Items where Faculty or Department is "Department of Infection Biology"
LSHTM Organisational Structure (62309)
Faculty of Infectious and Tropical Diseases (19963)
Department of Infection Biology (5999)
Dept of Immunology and Infection (-2019) (955)
Dept of Pathogen Molecular Biology (-2019) (1083)
Number of items: 96.
December 2024
Plasmodium knowlesi Infection Is Associated With Elevated Circulating Biomarkers of Brain Injury and Endothelial Activation. (2024)
Bertran-Cobo, Cesc; Dumont, Elin; Noordin, Naqib Rafieqin; Lai, Meng-Yee; Stone, William; Tetteh, Kevin KA; Drakeley, Chris; Krishna, Sanjeev; Lau, Yee-Ling; Wassmer, Samuel C
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A potent and selective reaction hijacking inhibitor of Plasmodium falciparum tyrosine tRNA synthetase exhibits single dose oral efficacy in vivo. (2024)
Xie, Stanley C; Tai, Chia-Wei; Morton, Craig J; Ma, Liting; Huang, Shih-Chung; Wittlin, Sergio; Du, Yawei; Hu, Yongbo; Dogovski, Con; Salimimarand, Mina; Griffin, Robert; England, Dylan; de la Cruz, Elisa; Deni, Ioanna; Yeo, Tomas; Burkhard, Anna Y; Striepen, Josefine; Schindler, Kyra A; Crespo, Benigno; Gamo, Francisco J; Khandokar, Yogesh; Hutton, Craig A; Rabie, Tayla; Birkholtz, Lyn-Marié; Famodimu, Mufuliat T; Delves, Michael J; Bolsher, Judith; Koolen, Karin MJ; van der Laak, Rianne; Aguiar, Anna CC; Pereira, Dhelio B; Guido, Rafael VC; Creek, Darren J; Fidock, David A; Dick, Lawrence R; Brand, Stephen L; Gould, Alexandra E; Langston, Steven; Griffin, Michael DW; Tilley, Leann
Asymptomatic Plasmodium falciparum infections and determinants of carriage in a seasonal malaria chemoprevention setting in Northern Cameroon and south Senegal (Kedougou). (2024)
Ali, Innocent M; Manga, Isaac A; Nji, Akindeh M; Tchuenkam, Valery P; Neba, Peter Thelma Ngwa; Achu, Dorothy F; Bigoga, Jude D; Faye, Babacar; Roper, Cally; Sutherland, Colin J; Mbacham, Wilfred F
Dataset of 16S rRNA gene sequences of 111 healthy and Newcastle disease infected caecal samples from multiple chicken breeds of Pakistan. (2024)
Ameer, Aqsa; Saleem, Farrukh; Keating, Ciara; Gundogdu, Ozan; Ijaz, Umer Zeeshan; Javed, Sundus
Whole-genome sequencing surveillance of Siberian tick-borne encephalitis virus (TBEV) identifies an additional lineage in Kyrgyzstan. (2024)
D'Addiego, Jake; Curran-French, Mollie; Smith, Jack; Junushov, Asankadyr T; Breininger, Irena; Atkinson, Barry; Hay, John; Hewson, Roger
The genomic diversity and antimicrobial resistance of Non-typhoidal Salmonella in humans and food animals in Northern India. (2024)
Mahindroo, Jaspreet; Thanh, Duy Pham; Kaur, Harpreet; To Nguyen Thi Nguyen; Nguyen, Trang Hoang Thu; Carey, Megan E; Verma, Ritu; Mohan, Balvinder; Thakur, Siddhartha; Baker, Stephen; Taneja, Neelam
Boosting Vaccine Research: The 16-Year Journey of TRANSVAC Vaccine Infrastructure. (2024)
Martin, William; Luís, Catarina; Jungbluth, Stefan; Slezak, Monika; Verreck, Frank AW; Spiegel, Holger; Guzman, Carlos A; Roldão, António; Carrondo, Manuel JT; Van der Ley, Peter; Segalés, Joaquim; Dockrell, Hazel M; Ho, Mei Mei; Pedersen, Gabriel K; Lawrenz, Maria; Olesen, Ole F
IMC1g knockdowns reveal malaria blood-stage alveolin functions. (2024)
Tremp, Annie Z; Saeed, Sadia; Dessens, Johannes T
Expediting pathogen genomics adoption for enhanced foodborne disease surveillance in Africa. (2024)
Kanzi, Aquillah M; Smith, Stella I; Msefula, Chisomo; Mwaba, John; Ajayi, Abraham; Kwenda, Geoffrey; Tanui, Collins K; Smith, Anthony M; Bester, Linda A; Derra, Firehiwot A; Yamba, Kaunda; Banda, Daniel L; Kalule, John B; Kumburu, Happiness H; Fakim, Yasmina J; Sithole, Nyasha; Njage, Patrick MK; Chikuse, Francis F; Ondoa, Pascale; Tessema, Sofonias K; Foster-Nyarko, Ebenezer
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Safety and efficacy of the blood-stage malaria vaccine RH5.1/Matrix-M in Burkina Faso: interim results of a double-blind, randomised, controlled, phase 2b trial in children. (2024)
Natama, Hamtandi M; Salkeld, Jo; Somé, Athanase; Soremekun, Seyi; Diallo, Salou; Traoré, Ousmane; Rouamba, Toussaint; Ouédraogo, Florence; Ouédraogo, Edouard; Daboné, K Carine Sonia; Koné, Nadine A; Compaoré, Z Michael John; Kafando, Miguel; Bonko, Massa Dit Achille; Konaté, Fabé; Sorgho, Hermann; Nielsen, Carolyn M; Pipini, Dimitra; Diouf, Ababacar; King, Lloyd DW; Shaligram, Umesh; Long, Carole A; Cho, Jee-Sun; Lawrie, Alison M; Skinner, Katherine; Roberts, Rachel; Miura, Kazutoyo; Bradley, John; Silk, Sarah E; Draper, Simon J; Tinto, Halidou; Minassian, Angela M
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Identification of complex Plasmodium falciparum genetic backgrounds circulating in Africa: a multicountry genomic epidemiology analysis. (2024)
