Items where Faculty or Department is "Dept of Medical Statistics"

LSHTM Organisational Structure (63219)

Faculty of Epidemiology and Population Health (28272)

Dept of Medical Statistics (4648) Month Authors/Creators Item Type Full Text

Article

SARS-CoV-2-specific humoral immunity in a Norwegian cohort between 2020 and 2023. (2025) Sarjomaa, Marjut; Berg, Kristine Karlsrud; Jaioun, Keson; Tveten, Yngvar; Kersten, Hege; Reiso, Harald; Eikeland, Randi; Thilesen, Carina; Nordbø, Svein Arne; Aaberge, Ingeborg S; Pearce, Neil; Fell, Anne Kristin Moeller

Development and validation of a diagnostic prediction model for pancreatic ductal adenocarcinoma: VAPOR 1, protocol for a prospective multicentre case-control study. (2025) Walsh, Caoimhe M; Murray, James; Laponogov, Ivan; Parker, Aaron; Ellis, James K; Converso, Valerio; Austin, Emma; Boshier, Piers R; Czajkowski, Charles; Spalding, Duncan; Al-Mukhtar, Ahmed; Frampton, Adam E; Roberts, Keith J; Pandanaboyana, Sanjay; Halloran, Chris; Costello, Eithne; Kocher, Hemant; Mitra, Vikramjit; Hamady, Zaed; Al-Sarireh, Bilal; Pathak, Samir; Mitchell, William Kyle; Siriwardena, Ajith Kumar; Westlake, Claire; Pereira, Stephen P; Spiliotis, Ioannis; Biswas, Sujata; Vapor Collaborators; Španěl, Patrik; Veselkov, Kirill; Sharples, Linda D; Hanna, George B; VAPOR Collaborators

Accelerated long-term forgetting as a predictor of clinical onset in presymptomatic autosomal dominant Alzheimer’s disease. (2025) Magill, Nicholas; Tank, Rachana; Ferguson, Damien; Alston, Duncan; O’Connor, Antoinette; Rice, Helen; Lu, Kirsty; Crutch, Sebastian; Fox, Nick C; Weston, Philip SJ

Surgical Risk and Long-Term Mortality With PCI and CABG in Ischemic Left Ventricular Systolic Dysfunction. (2025) Marquis-Gravel, Guillaume; Tong, Guangyu; Dodd, Matthew; Clayton, Tim; Ryan, Matthew; Docherty, Kieran F; Williams, Alicia; Sun, Jiaxuan; Fremes, Stephen E; Lansky, Alexandra; Velazquez, Eric J; Perera, Divaka; Petrie, Mark C; Rouleau, Jean-Lucien

Therapeutics Dataset from COVID-19 Medicine Delivery Units in England: an OpenSAFELY Data Report [version 2; peer review: 2 approved with reservations]. (2025) Nab, Linda; Green, Amelia; Higgins, Rose; Zheng, Bang; Schultze, Anna; Tazare, John; Mahalingasivam, Viyaasan; Inglesby, Peter; Davy, Simon; Smith, Rebecca; Mehrkar, Amir; Bates, Christopher; Cockburn, Jonathan; Marks, Michael; Brown, Michael; Wiedemann, Milan; Walker, Alex; Douglas, Ian; Goldacre, Ben; MacKenna, Brian; Tomlinson, Laurie; Curtis, Helen

Comparison of outcomes after living and deceased donor kidney transplantation: UK national cohort study. (2025) Murray, James; Luke, Annabel; Wallace, David; Callaghan, Chris; Sharples, Linda D

Quantitative bias analysis for mismeasured variables in health research: a review of software tools. (2025) Wood, Codie JC; Tilling, Kate; Bartlett, Jonathan W; Hughes, Rachael A

Perinatal outcomes of symptomatic chikungunya, dengue and Zika infection during pregnancy in Brazil: a registry-based cohort study. (2025) Cerqueira-Silva, Thiago; Rodrigues, Laura C; Pearce, Neil; Teixeira, Maria Gloria; Costa, Maria da Conceição Nascimento; Cardim, Luciana; Boaventura, Viviane S; Lawlor, Deborah A; Barreto, Mauricio L; Paixao, Enny S

Evidence-Based Approaches to Quality Improvement: A Narrative Review of Integrating Bayesian Adaptive Trials Into Health Services. (2025) Kim, Min Jung; Prieto-Merino, David; Nicholas, Jennifer; Allen, Luke; Burton, Matthew J; Bastawrous, Andrew; Macleod, David

Associations of prior wasting malnutrition with later indicators of glucose tolerance across 4 cohorts in Africa and Asia: The Severe Acute Malnutrition - the Role of the Pancreas (SAMPA) study. (2025) Modoc, Dixi Paglinawan; Ahmed, Sana; Chisenga, Molly; Cox, Sharon E; Dasgupta, Riddhi; Duazo, Paulita; Faurholt-Jepsen, Daniel; Kasonka, Lackson; Kelly, Paul; Keogh, Ruth; Kweka, Belinda; Krogh-Madsen, Rikke; Lee, Nanette; Malindisa, Evangelista; Nitsch, Dorothea; Ngoya, Patrick; PrayGod, George; Shaw, James Am; Solon, Juan Antonio; Tembo, Mizinga Jacqueline; Trilok-Kumar, Geeta; Filteau, Suzanne picture_as_pdf

Agreement between parent reported and clinical coding of asthma, eczema and allergic rhinitis: The multi-ethnic Born in Bradford cohort. (2025) Santorelli, Gillian; Pembrey, Lucy; Wright, John

A Bayesian life-course linear structural equations model (BLSEM) to explore the development of body mass index (BMI) from the prenatal stage until middle age. (2025) Tzala, Evangelia; Banterle, Marco; Karhunen, Ville; Bond, Tom A; Tolvanen, Mimmi; Kaakinen, Marika; Sebert, Sylvain; Lewin, Alex; Jarvelin, Marjo-Riitta

Rationale and design of SCOPE trial: a prospective, multicentre, open-label, randomised controlled trial to evaluate the overall efficacy and safety of a short-term anticoagulation strategy versus conventional single antiplatelet therapy in patients with severe aortic stenosis without indications for anticoagulation or dual antiplatelet therapy post-transcatheter aortic valve replacement. (2025) Yan, Yunfeng; Li, Yang; Liu, Ran; Zhang, Lihua; Liu, Xinmin; Yuan, Fei; Jiang, Zhengming; Luo, Taiyang; Lu, Zhinan; Wang, Yang; Zhu, Yingxuan; Tang, Yi-Da; Zhang, Huiping; Wu, Wei; Li, Yan; Guo, Liang; Pocock, Stuart; Song, Guangyuan; Investigators, Scope

