevenson, Jennifer; Drakeley, Chris; Cox, Jonathan; Bousema, Teun; Diggle, Peter J

March 2017

Natural Killer cell function after vaccination in an African (Gambian) population. (2017) Darboe, A

A proteasome inhibitor produced by Burkholderia pseudomallei modulates intracellular growth. (2017) Wagley, S; Vanaporn, M; Rinchai, D; Conejero, L; Lertmemongkolchai, G; Bancroft, GJ; Titball, RW

Age, Weight, and CYP2D6 Genotype Are Major Determinants of Primaquine Pharmacokinetics in African Children. (2017) Gonçalves, Bronner P; Pett, Helmi; Tiono, Alfred B; Murry, Daryl; Sirima, Sodiomon B; Niemi, Mikko; Bousema, Teun; Drakeley, Chris; Ter Heine, Rob

Pregnant Women: An Overlooked Asset to Plasmodium falciparum Malaria Elimination Campaigns? (2017) Gonçalves, Bronner P; Walker, Patrick G; Cairns, Matthew; Tiono, Alfred B; Bousema, Teun; Drakeley, Chris

A quantitative brain map of experimental cerebral malaria pathology. (2017) Strangward, Patrick; Haley, Michael J; Shaw, Tovah N; Schwartz, Jean-Marc; Greig, Rachel; Mironov, Aleksandr; de Souza, J Brian; Cruickshank, Sheena M; Craig, Alister G; Milner, Danny A; Allan, Stuart M; Couper, Kevin N

The shape of the iceberg: quantification of submicroscopic Plasmodium falciparum and Plasmodium vivax parasitaemia and gametocytaemia in five low endemic settings in Ethiopia. (2017) Tadesse, Fitsum G; van den Hoogen, Lotus; Lanke, Kjerstin; Schildkraut, Jodie; Tetteh, Kevin; Aseffa, Abraham; Mamo, Hassen; Sauerwein, Robert; Felger, Ingrid; Drakeley, Chris; Gadissa, Endalamaw; Bousema, Teun

NK Cells: Uncertain Allies against Malaria. (2017) Wolf, Asia-Sophia; Sherratt, Samuel; Riley, Eleanor M

February 2017

Determinants of Malaria Transmission at the Population Level. (2017) Bousema, Teun; Drakeley, Chris

The UK ME/CFS Biobank for biomedical research on Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and Multiple Sclerosis. (2017) Lacerda, Eliana M; Bowman, Erinna W; Cliff, Jacqueline M; Kingdon, Caroline C; King, Elizabeth C; Lee, Ji-Sook; Clark, Taane G; Dockrell, Hazel M; Riley, Eleanor M; Curran, Hayley; Nacul, Luis

Contribution of Plasmodium knowlesi to Multispecies Human Malaria Infections in North Sumatera, Indonesia. (2017) Lubis, Inke ND; Wijaya, Hendri; Lubis, Munar; Lubis, Chairuddin P; Divis, Paul CS; Beshir, Khalid B; Sutherland, Colin J

January 2017

Dose-dependent effect and pharmacokinetics of fexinidazole and its metabolites in a mouse model of human african trypanosomiasis. (2017) Burrell-Saward, H; Harris, AJ; de LaFlor, R; Sallam, H; Alavijeh, MS; Ward, TH; Croft, SL

Synthesis and antitrypanosomal activities of novel pyridylchalcones. (2017) Bhambra, AS; Ruparelia, KC; Tan, HL; Tasdemir, D; Burrell-Saward, H; Yardley, V; Beresford, KJ; Arroo, RR

Natural killer cell responses to Plasmodium falciparum-infected red blood cells. (2017) Wolf, AS

2017

The Tuberculosis Network European Trials Group (TBNET): new directions in the management of tuberculosis. (2017) Bothamley, Graham

Molecular Markers for Sensitive Detection of Plasmodium falciparum Asexual Stage Parasites and their Application in a Malaria Clinical Trial. (2017) Tadesse, Fitsum G; Lanke, Kjerstin; Nebie, Issa; Schildkraut, Jodie A; Gonçalves, Bronner P; Tiono, Alfred B; Sauerwein, Robert; Drakeley, Chris; Bousema, Teun; Rijpma, Sanna R