Miotto, Olivo; Amambua-Ngwa, Alfred; Amenga-Etego, Lucas N; Abdel Hamid, Muzamil M; Adam, Ishag; Aninagyei, Enoch; Apinjoh, Tobias; Awandare, Gordon A; Bejon, Philip; Bertin, Gwladys I; Bouyou-Akotet, Marielle; Claessens, Antoine; Conway, David J; D'Alessandro, Umberto; Diakite, Mahamadou; Djimdé, Abdoulaye; Dondorp, Arjen M; Duffy, Patrick; Fairhurst, Rick M; Fanello, Caterina I; Ghansah, Anita; Ishengoma, Deus S; Lawniczak, Mara; Maïga-Ascofaré, Oumou; Auburn, Sarah; Rosanas-Urgell, Anna; Wasakul, Varanya; White, Nina FD; Harrott, Alexandria; Almagro-Garcia, Jacob; Pearson, Richard D; Goncalves, Sonia; Ariani, Cristina; Bozdech, Zbynek; Hamilton, William L; Simpson, Victoria; Kwiatkowski, Dominic P
November 2024
Antibody and T-cell responses in rotavirus vaccinated Zambian infants: impact of human cytomegalovirus infection. (2024)
Laban, NM
Transmissibility and antimalarial resistance in human malaria parasite
Plasmodium falciparum in Mali. (2024)
Vanheer, LN
Non-typhoidal Salmonella in humans in India, Vietnam, Bangladesh and Sri Lanka: a systematic review. (2024)
Raju, Reshma; O'Neil, Luke; Kerr, Charlotte; Lehri, Burhan; Sarkar, Sudipta; Soni, Twinkle; Nguipdop-Djomo, Patrick; Conan, Anne; Tu, Nguyen Dong; Hung, Tran Thi Mai; Hay, Melanie; Falconer, Jane; Tomley, Fiona; Blake, Damer; Fournié, Guillaume; Ajjampur, Sitara Swarna Rao; Mangtani, Punam; Stabler, Richard
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A Pangenotypic Hepatitis E Virus Replication Inhibitor With High Potency in a Rat Infection Model. (2024)
Zhang, Xin; Klöhn, Mara; Ouwerkerk-Mahadevan, Sivi; Jagst, Michelle; Vereyken, Liesbeth; Verboven, Peter; Goovaerts, Quinten; Todt, Daniel; Jonckers, Tim HM; Coelmont, Lotte; Fletcher, Helen; Das, Kalyan; Samby, Kirandeep; Neyts, Johan; Steinmann, Eike; Koul, Anil; Kaptein, Suzanne JF
Adjunctive ivermectin mass drug administration for malaria control on the Bijagos Archipelago of Guinea-Bissau (MATAMAL): a quadruple-blinded, cluster-randomised, placebo-controlled trial. (2024)
Hutchins, Harry; Pretorius, Elizabeth; Bradley, John; Teixeira da Silva, Eunice; Vasileva, Hristina; Ndiath, Mamadou Ousmane; Jones, Robert T; Soumare, Harouna Dit Massire; Nyang, Haddy; Prom, Aurelia; Sambou, Sarata; Ceesay, Fatima; Ceesay, Sainey; Moss, Sophie; Mabey, David; Djata, Paulo; Nante, Jose Ernesto; Martins, Cesario; Logan, James G; Slater, Hannah; Tetteh, Kevin; Drakeley, Chris; D'Alessandro, Umberto; Rodrigues, Amabelia; Last, Anna
Animal models for exploring Chagas disease pathogenesis and supporting drug discovery. (2024)
Khan, Archie A; Taylor, Martin C; Fortes Francisco, Amanda; Jayawardhana, Shiromani; Atherton, Richard L; Olmo, Francisco; Lewis, Michael D; Kelly, John M
Tambjamines as Fast-Acting Multistage Antimalarials. (2024)
Kumar, Amrendra; Li, Yuexin; Dodean, Rozalia A; Roth, Alison; Caridha, Diana; Madejczyk, Michael S; Jin, Xiannu; Dennis, William E; Lee, Patricia J; Pybus, Brandon S; Martin, Monica; Pannone, Kristina; Dinh, Hieu T; Blount, Cameron; Chetree, Ravi; DeLuca, Jesse; Evans, Martin; Nadeau, Robert; Vuong, Chau; Leed, Susan; Black, Chad; Sousa, Jason; Nolan, Christina; Ceja, Frida G; Rasmussen, Stephanie A; Tumwebaze, Patrick K; Rosenthal, Philip J; Cooper, Roland A; Rottmann, Matthias; Orjuela-Sanchez, Pamela; Meister, Stephan; Winzeler, Elizabeth A; Delves, Michael J; Matthews, Holly; Baum, Jake; Kirby, Robert W; Burrows, Jeremy N; Duffy, James; Peyton, David H; Reynolds, Kevin A; Kelly, Jane X; Kancharla, Papireddy
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October 2024
Diversity, functional classification and genotyping of SHV β-lactamases in Klebsiella pneumoniae. (2024)
Tsang, Kara K; Lam, Margaret MC; Wick, Ryan R; Wyres, Kelly L; Bachman, Michael; Baker, Stephen; Barry, Katherine; Brisse, Sylvain; Campino, Susana; Chiaverini, Alexandra; Cirillo, Daniela Maria; Clark, Taane; Corander, Jukka; Corbella, Marta; Cornacchia, Alessandra; Cuénod, Aline; D'Alterio, Nicola; Di Marco, Federico; Donado-Godoy, Pilar; Egli, Adrian; Farzana, Refath; Feil, Edward J; Fostervold, Aasmund; Gorrie, Claire L; Hassan, Brekhna; Hetland, Marit Andrea Klokkhammer; Hoa, Le Nguyen Minh; Hoi, Le Thi; Howden, Benjamin; Ikhimiukor, Odion O; Jenney, Adam WJ; Kaspersen, Håkon; Khokhar, Fahad; Leangapichart, Thongpan; Ligowska-Marzęta, Małgorzata; Löhr, Iren Høyland; Long, Scott W; Mathers, Amy J; McArthur, Andrew G; Nagaraj, Geetha; Oaikhena, Anderson O; Okeke, Iruka N; Perdigão, João; Parikh, Hardik; Pham, My H; Pomilio, Francesco; Raffelsberger, Niclas; Rakotondrasoa, Andriniaina; Kumar, KL Ravi; Roberts, Leah W; Rodrigues, Carla; Samuelsen, Ørjan; Sands, Kirsty; Sassera, Davide; Seth-Smith, Helena; Shamanna, Varun; Sherry, Norelle L; Sia, Sonia; Spadar, Anton; Stoesser, Nicole; Sunde, Marianne; Sundsfjord, Arnfinn; Thach, Pham Ngoc; Thomson, Nicholas R; Thorpe, Harry A; Torok, M Estée; Trang, Van Dinh; Trung, Nguyen Vu; Vornhagen, Jay; Walsh, Timothy; Warne, Ben; Wilson, Hayley; Wright, Gerard D; Holt, Kathryn E; KlebNET-Gsp Amr Genotype-Phenotype Group