Non-invasive breath testing to detect colorectal cancer: protocol for a multicentre, case-control development and validation study (COBRA2 study). (2025) Fadel, Michael G; Murray, James; Woodfield, Georgia; Belluomo, Ilaria; Laponogov, Ivan; Parker, Aaron; Converso, Valerio; Ellis, James K; Wheatstone, Pete; Hepburn, Julie; Groves, Chris; Monahan, Kevin; Saunders, Brian P; Španěl, Patrik; Veselkov, Kirill; Cross, Amanda J; Kontovounisios, Christos; Sharples, Linda D; Hanna, George B; COBRA2 Collaborators

The Risks of Risk Assessment: Causal Blind Spots When Using Prediction Models for Treatment Decisions. (2025) van Geloven, Nan; Keogh, Ruth H; van Amsterdam, Wouter; Cinà, Giovanni; Krijthe, Jesse H; Peek, Niels; Luijken, Kim; Magliacane, Sara; Morzywołek, Paweł; van Ommen, Thijs; Putter, Hein; Sperrin, Matthew; Wang, Junfeng; Weir, Daniala L; Didelez, Vanessa

The Estimand Framework and Causal Inference: Complementary Not Competing Paradigms. (2025) Drury, Thomas; Bartlett, Jonathan W; Wright, David; Keene, Oliver N

Impact of distribution of facemasks on community incidence and outcomes of COVID-19: A cluster randomised trial in India. (2025) Mallinson, Poppy AC; Dasi, Teena; Banjara, Santosh Kumar; Lieber, Judith; Bhogadi, Santhi; Addanki, Srivalli; Undrajavarapu, Prasad; Masapeta, Subhash; Mahajan, Hemant; Kulkarni, Bharati; Kinra, Sanjay

Development of START-EDI guidelines for reporting equality, diversity and inclusion in research: a study protocol. (2025) Fadel, Michael G; Kettley-Linsell, Hannah; Boshier, Piers R; Barnes, Rebecca; Newby, Christopher; Manyara, Anthony Muchai; Buckle, Peter; Vyas, Darshali A; Hepburn, Julie; Edgar-Jones, Philip; Rai, Tanvi; Nicholson, Brian D; Cross, Amanda J; Sharples, Linda D; Hopewell, Sally; Cohen, Jérémie F; Welch, Vivian; Bossuyt, Patrick Mm; Hanna, George B

Co-creating inclusive sexual health services for middle-aged and older adults, including disabled people, in England: an innovative participatory approach within the field of sexual health. (2025) Conyers, Hayley; Sakuma, Yoshiko; Jannaway, Tracey; Cowan, Alex; Tucker, Joseph D; Kpokiri, Eneyi E; Wu, Dan

Efficient statistical analysis of trial designs: win ratio and related approaches for composite outcomes. (2025) Fandino, Wilson; Dodd, Matthew; Kunst, Gudrun; Clayton, Tim

Associations between night/shift working and late-life brain health. (2025) King-Robson, Josh; Nicholas, Jennifer M; James, Sarah-Naomi; Keshavan, Ashvini; Williams, Dylan M; Groves, James; Sudre, Carole H; Lu, Kirsty; Barnes, Josephine; Coath, William; Cash, David M; Keuss, Sarah E; Richards, Marcus; Warren, Jason D; Schott, Jonathan M

Concurrent validity, test-retest reliability, and normative properties of the ignite app: A cognitive assessment for frontotemporal dementia. (2025) Convery, Rhian S; Adams-Carr, Kerala; Nicholas, Jennifer M; Moore, Katrina M; Goldsmith, Sophie; Bocchetta, Martina; Russell, Lucy L; Rohrer, Jonathan D

Evaluation of a Hub-and-Spoke Model to Enhance Healthcare Professionals' Practice of Antimicrobial Stewardship (AMS) Programmes in the Volta Region of Ghana. (2025) McErlean, Mairead; Kpokiri, Eneyi; Panesar, Preet; Cooper, Emily E; Jato, Jonathan; Orman, Emmanuel; Odoi, Hayford; Hutton-Nyameaye, Araba; Somuah, Samuel O; Folitse, Isaac; Aku, Thelma A; Ben, Inemesit O; Farragher, Melissa; Hail, Leila; Dodoo, Cornelius C; Jani, Yogini H

Sustained natural immunity following SARS-CoV-2 infection against severe COVID-19 outcomes and symptomatic reinfection: analyses of national data for Brazil and Scotland. (2025) Haider, Fasih; Cerqueira-Silva, Thiago; Hainey, Kirsten J; Millington, Tristan; Shah, Syed Ahmar; de Araujo Oliveira, Vincius; Pearce, Neil; Barreto, Mauricio L; Boaventura, Viviane Sampaio; Katikireddi, Srinivasa Vittal; Robertson, Chris; Barral-Netto, Manoel; Sheikh, Aziz

Long-Term Safety and Efficacy of Renal Denervation: 24-Month Results From the SPYRAL HTN-ON MED Trial. (2025) Kandzari, David E; Mahfoud, Felix; Townsend, Raymond R; Kario, Kazuomi; Weber, Michael A; Schmieder, Roland E; Tsioufis, Konstantinos; Pocock, Stuart; Liu, Minglei; DeBruin, Vanessa; Brar, Sandeep; Böhm, Michael

Association between objectively assessed physical activity and kidney function among female agricultural workers in hot environments in Spain. (2025) Koch, Sarah; Buekers, Joren; Espinosa, Ana; Gómez-Salgado, Juan; Pombo, Gabriel; Werkman, Loes; Arjona, Lourdes; Al Rashed, Ali; Caplin, Ben; Kogevinas, Manolis; Brocal-Fernandez, Francisco; Oomatia, Amin; Pearce, Neil; Ramirez-Rubio, Oriana; Ruíz-Frutos, Carlos; Garcia-Aymerich, Judith; O'Callaghan-Gordo, Cristina picture_as_pdf