Surveillance of travel-associated isolates elucidates the diversity of non-pandemic Vibrio cholerae. (2024)
Bote, Lia; Taylor-Brown, Alyce; Maes, Mailis; Ingle, Danielle J; Valcanis, Mary; Howden, Benjamin P; Thomson, Nicholas R
Diversity of Chagas disease diagnostic antigens: Successes and limitations. (2024)
Bhattacharyya, Tapan; Murphy, Niamh; Miles, Michael A
Characterisation of Neisseria gonorrhoeae strain differences in patients with multisite infection. (2024)
Miari, Victoria F; Blakiston, Matthew R; Solanki, Priya; Gundogdu, Ozan; Stabler, Richard A
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Phenotypic evidence of deltamethrin resistance and identification of selective sweeps in Anopheles mosquitoes on the Bijagós Archipelago, Guinea-Bissau. (2024)
Moss, Sophie; Jones, Robert T; Pretorius, Elizabeth; da Silva, Eunice Teixeira; Higgins, Matthew; Kristan, Mojca; Acford-Palmer, Holly; Collins, Emma L; Rodrigues, Amabelia; Krishna, Sanjeev; Clark, Taane G; Last, Anna; Campino, Susana
Exploration and characterization of the antimalarial activity of cyclopropyl carboxamides that target the mitochondrial protein, cytochrome b. (2024)
Awalt, Jon Kyle; Su, Wenyin; Nguyen, William; Loi, Katie; Jarman, Kate E; Penington, Jocelyn S; Ramesh, Saishyam; Fairhurst, Kate J; Yeo, Tomas; Park, Heekuk; Uhlemann, Anne-Catrin; Chandra Maity, Bikash; De, Nirupam; Mukherjee, Partha; Chakraborty, Arnish; Churchyard, Alisje; Famodimu, Mufuliat T; Delves, Michael J; Baum, Jake; Mittal, Nimisha; Winzeler, Elizabeth A; Papenfuss, Anthony T; Chowdury, Mrittika; de Koning-Ward, Tania F; Maier, Alexander G; van Dooren, Giel G; Baud, Delphine; Brand, Stephen; Fidock, David A; Jackson, Paul F; Cowman, Alan F; Dans, Madeline G; Sleebs, Brad E
Diagnostic Performance of Unstimulated IFN-γ (IRISA-TB) for Pleural Tuberculosis: A Prospective Study in South Africa and India. (2024)
Christopher, Devasahayam J; Esmail, Aliasgar; Scott, Alex J; Wilson, Lindsay; Randall, Philippa; Thangakunam, Balamugesh; Shankar, Deepa; Rajasekar, Sekar; Christudass, Christhunesa S; Kühn, Louié; Swanepoel, Jeremi; Perumal, Tahlia; Pooran, Anil; Oelofse, Suzette; Dheda, Keertan
Newly Identified Mycobacterium africanum Lineage 10, Central Africa. (2024)
Guyeux, Christophe; Senelle, Gaetan; Le Meur, Adrien; Supply, Philip; Gaudin, Cyril; Phelan, Jody E; Clark, Taane G; Rigouts, Leen; de Jong, Bouke; Sola, Christophe; Refrégier, Guislaine
Molecular Epidemiology and AMR Perspective of Diarrhoeagenic Escherichia coli in Africa: A Systematic Review and Meta-analysis. (2024)
Kalule, John Bosco; Bester, Linda A; Banda, Daniel L; Derra, Firehiwot Abera; Msefula, Chisomo; Smith, Anthony M; Ajayi, Abraham; Kumburu, Happiness; Kwenda, Geoffrey; Yamba, Kaunda; Mwaba, John; Fakim, Yasmina J; Sithole, Nyasha; Kanzi, Aquillah M; Njage, Patrick MK; Chikuse, Francis; Tessema, Sofonias K; Smith, Stella I; Foster-Nyarko, Ebenezer
Serological analysis in humans in Malaysian Borneo suggests prior exposure to H5 avian influenza near migratory shorebird habitats. (2024)
Klim, Hannah; William, Timothy; Mellors, Jack; Brady, Caolann; Rajahram, Giri S; Chua, Tock H; Brazal Monzó, Helena; John, Jecelyn Leslie; da Costa, Kelly; Jeffree, Mohammad Saffree; Temperton, Nigel J; Tipton, Tom; Thompson, Craig P; Ahmed, Kamruddin; Drakeley, Chris J; Carroll, Miles W; Fornace, Kimberly M
Plasmodium falciparum protein phosphatase PP7 is required for early ring-stage development. (2024)
Patel, Avnish; Fréville, Aline; Rey, Joshua A; Flynn, Helen R; Koussis, Konstantinos; Skehel, Mark J; Blackman, Michael J; Baker, David A
An open-access dashboard to interrogate the genetic diversity of Mycobacterium tuberculosis clinical isolates. (2024)
Phelan, Jody; Van den Heede, Klaas; Masyn, Serge; Verbeeck, Rudi; Clark, Taane G; Lamprecht, Dirk A; Koul, Anil; Wall, Richard J
Essential role of proline synthesis and the one-carbon metabolism pathways for systemic virulence of Streptococcus pneumoniae. (2024)
Ramos-Sevillano, Elisa; Ercoli, Giuseppe; Betts, Modupeh; Guerra-Assunção, José Afonso; Iverson, Amy; Frank, Matthew; Partridge, Frederick; Lo, Stephanie W; Fernandes, Vitor E; Nasher, Fauzy; Wall, Emma; Wren, Brendan; Gordon, Stephen B; Ferreira, Daniela M; Heyderman, Rob; Rosch, Jason; Brown, Jeremy S