Catheter and Surgical Ablation for Atrial Fibrillation : A Systematic Review and Meta-analysis. (2025) Montané, Bryce; Zhang, Shiyang; Wolfe, Jonathan D; Prime, Sabrina; Luo, Chongliang; Cooper, Daniel H; Doering, Michelle; Blomstrom-Lundqvist, Carina; Nashef, Samer AM; Osmancik, Pavel; Andrade, Jason G; Bertaglia, Emanuele; Parkash, Ratika; Mark, Daniel B; Nielsen, Jens C; Sharples, Linda D; Gage, Brian F

Causal machine learning for heterogeneous treatment effects in the presence of missing outcome data. (2025) Pryce, Matthew; Diaz-Ordaz, Karla; Keogh, Ruth H; Vansteelandt, Stijn

Executive Dysfunction and Disability in SPMS: Predictive Value of the Frontal Assessment Battery in the UCLH MS-STAT2 Cohort. (2025) Wade, Charles; Doshi, Anisha; Mangion, Sean Apap; Williams, Tom; Bianchi, Alessia; De Angelis, Floriana; Wright, Sarah; John, Nevin; Calvi, Alberto; Braisher, Marie; Blackstone, James; Nicholas, Jennifer; Chataway, Jeremy; UCL MS‐STAT2 Investigators

Cost-effectiveness of the CV-polypill strategy versus standard care for secondary cardiovascular prevention in Spain: an analysis based on the SECURE trial. (2025) Gaziano, Thomas; Castellano, José María; Dymond, Amy; Looby, Alissa; Mealing, Stuart; Owen, Ruth; Pocock, Stuart; González-Juanatey, José Ramón; Cordero, Alberto; Fernández-Ortiz, Antonio; Linhart, Aleš; Schiele, François; Doehner, Wolfram; Fernández, Luisa Ojeda; Fuster, Valentín

Occupational health in the era of climate change and the green transition: a call for research. (2025) Turner, Michelle C; Basagaña, Xavier; Albin, Maria; Broberg, Karin; Burdorf, Alex; van Daalen, Kim R; Guseva Canu, Irina; Kolstad, Henrik A; Kogevinas, Manolis; Lowe, Rachel; Pearce, Neil; Pega, Frank; Saget, Catherine; Schubauer-Berigan, Mary K; Svensson, Sara; Vineis, Paolo; Straif, Kurt

Long-term kidney outcomes after COVID-19: a matched cohort study using the OpenSAFELY platform. (2025) Mahalingasivam, Viyaasan; Zheng, Bang; Wing, Kevin; Parker, Edward PK; Bhaskaran, Krishnan; Carrero, Juan Jesús; Jayacodi, Sandra; Jumbo, Edith; Miah, Tamanna; Gracey, Brian; Tazare, John; Santhakumaran, Shalini; Mathur, Rohini; Costello, Ruth E; Herrett, Emily; Wen, Qing; Hartney, Thomas; Douglas, Ian J; Green, Amelia; Fisher, Louis; Curtis, Helen J; Walker, Alex J; MacKenna, Brian; Hulme, William J; Mehrkar, Amir; Bacon, Sebastian; Goldacre, Ben; Williamson, Elizabeth; Nitsch, Dorothea; Mansfield, Kathryn E; Tomlinson, Laurie

Feasibility study of Learning Together for Mental Health: fidelity, reach and acceptability of a whole-school intervention aiming to promote health and wellbeing in secondary schools. (2025) Sundaram, Neisha; Lloyd-Houldey, Oliver; Sturgess, Joanna; Allen, Elizabeth; Michalopoulou, Semina; Hope, Steven; Legood, Rosa; Scott, Stephen; Hudson, Lee D; Nicholls, Dasha; Christie, Deborah; Viner, Russell M; Bonell, Chris

Unintended consequences of a financial incentive scheme for fruit and vegetable purchasing in an unorganised retail setting in rural India. (2025) Lieber, Judith; Kinra, Sanjay; Addanki, Srivalli; Prabhakar, Swarnaa; Bhogadi, Santhi; Mallinson, Poppy AC; Kurpad, Anura V; Walls, Helen L; Kulkarni, Bharati; Aggarwal, Shilpa; Pande, Richa; Selvaraj, Kiruthika; Debbarma, Arindam; Deo, Sarang; Kannuri, Nanda Kishore

Re-Evaluating Recurrent Events in Heart Failure Trials: Patterns, Prognostic Implications, and Analytical Improvements. (2025) Hazewinkel, Audinga-Dea; Gregson, John; Pocock, Stuart J; McMurray, John; Solomon, Scott D; Claggett, Brian; Packer, Milton; Anker, Stefan D; Ferreira, João P; Docherty, Kieran; Henderson, Alasdair; Jhund, Pardeep; Wilderäng, Ulrica; Wright, David picture_as_pdf

Causes and MEchanisms foR non-atopic Asthma in Children (CAMERA) study: rationale and protocol. (2025) Njoroge, Mary; Pinheiro, Gabriela Pimentel; Santana, Cinthia Vila Nova; Ali, Hajar; Hobbs, Stephanie; Mena-Bucheli, Santiago; Romero-Sandoval, Natalia; Robertson, Steven; Rutter, Charlotte E; Davoren, Donna; Brooks, Collin; Douwes, Jeroen; Cooper, Philip J; Mpairwe, Harriet; Figueiredo, Camila A; Cruz, Alvaro A; Barreto, Mauricio L; Pearce, Neil; Pembrey, Lucy; CAMERA study group

Associations between cancer survivorship and subsequent respiratory disease: a systematic literature review. (2025) Andresen, Kirsty; Carreira, Helena; Jain, Ruchika; Forbes, Harriet; Williamson, Elizabeth; Quint, Jennifer K; Bhaskaran, Krishnan

Multiple Imputation of Missing Covariates When Using the Fine-Gray Model. (2025) Bonneville, Edouard F; Beyersmann, Jan; Keogh, Ruth H; Bartlett, Jonathan W; Morris, Tim P; Polverelli, Nicola; de Wreede, Liesbeth C; Putter, Hein

Efficacy of digital cognitive behavioral therapy for treating insomnia in adults aged 65 and older: a secondary analysis using individual participant data from three randomized controlled trials. (2025) Tarnai, Kathryn A; Miller, Christopher B; Magill, Nicholas; Emsley, Richard; Robinson, Will; Kyle, Simon D; McGrath, Emer R; Espie, Colin A; Henry, Alasdair L picture_as_pdf