Brazil towards malaria elimination: A time-series analysis of imported cases from 2007 to 2022. (2024)
Garcia, Klauss Kleydmann Sabino; Laporta, Gabriel Z; Soremekun, Seyi; Bottomley, Christian; Abrahão, Amanda Amaral; Moresco, Gilberto Gilmar; Drakeley, Chris; Costa, Anielle de Pina; Siqueira, André M
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September 2024
Multi-omics analysis reveals regime shifts in the gastrointestinal ecosystem in chickens following anticoccidial vaccination and Eimeria tenella challenge. (2024)
Liu, Po-Yu; Liaw, Janie; Soutter, Francesca; Ortiz, José Jaramillo; Tomley, Fiona M; Werling, Dirk; Gundogdu, Ozan; Blake, Damer P; Xia, Dong
Impact of VP2 structure on antigenicity: comparison of BTV1 and the highly virulent BTV8 serotype. (2024)
Bissett, Sara L; Roy, Polly
Development of targeted whole genome sequencing approaches for Crimean-Congo haemorrhagic fever virus (CCHFV). (2024)
D'Addiego, Jake; Shah, Sonal; Pektaş, Ayşe Nur; Bağci, Bi Nnur Köksal; Öz, Murtaza; Sebastianelli, Sasha; Elaldı, Nazif; Allen, David J; Hewson, Roger
HuR (ELAVL1) regulates the CCHFV minigenome and HAZV replication by associating with viral genomic RNA. (2024)
Ikegawa, Moe; Kano, Norisuke; Ori, Daisuke; Fukuta, Mizuki; Hirano, Minato; Hewson, Roger; Yoshii, Kentaro; Kawai, Taro; Kawasaki, Takumi
Parasite clearance and protection from Plasmodium falciparum infection (PCPI): a three-arm, parallel, double-blinded, placebo-controlled, randomised trial of presumptive sulfadoxine-pyrimethamine versus sulfadoxine-pyrimethamine plus amodiaquine versus artesunate monotherapy among asymptomatic children 3-5 years of age in Cameroon. (2024)
Martinez-Vega, Rosario; Mbacham, Wilfred Fon; Ali, Innocent; Nji, Akindeh; Mousa, Andria; Beshir, Khalid B; Chopo-Pizarro, Ana; Kaur, Harparkash; Okell, Lucy; Hansson, Helle; Hocke, Emma Filtenborg; Alifrangis, Michael; Gosling, Roland; Roper, Cally; Sutherland, Colin; Chico, R Matthew
Whole genome sequence analysis of population structure and insecticide resistance markers in Anopheles melas from the Bijagós Archipelago, Guinea-Bissau. (2024)
Moss, Sophie; Pretorius, Elizabeth; Ceesay, Sainey; da Silva, Eunice Teixeira; Hutchins, Harry; Ndiath, Mamadou Ousmane; Acford-Palmer, Holly; Collins, Emma L; Higgins, Matthew; Phelan, Jody; Jones, Robert T; Vasileva, Hristina; Rodrigues, Amabelia; Krishna, Sanjeev; Clark, Taane G; Last, Anna; Campino, Susana
Real-time estimation of immunological responses against emerging SARS-CoV-2 variants in the UK: a mathematical modelling study. (2024)
Russell, Timothy W; Townsley, Hermaleigh; Hellewell, Joel; Gahir, Joshua; Shawe-Taylor, Marianne; Greenwood, David; Hodgson, David; Hobbs, Agnieszka; Dowgier, Giulia; Penn, Rebecca; Sanderson, Theo; Stevenson-Leggett, Phoebe; Bazire, James; Harvey, Ruth; Fowler, Ashley S; Miah, Murad; Smith, Callie; Miranda, Mauro; Bawumia, Philip; Mears, Harriet V; Adams, Lorin; Hatipoglu, Emine; O'Reilly, Nicola; Warchal, Scott; Ambrose, Karen; Strange, Amy; Kelly, Gavin; Kjar, Svend; Papineni, Padmasayee; Corrah, Tumena; Gilson, Richard; Libri, Vincenzo; Kassiotis, George; Gamblin, Steve; Lewis, Nicola S; Williams, Bryan; Swanton, Charles; Gandhi, Sonia; Beale, Rupert; Wu, Mary Y; Bauer, David LV; Carr, Edward J; Wall, Emma C; Kucharski, Adam J
Post-transcriptional reprogramming by thousands of mRNA untranslated regions in trypanosomes. (2024)
Trenaman, Anna; Tinti, Michele; Wall, Richard J; Horn, David
August 2024
Lactam Truncation Yields a Dihydroquinazolinone Scaffold with Potent Antimalarial Activity that Targets PfATP4. (2024)
Ashton, Trent D; Calic, Petar PS; Dans, Madeline G; Kang Ooi, Zi; Zhou, Qingmiao; Loi, Katie; Jarman, Kate E; Palandri, Josephine; Qiu, Deyun; Lehane, Adele M; Maity, Bikash; De, Nirupam; Famodimu, Mufuliat T; Delves, Michael J; Mao, Emma Y; Gancheva, Maria R; Wilson, Danny W; Chowdury, Mrittika; de Koning-Ward, Tania F; Baud, Delphine; Brand, Stephen; Jackson, Paul F; Cowman, Alan F; Sleebs, Brad E
A Pan Plasmodium lateral flow recombinase polymerase amplification assay for monitoring malaria parasites in vectors and human populations. (2024)
Higgins, Matthew; Kristan, Mojca; Collins, Emma L; Messenger, Louisa A; Dombrowski, Jamille G; Vanheer, Leen N; Nolder, Debbie; Drakeley, Christopher J; Stone, William; Mahamar, Almahamoudou; Bousema, Teun; Delves, Michael; Bandibabone, Janvier; N'Do, Sévérin; Bantuzeko, Chimanuka; Zawadi, Bertin; Walker, Thomas; Sutherland, Colin J; Marinho, Claudio RF; Cameron, Mary M; Clark, Taane G; Campino, Susana