Exploring geographic differences in IgE response through network and manifold analyses. (2025) Cucco, Alex; Pearce, Neil; Simpson, Angela; Pembrey, Lucy; Mpairwe, Harriet; Figueiredo, Camila A; Cooper, Philip J; Douwes, Jeroen; Brooks, Collin; Adcock, Ian M; Kermani, Nazanin Zounemat; Roberts, Graham DM; Murray, Clare S; Custovic, Adnan; Fontanella, Sara; WASP Study Group; STELAR/UNICORN Consortium; U-BIOPRED Consortium picture_as_pdf

Evaluating impacts of improved flooring on enteric and parasitic infections in rural households in Kenya: study protocol for a cluster-randomised controlled trial. (2025) Halliday, Katherine E; Kepha, Stella; Legge, Hugo; Allen, Elizabeth; Dreibelbis, Robert; Elson, Lynne; Kakoi, Beatrice K; Mcharo, Carlos; Muli, Sharon; Mwongeli, Jacinta; Njomo, Doris; Njoroge, Margaret M; Ochwal, Victoria; Oswald, William E; Rono, Martin; Safari, Tuva K; Filinger, Ulrike; Kaluli, James Wambua; Mwandawiro, Charles S; Pullan, Rachel L

Learning together for mental health: feasibility of measures to assess a whole-school mental health and wellbeing intervention in secondary schools. (2025) Lloyd-Houldey, Oliver; Sturgess, Joanna; Sundaram, Neisha; Hope, Steven; Michalopoulou, Semina; Allen, Elizabeth; Hudson, Lee; Scott, Stephen; Nicholls, Dasha; Christie, Deborah; Legood, Rosa; Bonell, Chris; Viner, Russell

Ultra-fast MRI for dementia diagnosis and treatment eligibility: A prospective study. (2025) Rosa-Grilo, Miguel; Chughtai, Haroon R; Thomas, David L; Alexander, Daniel C; Beament, Millie; Belder, Christopher RS; Jäger, H Rolf; Lim, Emma A; Magill, Nicholas; Mallon, Dermot; Nicholas, Jennifer M; Nicholas, Owen; Urban, Floey; Parker, Geoff JM; Barkhof, Frederik; Mummery, Catherine J; Fox, Nick C

Risk factors for atopic and non-atopic asthma in school-aged children from high, and low and middle income countries. (2025) Rutter, Charlotte picture_as_pdf

Can nutrition-sensitive agriculture interventions address intersectional inequalities in women's diets? A mediation analysis using cross-sectional trial data from Odisha, India. (2025) Fivian, Emily; Harris-Fry, Helen; Shankar, Bhavani; Pradhan, Ronali; Mohanty, Satyanarayan; Padhan, Shibanath; Prost, Audrey; Parida, Manoj; Mishra, Naba K; Rath, Shibanand; Rath, Suchitra; Allen, Elizabeth; Kadiyala, Suneetha

Factors associated with symptom-to-surgery time in patients undergoing surgical repair for acute type A aortic dissection: an exploratory analysis from a prospective cohort study. (2025) Fandino, Wilson; Gilbey, Tom; Milne, Benjamin; Arrowsmith, Joe; Agarwal, Seema; Dodd, Matthew; Clayton, Tim C; Kunst, Gudrun; ACTACC Link-person Network

Characteristics of interventions aimed at reducing inequalities along the cancer continuum: A scoping review. (2025) Safari, Wende C; Gravenhorst, Katja; Leyrat, Clemence; Shimizu, Koki; Smith, Matthew J; Aggarwal, Ajay; Maringe, Camille picture_as_pdf

Community engagement and chronic viral hepatitis public health interventions: a systematic review, meta-analysis, and complementary crowdsourcing open call. (2025) Li, Yifan; Kpokiri, Eneyi; Elasi, Dalia; Sheng, Rongrong; Wang, Keying; Conyers, Hayley; Zhang, Ye; Adda, Danjuma K; Matthews, Philippa C; Fitzpatrick, Thomas; Tucker, Joseph D; Wu, Dan picture_as_pdf

Modelling Population Genetic Screening in Rare Neurodegenerative Diseases. (2025) Spargo, Thomas P; Iacoangeli, Alfredo; Ryten, Mina; Forzano, Francesca; Pearce, Neil; Al-Chalabi, Ammar

Optimised medical therapy alone versus optimised medical therapy plus revascularisation for asymptomatic or low-to-intermediate risk symptomatic carotid stenosis (ECST-2): 2-year interim results of a multicentre randomised trial. (2025) Donners, Simone JA; van Velzen, Twan J; Cheng, Suk Fun; Gregson, John; Hazewinkel, Audinga-Dea; Pizzini, Francesca B; Emmer, Bart J; Simister, Robert; Richards, Toby; Lyrer, Philippe A; Maurer, Marina; Smith, Gemma; Tervit, Gareth; van der Steen, Laurine; Pickett, Gwynedd E; Gubitz, Gordon; Roozenbeek, Bob; Scheele, Maaike; Bamford, John M; Kooi, M Eline; de Borst, Gert J; Jäger, Hans Rolf; Brown, Martin M; Nederkoorn, Paul J; Bonati, Leo H; ECST-2 investigators picture_as_pdf

Reply to the commentary of Burkhard Madea and Elke Doberentz on our article "An assessment of the Henssge method for forensic death time estimation in the early post-mortem interval". (2025) Heinrich, Fabian; Ondruschka, Benjamin; Anders-Lohner, Sven

Malnutrition in infants aged under 6 months: prevalence and anthropometric assessment - analysis of 56 low- and middle-income country DHS datasets. (2025) Kerac, Marko; James, Philip T; McGrath, Marie; Brennan, Eilise; Cole, Tim; Opondo, Charles; Frison, Séverine

Letter: Robins-E risk of bias tool. (2025) Steenland, K; Straif, K; Schubauer-Berigan, MK; Demers, PA; Forastiere, F; Stenzel, T; Vermeulen, R; Arroyave, W; Zahm, SH; Pearce, N

Barriers and facilitators to accessing sexual health services among middle-aged and older adults in the UK, including those with disabilities: a qualitative analysis. (2025) Letley, Charlotte; Kritzer, Isabella; Sakuma, Yoshiko; Conyers, Hayley; Randazzo, Sophia; Ong, Jason J; Day, Suzanne; Wu, Dan; Terris-Prestholt, Fern; Tucker, Joseph D; Kpokiri, Eneyi E

Associations between postpartum haemorrhage, postnatal mental health and longer term mental illness: a record-linked cohort study. (2025) Latt, Su Mon; Opondo, Charles; Alderdice, Fiona; Kurinczuk, Jennifer J; Rowe, Rachel

Signal Monitoring for Adverse Events Following Immunisation with COVID-19 Vaccines During the SARS-CoV-2 Pandemic: An Evaluation of the South African Surveillance System. (2025) Sankar, Chenoa; Evans, Stephen; Meyer, Johanna Catharina; Gunter, Hannah May; Sekiti, Victoria; McCarthy, Kerrigan

Kangaroo mother care among hospitalised neonates: evaluation of the validity of duration measurement methods compared to observation linked to the OMWaNA trial in Uganda. (2025) Tumukunde, Victor S; Sekitoleko, Isaac; Opondo, Charles; Nyirenda, Moffat; Tann, Cally J; Lawn, Joy E; Medvedev, Melissa M

Evaluating the performance of common reference laboratory tests for acute dengue diagnosis: a systematic review and meta-analysis of RT-PCR, NS1 ELISA, and IgM ELISA. (2025) Pillay, Kamla; Keddie, Suzanne H; Fitchett, Elizabeth; Akinde, Cassandra; Bärenbold, Oliver; Bradley, John; Falconer, Jane; Keogh, Ruth H; Lim, Zhia Ning; Nezafat Maldonado, Behrouz; Maynard-Smith, Laura; Sugrue, Ellen; Taylor, Okuda; Hopkins, Heidi; Dubot-Pérès, Audrey

Associations between accelerated forgetting, amyloid deposition and brain atrophy in older adults. (2025) Lu, Kirsty; Baker, John; Nicholas, Jennifer M; Street, Rebecca E; Keuss, Sarah E; Coath, William; James, Sarah-Naomi; Keshavan, Ashvini; Weston, Philip SJ; Murray-Smith, Heidi; Cash, David M; Malone, Ian B; Wong, Andrew; Fox, Nick C; Richards, Marcus; Crutch, Sebastian J; Schott, Jonathan M

Empagliflozin in resistant hypertension and heart failure with preserved ejection fraction: the EMPEROR-Preserved trial. (2025) Böhm, Michael; Butler, Javed; Coats, Andrew; Lauder, Lucas; Mahfoud, Felix; Filippatos, Gerasimos; Ferreira, João Pedro; Pocock, Stuart J; Brueckmann, Martina; Hauske, Sibylle J; Schueler, Elke; Wanner, Christoph; Verma, Subodh; Zannad, Faiez; Packer, Milton; Anker, Stefan D

Hybrid, vaccine-induced and natural immunity against SARS-CoV-2 in traditional food markets in Bolivia (2020-2022): A cross-sectional analysis of a serological survey. (2025) Leyns, Christine; McClenaghan, Elliot; Rodriguez, Patricia; Nguipdop-Djomo, Patrick; Ascarrunz, Carla; Eid Rodriguez, Daniel; Mangtani, Punam; Guitian, Javier

Rationale and Design of the CREATE Trial: A Multicenter, Randomized Comparison of Continuation or Cessation of Single Antithrombotic Therapy at 1 Year After Transcatheter Aortic Valve Replacement. (2025) Liu, Ran; Li, Yang; Zhang, Lihua; Lu, Zhinan; Fu, Zhaolin; Modine, Thomas; Jilahawi, Hasan; Pocock, Stuart; Wu, Yongjian; Song, Guangyuan

Ashwagandha (Withania somnifera (L.) Dunal) for promoting recovery in long covid: protocol for a randomised placebo-controlled clinical trial (APRIL Trial). (2025) Mallinson, Poppy Alice Carson; Joshi, Manisha; Mathpathi, Mahesh; Perkins, Alexander; Clayton, Tim; Shah, Anoop Sv; Mathur, Rohini; Birk, Nick; Dhillon, Arandeep; Lieber, Judith; Beg, Sidra S; Hopkins, Lily; Khan, Archie; Allaham, Shereen; Kam, Vanessa Tw; Sutaria, Shailen; R, Galib; Rajagopala, S; Bhamra, Amarjeet; Pillai, Geetha Krishnan G; Khunti, Kamlesh; Nesari, Tanuja; Kinra, Sanjay

Routine Cerebral Embolic Protection during Transcatheter Aortic-Valve Implantation. (2025) Kharbanda, Rajesh K; Kennedy, James; Jamal, Zahra; Dodd, Matthew; Evans, Richard; Bal, Kiran K; Perkins, Alexander D; Blackman, Daniel J; Hildick-Smith, David; Banning, Adrian P; Baumbach, Andreas; Ludman, Peter; Palmer, Stephen; Stables, Rodney H; Henderson, Robert; Appleby, Clare; Cotton, James; Curzen, Nick; Ozkor, Muhiddin; Byrne, Jonathan; Aggarwal, Rajesh; Das, Rajiv; Doshi, Sagar; Watkins, Stuart; Muir, Douglas F; Anderson, Richard; Chowdhary, Saqib; Varcoe, Richard; Dorman, Stephen; Firoozi, Sam; Chelliah, Raj; Owens, Colum; Redwood, Simon; Prendergast, Bernard; Iqbal, Javaid; Ratib, Karim; Dospinescu, Ciprian; Suresh, Venkatesan; Cruden, Nicholas; Rajathurai, Thirumaran; Malik, Iqbal S; Wiper, Andrew; Costopoulos, Charis; Khurana, Ayush; Banning, Amerjeet; Clayton, Tim; BHF PROTECT-TAVI Investigators

Emulating an existing trial of treatments for prostate cancer using real-world data: challenges and lessons learned. (2025) Chesang, Caroline; Sharples, Linda D; Gray, Christen M; Nossiter, Julie; van der Meulen, Jan; Cowling, Thomas E; Keogh, Ruth H

Sample size estimates for biomarker-based outcome measures in clinical trials in autosomal dominant Alzheimer's disease. (2025) Cash, David M; Morgan, Katy E; O'Connor, Antoinette; Veale, Thomas D; Malone, Ian B; Poole, Teresa; Benzinger, Tammie Ls; Gordon, Brian A; Ibanez, Laura; Li, Yan; Llibre-Guerra, Jorge J; McDade, Eric; Wang, Guoqiao; Chhatwal, Jasmeer P; Day, Gregory S; Huey, Edward; Jucker, Mathias; Levin, Johannes; Niimi, Yoshiki; Noble, James M; Roh, Jee Hoon; Sánchez-Valle, Racquel; Schofield, Peter R; Bateman, Randall J; Frost, Chris; Fox, Nick C; Dominantly Inherited Alzheimer Network (DIAN)