WHO global research priorities for antimicrobial resistance in human health. (2024)
Bertagnolio, Silvia; Dobreva, Zlatina; Centner, Chad M; Olaru, Ioana Diana; Donà, Daniele; Burzo, Stefano; Huttner, Benedikt D; Chaillon, Antoine; Gebreselassie, Nebiat; Wi, Teodora; Hasso-Agopsowicz, Mateusz; Allegranzi, Benedetta; Sati, Hatim; Ivanovska, Verica; Kothari, Kavita U; Balkhy, Hanan H; Cassini, Alessandro; Hamers, Raph L; Weezenbeek, Kitty Van; WHO Research Agenda for AMR in Human Health Collaborators
Adaptation and validation of a light microscope for use in energy insecure settings: a proof-of-concept study. (2024)
Bühler, Nina; Velten, Diana; Jung, Philipp; Müller, Sophie E; Becker, Sören L; Burza, Sakib; Schneitler, Sophie
Recruitment of multi-segment genomic RNAs by Bluetongue virus requires a preformed RNA network. (2024)
Sung, Po-Yu; Phelan, Jody E; Luo, Dongsheng; Kulasegaran-Shylini, Raghavendran; Bohn, Patrick; Smyth, Redmond P; Roy, Polly
Whole genome sequencing analysis of Mycobacterium tuberculosis reveals circulating strain types and drug-resistance mutations in the Philippines. (2024)
Wang, Linfeng; Lim, Dodge R; Phelan, Jody E; Reyes, Lorenzo T; Palparan, Alma G; Sanchez, Maria Guileane C; Asuncion, Louella Abigail A; Tujan, Ma Angelica A; Medado, Inez Andrea P; Daga, Chona Mae A; Llames, Jo-Hannah S; Mitarai, Satoshi; Murase, Yoshiro; Morishige, Yuta; Ang, Concepcion F; Malabad, John Carlo M; Montoya, Jaime C; Hafalla, Julius C; Campino, Susana; Hibberd, Martin L; Ama, Cecilia G; Basilio, Ramon P; La Paz, Eva Maria Cutiongoco-De; Clark, Taane G
July 2024
Development of Rapid Diagnostic Tests for Trypanosoma cruzi Lineage-Specific Serology, Comparative Epidemiology and for Monitoring Efficacy of Chemotherapy. (2024)
Murphy, N
Pathogen diversity and antimicrobial resistance transmission of Salmonella enterica serovars Typhi and Paratyphi A in Bangladesh, Nepal, and Malawi: a genomic epidemiological study. (2024)
Dyson, Zoe A; Ashton, Philip M; Khanam, Farhana; Chunga Chirambo, Angeziwa; Shakya, Mila; Meiring, James E; Tonks, Susan; Karkey, Abhilasha; Msefula, Chisomo; Clemens, John D; Dunstan, Sarah J; Baker, Stephen; Dougan, Gordon; Pitzer, Virginia E; Basnyat, Buddha; Qadri, Firdausi; Heyderman, Robert S; Gordon, Melita A; Pollard, Andrew J; Holt, Kathryn E; STRATAA Study Group
Could prophylactic antivirals reduce dengue incidence in a high-prevalence endemic area? (2024)
Jafari, Yalda; Brady, Oliver J; Biggs, Joseph R; Lien, Le Thuy; Mai, Huynh Kim; Nguyen, Hien Anh Thi; Van Loock, Marnix; Herrera-Taracena, Guillermo; Menten, Joris; Iwasaki, Chihiro; Takegata, Mizuki; Kitamura, Noriko; Do Thai, Hung; Minh, Bui Xuan; Morita, Kouichi; Anh, Dang Duc; Clifford, Sam; Prem, Kiesha; Hafalla, Julius; Edmunds, W John; Yoshida, Lay Myint; Hibberd, Martin L; Hué, Stéphane
Artemether-lumefantrine with or without single-dose primaquine and sulfadoxine-pyrimethamine plus amodiaquine with or without single-dose tafenoquine to reduce Plasmodium falciparum transmission: a phase 2, single-blind, randomised clinical trial in Ouelessebougou, Mali. (2024)
Mahamar, Almahamoudou; Smit, Merel J; Sanogo, Koualy; Sinaba, Youssouf; Niambele, Sidi M; Sacko, Adama; Dicko, Oumar M; Diallo, Makonon; Maguiraga, Seydina O; Sankaré, Yaya; Keita, Sekouba; Samake, Siaka; Dembele, Adama; Lanke, Kjerstin; Ter Heine, Rob; Bradley, John; Dicko, Yahia; Traore, Sekou F; Drakeley, Chris; Dicko, Alassane; Bousema, Teun; Stone, Will
Effect of weekly fever-screening and treatment and monthly RDT testing and treatment on the infectious reservoir of malaria parasites in Burkina Faso: a cluster-randomised trial. (2024)
Collins, Katharine A; Ouedraogo, Alphonse; Guelbeogo, Wamdaogo Moussa; Soulama, Issiaka; Ouattara, Maurice S; Sombie, Salif; Ouedraogo, Nicolas; Coulibaly, Aboubacar S; Nombre, Apollinaire; Lanke, Kjerstin; Ramjith, Jordache; Awandu, Shehu S; Serme, Samuel S; Henry, Noelie; Stone, Will; Ouedraogo, Issa N; Diarra, Amidou; Holden, Tobias M; Sirima, Sodiomon B; Bradley, John; Soremekun, Seyi; Selvaraj, Prashanth; Gerardin, Jaline; Drakeley, Chris; Bousema, Teun; Tiono, Alfred B
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June 2024
Activation loop phosphorylation and cGMP saturation of PKG regulate egress of malaria parasites. (2024)
Koussis, Konstantinos; Haase, Silvia; Withers-Martinez, Chrislaine; Flynn, Helen R; Kunzelmann, Simone; Christodoulou, Evangelos; Ibrahim, Fairouz; Skehel, Mark; Baker, David A; Blackman, Michael J
Dynamics of Trypanosoma cruzi infection in hamsters and novel association with progressive motor dysfunction. (2024)