"I have to be strong": A qualitative study of parental bereavement experiences in Uganda following the death of their baby. (2025) Stevenson, Georgia; Namukwaya, Stella; Katongole, Joseph; Tumukunde, Victor; Blencowe, Hannah; Seeley, Janet; Tann, Cally J; Lawn, Joy E; Elbourne, Diana; Medvedev, Melissa M picture_as_pdf

Value of hospital administrative data linked to national cancer registry records to identify metastatic disease at time of primary diagnosis in colorectal cancer patients: a study using national data in England. (2025) Almilaji, Orouba; Sharples, Linda; Aggarwal, Ajay; Cromwell, David; Horgan, Kieran; Braun, Michael; Arnott, Robert; Nossiter, Julie; Kuryba, Angela; Lewin, Alexandra; Rous, Brian; Cowling, Thomas; Meulen, Jan Van Der; Walker, Kate picture_as_pdf

Reproducibility of the Unaided Subjective Assessment of Orbital Computed X-Ray Tomographic Features in Thyroid Eye Disease. (2025) Landray, Isobel; Carpenter, James; Vahdani, Kaveh; Miszkiel, Katherine; Ratnam, Lakshmi A; Rose, Geoffrey E picture_as_pdf

Kangaroo mother care before stabilisation: the OMWaNA trial - Authors' reply. (2025) Medvedev, Melissa M; Tumukunde, Victor; Tann, Cally J; Opondo, Charles; Lawn, Joy E picture_as_pdf

How Do Early Weight Trajectories Explain Social Inequalities in Lung Function in Children With Cystic Fibrosis?: A Longitudinal Interventional Disparity Effects Analysis With Time-varying Mediators and Intermediate Confounders. (2025) Schlüter, Daniela K; Keogh, Ruth H; Daniel, Rhian M; Agbla, Schadrac C; Taylor-Robinson, David picture_as_pdf

Pilot implementation of short message service for randomisation in a multisite pragmatic factorial clinical trial in Kenya. (2025) Chepkirui, Mercy; Kimego, Dennis; Nzioki, Charles; Jowi, Elizabeth; Opondo, Charles; Agweyu, Ambrose picture_as_pdf

Risk, determinants, and persistence of long-COVID in a population-based cohort study in Catalonia. (2025) Kogevinas, Manolis; Karachaliou, Marianna; Espinosa, Ana; Iraola-Guzmán, Susana; Castaño-Vinyals, Gemma; Delgado-Ortiz, Laura; Farré, Xavier; Blay, Natàlia; Pearce, Neil; Bosch de Basea, Magda; Nogués, Eva Alonso; Dobaño, Carlota; Moncunill, Gemma; de Cid, Rafael; Garcia-Aymerich, Judith

Case-Control Study of Congenital Anomalies: Study Methods and Nonresponse Bias Assessment. (2025) Eng, Amanda; Mannetje, Andrea 't; Ellison-Loschmann, Lis; Borman, Barry; Cheng, Soo; Lawlor, Deborah A; Douwes, Jeroen; Pearce, Neil

Effects of azithromycin in young adults with cystic fibrosis: a protocol for emulating a published randomised controlled trial using registry data. (2025) Granger, Emily; Todd, Jonathan; Charman, Susan Christine; Cromwell, Elizabeth; Davies, Gwyneth; Frost, Freddy; Gifford, Alex; Huang, Bin; Hamblett, Nicole Mayer; Naehrlich, Lutz; Ostrenga, Josh; Stanojevic, Sanja; Szczesniak, Rhonda; Keogh, Ruth; CF Trial Emulation Network (CF-TEN)

Pattern Mixture Sensitivity Analyses via Multiple Imputations for Non-Ignorable Dropout in Joint Modeling of Cognition and Risk of Dementia. (2025) Gorbach, Tetiana; Carpenter, James R; Frost, Chris; Josefsson, Maria; Nicholas, Jennifer; Nyberg, Lars picture_as_pdf

Analyzing Coarsened and Missing Data by Imputation Methods. (2025) van der Burg, Lars LJ; Böhringer, Stefan; Bartlett, Jonathan W; Bosse, Tjalling; Horeweg, Nanda; de Wreede, Liesbeth C; Putter, Hein picture_as_pdf

Changes in global quality of life after treatment with immune checkpoint inhibitors in patients receiving different treatment regimens for advanced stage lung cancer in the Netherlands: a 2015-2021 cohort study. (2025) Malhotra, Ananya; Suazo-Zepeda, Erick; Vinke, Petra C; de Bock, Geertruida H; Maas, Willemijn J; Hiltermann, Jeroen TJN; Rachet, Bernard; Leyrat, Clémence; Quaresma, Manuela picture_as_pdf

Falling Asleep on the Job: The Efficacy of a Short App-Based Mindfulness Intervention to Improve Sleep Quality and Quantity Within the Workforce. (2025) Daniel, Carole; Leyrat, Clémence; Gentina, Elodie; Mesmer-Magnus, Jessica; Guidice, Rebecca; Bailly, Sebastien picture_as_pdf

Trial emulation to assess the effect of surgery on survival when there are competing risks, with application to patients with thoracic aortic aneurysms. (2025) Murray, James; Chesang, Caroline; Large, Steve; Bicknell, Colin; Freeman, Carol; Keogh, Ruth H; Sharples, Linda D picture_as_pdf

Protocol for an adaptive platform trial of intended service user-derived interventions to equitably reduce non-attendance in eye screening programmes in Botswana, India, Kenya and Nepal. (2025) Allen, Luke; Kim, Min; Tlhajoane, Malebogo; Macleod, David; Nkomazana, Oathokwa; Gichangi, Michael; Mishra, Sailesh; Sabherwal, Shalinder; Carpenter, James R; Karanja, Sarah; Ho-Foster, Ari; Ratshaa, Bakgaki; Bolster, Nigel; Ramke, Jacqueline; Burton, Matthew J; Bastawrous, Andrew