Langston, Harry; Fortes Francisco, Amanda; Doidge, Ciaran; Roberts, Chrissy H; Khan, Archie A; Jayawardhana, Shiromani; Taylor, Martin C; Kelly, John M; Lewis, Michael D
Uncovering the genetic diversity in Aedes aegypti insecticide resistance genes through global comparative genomics. (2024)
Spadar, Anton; Collins, Emma; Messenger, Louisa A; Clark, Taane G; Campino, Susana
Estimating the Impact of DHPS Mutations on Sulfadoxine-Pyrimethamine Protective Efficacy: A Pooled Analysis of Individual Patient Data and Implications for Malaria Chemoprevention in Sub-Saharan Africa. (2024)
Mousa, Andria; Cuomo-Dannenburg, Gina; Thompson, Hayley A; Bell, David J; D'Alessandro, Umberto; Gosling, Roly; Nahum, Alain; Barnes, Karen; Raman, Jaishree; Workman, Lesley; Foo, Yong See; Flegg, Jennifer; Hocke, Emma F; Hansson, Helle; Chopo-Pizarro, Ana; Beshir, Khalid B; Alifrangis, Michael; Chico, R Matthew; Sutherland, Colin J; Okell, Lucy; Roper, Cally
Genome Sequences of Extended-Spectrum Beta-Lactamase-Producing Escherichia coli Recovered from Mid-Stream Urine Samples in Accra, Ghana. (2024)
Dayie, Nicholas TKD; Egyir, Beverly; Amoa-Owusu, Felicia; Owusu-Nyantakyi, Christian; Adu, Bright; Kotey, Fleischer CN; Donkor, Eric S; Stabler, Richard A
Aryl amino acetamides prevent Plasmodium falciparum ring development via targeting the lipid-transfer protein PfSTART1. (2024)
Dans, Madeline G; Boulet, Coralie; Watson, Gabrielle M; Nguyen, William; Dziekan, Jerzy M; Evelyn, Cindy; Reaksudsan, Kitsanapong; Mehra, Somya; Razook, Zahra; Geoghegan, Niall D; Mlodzianoski, Michael J; Goodman, Christopher Dean; Ling, Dawson B; Jonsdottir, Thorey K; Tong, Joshua; Famodimu, Mufuliat Toyin; Kristan, Mojca; Pollard, Harry; Stewart, Lindsay B; Brandner-Garrod, Luke; Sutherland, Colin J; Delves, Michael J; McFadden, Geoffrey I; Barry, Alyssa E; Crabb, Brendan S; de Koning-Ward, Tania F; Rogers, Kelly L; Cowman, Alan F; Tham, Wai-Hong; Sleebs, Brad E; Gilson, Paul R
Plasmodium LCCL domain-containing modular proteins have their origins in the ancestral alveolate. (2024)
De Hoest-Thompson, Callum; Marugan-Hernandez, Virginia; Dessens, Johannes T
May 2024
Large-scale statistical analysis of Mycobacterium tuberculosis genome sequences identifies compensatory mutations associated with multi-drug resistance. (2024)
Billows, Nina; Phelan, Jody; Xia, Dong; Peng, Yonghong; Clark, Taane G; Chang, Yu-Mei
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A panel of phenotypically and genotypically diverse bioluminescent:fluorescent Trypanosoma cruzi strains as a resource for Chagas disease research. (2024)
Olmo, Francisco; Jayawardhana, Shiromani; Khan, Archie A; Langston, Harry C; Francisco, Amanda Fortes; Atherton, Richard L; Ward, Alex I; Taylor, Martin C; Kelly, John M; Lewis, Michael D
Genomic diversity and antimicrobial resistance in clinical Klebsiella pneumoniae isolates from tertiary hospitals in Southern Ghana. (2024)
Mills, Richael O; Dadzie, Isaac; Le-Viet, Thanh; Baker, David J; Addy, Humphrey PK; Akwetey, Samuel A; Donkoh, Irene E; Quansah, Elvis; Semanshia, Prince S; Morgan, Jennifer; Mensah, Abraham; Adade, Nana E; Ampah, Emmanuel O; Owusu, Emmanuel; Mwintige, Philimon; Amoako, Eric O; Spadar, Anton; Holt, Kathryn E; Foster-Nyarko, Ebenezer
Using 16s rRNA sequencing to characterize the microbiome of tropical cutaneous ulcer disease: insights into the microbial landscape and implications for diagnosis and treatment. (2024)
Handley, Becca L; Sokana, Oliver; Addo, Kennedy Kwasi; Wagner, Josef; Fookes, María; Harding-Esch, Emma; Marks, Michael; Thomson, Nicholas R; Doyle, Ronan M
Study of the Determinants of Enteric Neuropathy in Experimental Chagas Disease. (2024)
Langston, H
Synthesis and Anti-Chagas Activity Profile of a Redox-Active Lead 3-Benzylmenadione Revealed by High-Content Imaging. (2024)
Trometer, Nathan; Pecourneau, Jérémy; Feng, Liwen; Navarro-Huerta, José A; Lazarin-Bidóia, Danielle; de Oliveira Silva Lautenschlager, Sueli; Maes, Louis; Fortes Francisco, Amanda; Kelly, John M; Meunier, Brigitte; Cal, Monica; Mäser, Pascal; Kaiser, Marcel; Davioud-Charvet, Elisabeth
Enteric nervous system regeneration and functional cure of experimental digestive Chagas disease with trypanocidal chemotherapy. (2024)
Khan, Archie A; Langston, Harry C; Walsh, Louis; Roscoe, Rebecca; Jayawardhana, Shiromani; Francisco, Amanda Fortes; Taylor, Martin C; McCann, Conor J; Kelly, John M; Lewis, Michael D
Measuring protective efficacy and quantifying the impact of drug resistance: A novel malaria chemoprevention trial design and methodology. (2024)