Systematic Review, Meta-Analysis, and Population Study to Determine the Biologic Sex Ratio in Dilated Cardiomyopathy. (2025) Bergan, Natalie; Prachee, Ishika; Curran, Lara; McGurk, Kathryn A; Lu, Chang; de Marvao, Antonio; Bai, Wenjia; Halliday, Brian P; Gregson, John; O'Regan, Declan P; Ware, James S; Tayal, Upasana

Guidance for protocol content and reporting of factorial randomised trials: explanation and elaboration of the CONSORT 2010 and SPIRIT 2013 extensions. (2025) Kahan, Brennan C; Juszczak, Edmund; Beller, Elaine; Birchenall, Megan; Chan, An-Wen; Hall, Sophie; Little, Paul; Fletcher, John; Golub, Robert M; Goulao, Beatriz; Hopewell, Sally; Islam, Nazrul; Zwarenstein, Merrick; Elbourne, Diana; Montgomery, Alan

Potential interactions between digoxin and direct oral anticoagulants: application of cohort & novel case-crossover designs. (2025) Wong, Angel YS; Warren-Gash, Charlotte; Bhaskaran, Krishnan; Leyrat, Clémence; Banerjee, Amitava; Smeeth, Liam; Douglas, Ian J picture_as_pdf

Medical therapy and outcomes in REVIVED-BCIS2 and STICHES: an individual patient data analysis. (2025) Ryan, Matthew; Petrie, Mark C; Kontopantelis, Evangelos; Dodd, Matthew; Tong, Guangyu; Marquis-Gravel, Guillaume; Docherty, Kieran F; Clayton, Tim; Lansky, Alexandra J; Mamas, Mamas A; Rouleau, Jean-Lucien; Velazquez, Eric J; Perera, Divaka picture_as_pdf

Comparison of Investigator-Reported and Centrally Adjudicated Heart Failure Outcomes in the EMPEROR-Preserved Trial. (2025) Carson, Peter; Teerlink, John R; Komajda, Michel; Anand, Inder; Packer, Milton; Butler, Javed; Doehner, Wolfram; Ferreira, João Pedro; Filippatos, Gerasimos; Haass, Markus; Miller, Alan; Pehrson, Steen; Pocock, Stuart J; Iwata, Tomoko; Brueckmann, Martina; Gasior, Tomasz; Zannad, Faiez; Anker, Stefan D picture_as_pdf

Impact of patient sex on selection for abdominal aortic aneurysm repair: a discrete choice experiment. (2025) Pouncey, Anna Louise; Loría-Rebolledo, Luis Enrique; Sharples, Linda; Bicknell, Colin; Ryan, Mandy; Powell, Janet picture_as_pdf

24-week, all-oral regimens for pulmonary rifampicin-resistant tuberculosis in TB-PRACTECAL trial sites: an economic evaluation. (2025) Sweeney, Sedona; Laurence, Yoko V; Berry, Catherine; Singh, Maninder Pal; Dodd, Matthew; Fielding, Katherine; Kazounis, Emil; Moodliar, Ronelle; Solodovnikova, Varvara; Tigay, Zinaida; Liverko, Irina; Parpieva, Nargiza; Butabekov, Ilhomjon; Usmanova, Ruzilya; Rassool, Mohammed; Motta, Ilaria; Nyangweso, George Mokua; Jolivet, Pascal; Abdrasuliev, Tleubergen; Moe, Soe; Aw, Pei Sun; Samieva, Nazgul; Nyang'wa, Bern-Thomas picture_as_pdf

Guidelines for the content of statistical analysis plans in clinical trials: protocol for an extension to cluster randomized trials. (2025) Hemming, Karla; Thompson, Jacqueline Y; Hooper, Richard L; Ukoumunne, Obioha C; Li, Fan; Caille, Agnes; Kahan, Brennan C; Leyrat, Clemence; Grayling, Michael J; Mohammed, Nuredin I; Thompson, Jennifer A; Giraudeau, Bruno; Turner, Elizabeth L; Watson, Samuel I; Goulão, Beatriz; Kasza, Jessica; Forbes, Andrew B; Copas, Andrew J; Taljaard, Monica picture_as_pdf

Mixed-methods study to develop extensions to the SPIRIT and CONSORT statements for factorial randomised trials: the Reporting Factorial Trials (RAFT) study. (2025) Hall, Sophie S; Juszczak, Edmund; Birchenall, Megan; Elbourne, Diana; Beller, Elaine; Chan, An-Wen; Little, Paul; Montgomery, Alan A; Kahan, Brennan C picture_as_pdf

Evaluation of a peer support group programme for vulnerable host population and refugees living with diabetes and/or hypertension in Lebanon: a before-after study. (2025) Sanga, Leah Anku; Njeim, Carla; Ansbro, Éimhín; Naimi, Rima Kighsro; Ibrahim, Ali; Schmid, Benjamin; Diab, Jasmin Lilian; Roswall, Jytte; Clayton, Tim; Larsen, Lars Bruun; Perel, Pablo picture_as_pdf

The Data Monitoring Experience in Empagliflozin Randomized Clinical Trials Between 2011 and 2024. (2025) Welty, Francine K; Parhofer, Klaus G; Konstam, Marvin; Palmer, Michael K; Greenberg, Barry; Daher, Ralph; Clayton, Tim picture_as_pdf

Effect of prenatal multiple micronutrient supplementation on birth weight in Ethiopia: protocol for a pragmatic cluster-randomised trial. (2025) Marchant, Tanya; Alemayehu, Senait; Asfaw, Elias; Daba, Alemneh Kabeta; Defar, Atkure; Opondo, Charles; Persson, Lars Ake; Schellenberg, Joanna; Taye, Girum; Tesfa, Anene; Tessema, Bedasa; Zenebe, Kalkidan; Tessema, Masresha picture_as_pdf

Piloting Multiple Micronutrient Supplementation Within the Routine Antenatal Care System in Ethiopia: Insights From Stakeholders. (2025) Berhanu, Anene Tesfa; Defar, Atkure; Taye, Girum; Daba, Alemneh Kabeta; Alemayehu, Senait; Tessema, Bedasa; Zenebe, Kalkidan; Opondo, Charles; Tollera, Getachew; Hailu, Mesay; Schellenberg, Joanna; Persson, Lars Ake; Marchant, Tanya; Tessema, Masresha picture_as_pdf

Weight gain among children under five with severe malnutrition in therapeutic feeding programmes: a systematic review and meta-analysis. (2025) O'Donovan, Grace; Allen, Daniel; Nkosi-Gondwe, Thandile; Anujuo, Kenneth; Abera, Mubarek; Kirolos, Amir; Olga, Laurentya; Thompson, Debbie; McKenzie, Kimberley; Wimborne, Elizabeth; Cole, Tim J; Koulman, Albert; Lelijveld, Natasha; Crampin, Amelia C; CHANGE Study Collaborators Group; Opondo, Charles; Kerac, Marko picture_as_pdf

Longitudinal leucocyte DNA methylation changes in Mesoamerican nephropathy. (2025) Oomatia, Amin; Chervova, Olga; Al-Rashed, Ali M; Smpokou, Evangelia-Theano; Ecker, Simone; Pearce, Neil; Heggeseth, Brianna; Nitsch, Dorothea; Cardenas, Andres; Beck, Stephan; Gonzalez-Quiroz, Marvin; Caplin, Ben picture_as_pdf

G-formula with multiple imputation for causal inference with incomplete data. (2025) Bartlett, Jonathan W; Olarte Parra, Camila; Granger, Emily; Keogh, Ruth H; van Zwet, Erik W; Daniel, Rhian M

Potential interactions between antimicrobials and direct oral anticoagulants: Population-based cohort and case-crossover study. (2025) Wong, Angel YS; Warren-Gash, Charlotte; Bhaskaran, Krishnan; Leyrat, Clémence; Banerjee, Amitava; Smeeth, Liam; Douglas, Ian J picture_as_pdf

Applying the Estimands Framework to Non-Inferiority Trials: Guidance on Choice of Hypothetical Estimands for Non-Adherence and Comparison of Estimation Methods. (2025) Morgan, Katy E; White, Ian R; Leyrat, Clémence; Stanworth, Simon; Kahan, Brennan C picture_as_pdf

Estimating hypothetical estimands with causal inference and missing data estimators in a diabetes trial case study. (2025) Olarte Parra, Camila; Daniel, Rhian M; Wright, David; Bartlett, Jonathan W

A global meta-analysis of gonorrhoea and chlamydia prevalence among men who have sex with men from 2000 to 2022. (2025) Davies, Ella P; Tsuboi, Motoyuki; Evans, Jayne; Rowley, Jane; Korenromp, Eline L; Clayton, Tim; Chico, R Matthew

Factors associated with sexually transmitted reinfections, number of sexual partners and condom use among previously infected young people. (2025) Landray, Isobel; Carpenter, James R; Berendes, Sima; Palmer, Melissa J; Free, Caroline

Coordinated expression of BMP10/ALK1/endoglin-proteins that drive embryonic cardiac and vascular morphogenesis-in patients with heart failure: The EMPEROR Program. (2025) Packer, Milton; Butler, Javed; Ferreira, João Pedro; Siddiqi, Tariq Jamal; Januzzi, James L; Sattar, Naveed; Maldonado, Sandra González; Panova-Noeva, Marina; Prochaska, Jürgen H; Sumin, Mikhail; Masson, Serge; Pocock, Stuart J; Filippatos, Gerasimos; Anker, Stefan D; Zannad, Faiez

Effectiveness of the GRACE risk score according to troponin elevation in patients admitted with non-ST elevation acute coronary syndrome: a post hoc analysis of the UKGRIS parallel group cluster randomised controlled trial. (2025) Gale, Chris P; Stocken, Deborah; Nadarajah, Ramesh; Aktaa, Suleman; Reynolds, Catherine; Gilberts, Rachael; Brieger, David B; Carruthers, Kathryn; Chew, Derek P; Goodman, Shaun; Fernandez, Catherine; Sharples, Linda; Yan, Andrew T; Fox, Keith AA

Doctors taking bribes from pharmaceutical companies is common and not substantially reduced by an educational intervention: a pragmatic randomised controlled trial in Pakistan. (2025) Khan, Mishal; Noor, Muhammad Naveed; Rahman-Shepherd, Afifah; Siddiqui, Amna Rehana; Khan, Sabeen Sharif; van der Mark, Nina; Isani, Afshan Khurshid; Siddiqi, Ahson Q; Opondo, Charles; Ziauddin, Faisal; Bhutto, Faiza; Azam, Iqbal; Hanefeld, Johanna; Ali, Natasha; Khan, Robyna Irshad; Kazmi, Syed Ahmed Raza; Wiseman, Virginia; Aftab, Wafa; Mirza, Zafar; Hasan, Zainab; Siddiqi, Sameen; Hasan, Rumina; Shakoor, Sadia

Randomised feasibility study of an intestinal adsorbent in acute diarrhoea in The Gambia. (2025) Rahden, Paul; Fatty, Abdoulie; Jobarteh, Momodou Lamin; Sallah, Abdoulwahab; Jaiteh, Ebrahim; Allen, Angela; Umoh, Doreen; Bass, Fanta; Dodd, Matthew; Howell, Carol; Markaryan, Elena; Hnatič, Radovan; Allen, Stephen

Tranexamic acid for preventing postpartum haemorrhage after vaginal birth. (2025) Rohwer, Christa; Rohwer, Anke C; Cluver, Catherine; Ker, Katharine; Hofmeyr, G Justus

Analytical approaches to evaluate risk factors of multimorbidity: a systematic scoping review protocol. (2025) Song, Wenbo; Birk, Nick; Matsuzaki, Mika; Lieber, Judith; Yamanashi, Hirotomo; Rogers, Elliott; Aramrat, Chanchanok; Wiwatkunupakarn, Nutchar; Angkurawaranon, Chaisiri; Lewin, Alex; Kinra, Sanjay; Mallinson, Poppy Alice Carson

The association between proton pump inhibitors and the risk of gastrointestinal bleeding in oral anticoagulants users. (2025) Wang, Zixuan; Yu, Qiuyan; Warren-Gash, Charlotte; Bhaskaran, Krishnan; Leyrat, Clémence; Cheung, Ka Shing; Chui, Celine SL; Chan, Esther W; Wong, Ian CK; Banerjee, Amitava; Smeeth, Liam; Douglas, Ian J; Wong, Angel YS

Conference or Workshop Item

REAPPRAISED checklist can detect research integrity issues. (2025) Henley, Patricia

Thesis

Estimating treatment effects on mortality and competing risks using real-world data, with application to prostate cancer. (2025) Chesang, C

Statistical Methods for Handling Non-adherence to Interventions in Randomised Non-inferiority Trials. (2025) Dodd, M picture_as_pdf