Mousa, Andria; Cuomo-Dannenburg, Gina; Thompson, Hayley A; Chico, R Matthew; Beshir, Khalid B; Sutherland, Colin J; Schellenberg, David; Gosling, Roly; Alifrangis, Michael; Hocke, Emma Filtenborg; Hansson, Helle; Chopo-Pizarro, Ana; Mbacham, Wilfred F; Ali, Innocent M; Chaponda, Mike; Roper, Cally; Okell, Lucy C
Identification of 2 Novel Subtypes of Hepatitis C Virus Genotype 8 and a Potential New Genotype Successfully Treated With Direct Acting Antivirals. (2024)
Mbisa, Jean L; Lapp, Zena; Bibby, David F; Phillips, Laura T; Manso, Carmen F; Packer, Simon; Simmons, Ruth; Harris, Kathryn; Mohan, Jaiganesh; Chinnappan, Lalitha; Leitner, Thomas; Bradshaw, Daniel
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Evaluation of the precision of the Plasmodium knowlesi growth inhibition assay for Plasmodium vivax Duffy-binding protein-based malaria vaccine development. (2024)
Mertens, Jonas E; Rigby, Cassandra A; Bardelli, Martino; Quinkert, Doris; Hou, Mimi M; Diouf, Ababacar; Silk, Sarah E; Chitnis, Chetan E; Minassian, Angela M; Moon, Robert W; Long, Carole A; Draper, Simon J; Miura, Kazutoyo
A novel regulatory interplay between atypical B12 riboswitches and uORF translation in Mycobacterium tuberculosis. (2024)
Kipkorir, Terry; Polgar, Peter; Barker, Declan; D'Halluin, Alexandre; Patel, Zaynah; Arnvig, Kristine B
April 2024
The impact of within-host coinfection interactions on between-host parasite transmission dynamics varies with spatial scale. (2024)
Keegan, Shaun P; Pedersen, Amy B; Fenton, Andy
Investigating the generation and maintenance of immunological memory to malaria infection. (2024)
Macalinao, ML
Visceral leishmaniasis in the hills of western Nepal: A transmission assessment. (2024)
Uranw, Surendra; Bhattarai, Narayan Raj; Cloots, Kristien; Roy, Lalita; Rai, Keshav; Kiran, Usha; Pyakurel, Uttam Raj; Lal, Bibek Kumar; Burza, Sakib; Rijal, Suman; Karki, Prahlad; Khanal, Basudha; Hasker, Epco
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Altered TFEB subcellular localization in nigral neurons of subjects with incidental, sporadic and GBA-related Lewy body diseases. (2024)
Moors, Tim E; Morella, Martino L; Bertran-Cobo, Cesc; Geut, Hanneke; Udayar, Vinod; Timmermans-Huisman, Evelien; Ingrassia, Angela MT; Brevé, John JP; Bol, John GJM; Bonifati, Vincenzo; Jagasia, Ravi; van de Berg, Wilma DJ
A genomic investigation into three malaria vectors: An. darlingi, An. funestus, and An. stephensi. (2024)
Acford-Palmer, H
Immunogenicity and Vaccine Shedding After 1 or 2 Doses of rVSVΔG-ZEBOV-GP Ebola Vaccine (ERVEBO®): Results From a Phase 2, Randomized, Placebo-controlled Trial in Children and Adults. (2024)
Lee, Andrew W; Liu, Ken; Lhomme, Edouard; Blie, Julie; McCullough, John; Onorato, Matthew T; Connor, Laurie; Simon, Jakub K; Dubey, Sheri; VanRheenen, Susan; Deutsch, Jonathan; Owens, Abigail; Morgan, Amy; Welebob, Carolee; Hyatt, Donna; Nair, Sunita; Hamzé, Benjamin; Guindo, Oumar; Sow, Samba O; Beavogui, Abdoul H; Leigh, Bailah; Samai, Mohamed; Akoo, Pauline; Serry-Bangura, Alimamy; Fleck, Suzanne; Secka, Fatou; Lowe, Brett; Watson-Jones, Deborah; Roy, Céline; Hensley, Lisa E; Kieh, Mark; Coller, Beth-Ann G; PREVAC Study Team
RNA genome packaging and capsid assembly of bluetongue virus visualized in host cells. (2024)
Xia, Xian; Sung, Po-Yu; Martynowycz, Michael W; Gonen, Tamir; Roy, Polly; Zhou, Z Hong
March 2024
Multi-Gene Recombinant Baculovirus Expression Systems: From Inception to Contemporary Applications. (2024)
Bissett, Sara L; Roy, Polly
Understanding and maximising the community impact of seasonal malaria chemoprevention in Burkina Faso (INDIE-SMC): study protocol for a cluster randomised evaluation trial. (2024)
Moreno, Marta; Barry, Aissata; Gmeiner, Markus; Yaro, Jean Baptist; Sermé, Samuel S; Byrne, Isabel; Ramjith, Jordache; Ouedraogo, Alphonse; Soulama, Issiaka; Grignard, Lynn; Soremekun, Seyi; Koele, Simon; Ter Heine, Rob; Ouedraogo, Amidou Z; Sawadogo, Jean; Sanogo, Edith; Ouedraogo, Issa N; Hien, Denise; Sirima, Sodiomon Bienvenu; Bradley, John; Bousema, Teun; Drakeley, Chris; Tiono, Alfred B
February 2024
Unpacking the “complex” in complex evaluations: lessons learned conducting large scale evaluations of maternal and child health programmes over 20 years of collaborative research in Ghana. (2024)
Soremekun, Seyi; Amenga-Etego, Seeba; Kirkwood, Betty
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Characterization of merozoite-specific thrombospondin-related anonymous protein (MTRAP) in Plasmodium vivax and P. knowlesi parasites. (2024)
Sy Thau, Nguyen; Nguyen, Tuyet-Kha; Truong, Nguyen Van; Chu, Thi-Thanh Hang; Na, Sung-Hun; Moon, Robert W; Lau, Yee Ling; Nyunt, Myat Htut; Park, Won-Sun; Chun, Wan-Joo; Lu, Feng; Lee, Seong-Kyun; Han, Jin-Hee; Han, Eun-Taek
Phenotypic and genotypic characterization of Campylobacter coli isolates from the Vietnamese poultry production network; a pilot study. (2024)
Lehri, Burhan; Navoly, Georgina; Corser, Abigail; Nasher, Fauzy; Willcocks, Sam; Pham, Thi Ngoc; Wren, Brendan W; Luu, Quynh Huong; Stabler, Richard A
A validated pangenome-scale metabolic model for the Klebsiella pneumoniae species complex. (2024)
Cooper, Helena B; Vezina, Ben; Hawkey, Jane; Passet, Virginie; López-Fernández, Sebastián; Monk, Jonathan M; Brisse, Sylvain; Holt, Kathryn E; Wyres, Kelly L
Risk factors for non-participation in ivermectin and dihydroartemisinin-piperaquine mass drug administration for malaria control in the MASSIV trial. (2024)
Kositz, Christian; Vasileva, Hristina; Mohammed, Nuredin; Achan, Jane; Dabira, Edgard Diniba; D'Alessandro, Umberto; Bradley, John; Marks, Michael
Antibiotic susceptibility patterns of pathogens isolated from hospitalized patients with advanced HIV disease (AHD) in Bihar, India. (2024)
Kumar, Vikash; Murali, Shreyas; Goldberg, Jacob; Alonso, Beatriz; Moretó-Planas, Laura; Reid, Anthony; Harshana, Amit; Burza, Sakib; Mahajan, Raman
January 2024
Investigating New Roles for Septins in Host-Pathogen Interactions Using Staphylococcus aureus. (2024)
Robertin, S
Shining a Light on Dense Granules – A Biochemical,
Genetic and Cell Biological Investigation of an Essential
but Understudied Compartment of the Malaria Parasite. (2024)
Vallintine, TMR
Is Brazil reaching malaria elimination? A time series analysis of malaria cases from 2011 to 2023. (2024)
Garcia, Klauss Kleydmann Sabino; Soremekun, Seyi; Abrahão, Amanda Amaral; Marchesini, Paola Barbosa; Drakeley, Chris; Ramalho, Walter Massa; Siqueira, André M
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A platform for genome editing insect vectors of leishmaniasis
(Lutzomyia longipalpis and Phlebotomus papatasi) and Chagas disease (Rhodnius prolixus) via CRISPR-Cas9 based approaches. (2024)
Brandner-Garrod, LJ
Naturally acquired adaptive immunity to Streptococcus pneumoniae is impaired in rheumatoid arthritis patients. (2024)
Ercoli, Giuseppe; Selway-Clarke, Hugh; Truijen, Dena; Folkmanaite, Milda; Oulton, Tate; Norris-Grey, Caitlin; Nakajima, Rie; Felgner, Philip; Wren, Brendan W; Tetteh, Kevin; Croucher, Nicholas J; Leandro, Maria; Cambridge, Geraldine; Brown, Jeremy S
Asymptomatic Plasmodium falciparum carriage at the end of the dry season is associated with subsequent infection and clinical malaria in Eastern Gambia. (2024)
Fogang, Balotin; Lellouche, Lionel; Ceesay, Sukai; Drammeh, Sainabou; Jaiteh, Fatou K; Guery, Marc-Antoine; Landier, Jordi; Haanappel, Cynthia P; Froberg, Janeri; Conway, David; D'Alessandro, Umberto; Bousema, Teun; Claessens, Antoine
Changes in serum concentration of perioperative inflammatory cytokines following the timing of surgery among mild-moderate traumatic brain injury patients and factors associated. (2024)
Lekuya, Hervé Monka; Cose, Stephen; Nakibuule, Marjorie; Ahimbisibwe, Gift; Fuller, Anthony; Kamabu, Larrey Kasereka; Biryabarema, Emmanuel; Olweny, Geoffrey; Kateete, David Patrick; Kirabira, Anthony; Makumbi, Fredrick; Vandersteene, Jelle; Baert, Edward; Galukande, Moses; Kalala, Jean-Pierre Okito
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Optimisation-based modelling for explainable lead discovery in malaria. (2024)
Li, Yutong; Cardoso-Silva, Jonathan; Kelly, John M; Delves, Michael J; Furnham, Nicholas; Papageorgiou, Lazaros G; Tsoka, Sophia
Acute and long-term outcomes of SARS-CoV-2 infection in school-aged children in England: Study protocol for the joint analysis of the COVID-19 schools infection survey (SIS) and the COVID-19 mapping and mitigation in schools (CoMMinS) study. (2024)
Looker, Katharine J; McClenaghan, Elliot; Judd, Alison; Pierotti, Livia; Downing, Harriet; Phelan, Jody; Warren-Gash, Charlotte; Ngozi, Kalu; Dawe, Fiona; Relton, Caroline; Christensen, Hannah; Hay, Alastair D; Mangtani, Punam; Nguipdop-Djomo, Patrick; Denholm, Rachel
Induced Burkholderia prophages detected from the hemoculture: a biomarker for Burkholderia pseudomallei infection. (2024)
Withatanung, Patoo; Janesomboon, Sujintana; Vanaporn, Muthita; Muangsombut, Veerachat; Charoensudjai, Sorujsiri; Baker, Dave J; Wuthiekanun, Vanaporn; Galyov, Edouard E; Clokie, Martha RJ; Gundogdu, Ozan; Korbsrisate, Sunee
2024
Household-level effects of seasonal malaria chemoprevention in the Gambia. (2024)
Soremekun, Seyi; Conteh, Bakary; Nyassi, Abdoullah; Soumare, Harouna M; Etoketim, Blessed; Ndiath, Mamadou Ousmane; Bradley, John; D'Alessandro, Umberto; Bousema, Teun; Erhart, Annette; Moreno, Marta; Drakeley, Chris