Phelan, Jody; Van den Heede, Klaas; Masyn, Serge; Verbeeck, Rudi; Lamprecht, Dirk A; Koul, Anil; Wall, Richard J; (2024) An open-access dashboard to interrogate the genetic diversity of Mycobacterium tuberculosis clinical isolates. Scientific reports, 14 (1). 24792-. ISSN 2045-2322 DOI: https://doi.org/10.1038/s41598-024-75818-y

Trenaman, Anna; Tinti, Michele; Wall, Richard J; Horn, David; (2024) Post-transcriptional reprogramming by thousands of mRNA untranslated regions in trypanosomes. Nature communications, 15 (1). 8113-. ISSN 2041-1723 DOI: https://doi.org/10.1038/s41467-024-52432-0

Braillard, Stéphanie; Keenan, Martine; Breese, Karen J; Heppell, Jacob; Abbott, Michael; Islam, Rafiqul; Shackleford, David M; Katneni, Kasiram; Crighton, Elly; Chen, Gong; +28 more... Patil, Rahul; Lee, Given; White, Karen L; Carvalho, Sandra; Wall, Richard J; Chemi, Giulia; Zuccotto, Fabio; González, Silvia; Marco, Maria; Deakyne, Julianna; Standing, David; Brunori, Gino; Lyon, Jonathan J; Castañeda-Casado, Pablo; Camino, Isabel; Martinez Martinez, Maria S; Zulfiqar, Bilal; Avery, Vicky M; Feijens, Pim-Bart; Van Pelt, Natascha; Matheeussen, An; Hendrickx, Sarah; Maes, Louis; Caljon, Guy; Yardley, Vanessa; Wyllie, Susan; Charman, Susan A; Chatelain, Eric; (2023) DNDI-6174 is a preclinical candidate for visceral leishmaniasis that targets the cytochrome bc1. Science translational medicine, 15 (726). eadh9902-. ISSN 1946-6234 DOI: https://doi.org/10.1126/scitranslmed.adh9902

Cleghorn, Laura AT; Wall, Richard J; Albrecht, Sébastien; MacGowan, Stuart A; Norval, Suzanne; De Rycker, Manu; Woodland, Andrew; Spinks, Daniel; Thompson, Stephen; Patterson, Stephen; +12 more... Corpas Lopez, Victoriano; Dey, Gourav; Collie, Iain T; Hallyburton, Irene; Kime, Robert; Simeons, Frederick RC; Stojanovski, Laste; Frearson, Julie A; Wyatt, Paul G; Read, Kevin D; Gilbert, Ian H; Wyllie, Susan; (2023) Development of a 2,4-Diaminothiazole Series for the Treatment of Human African Trypanosomiasis Highlights the Importance of Static-Cidal Screening of Analogues. Journal of medicinal chemistry, 66 (13). pp. 8896-8916. ISSN 0022-2623 DOI: https://doi.org/10.1021/acs.jmedchem.3c00509

González, Silvia; Wall, Richard J; Thomas, John; Braillard, Stephanie; Brunori, Gino; Camino Díaz, Isabel; Cantizani, Juan; Carvalho, Sandra; Castañeda Casado, Pablo; Chatelain, Eric; +20 more... Cotillo, Ignacio; Fiandor, Jose M; Francisco, Amanda Fortes; Grimsditch, David; Keenan, Martine; Kelly, John M; Kessler, Albane; Luise, Chiara; Lyon, Jon J; MacLean, Lorna; Marco, Maria; Martin, J Julio; Martinez Martinez, Maria S; Paterson, Christy; Read, Kevin D; Santos-Villarejo, Angel; Zuccotto, Fabio; Wyllie, Susan; Miles, Tim J; De Rycker, Manu; (2023) Short-course combination treatment for experimental chronic Chagas disease. Science translational medicine, 15 (726). eadg8105-. ISSN 1946-6234 DOI: https://doi.org/10.1126/scitranslmed.adg8105

Lima, Marta L; Tulloch, Lindsay B; Corpas-Lopez, Victoriano; Carvalho, Sandra; Wall, Richard J; Milne, Rachel; Rico, Eva; Patterson, Stephen; Gilbert, Ian H; Moniz, Sonia; +6 more... MacLean, Lorna; Torrie, Leah S; Morgillo, Carmine; Horn, David; Zuccotto, Fabio; Wyllie, Susan; (2022) Identification of a Proteasome-Targeting Arylsulfonamide with Potential for the Treatment of Chagas' Disease. Antimicrobial agents and chemotherapy, 66 (1). e0153521-. ISSN 0066-4804 DOI: https://doi.org/10.1128/AAC.01535-21

Milne, Rachel; Wiedemar, Natalie; Corpas-Lopez, Victoriano; Moynihan, Eoin; Wall, Richard J; Dawson, Alice; Robinson, David A; Shepherd, Sharon M; Smith, Robert J; Hallyburton, Irene; +7 more... Post, John M; Dowers, Karen; Torrie, Leah S; Gilbert, Ian H; Baragaña, Beatriz; Patterson, Stephen; Wyllie, Susan; (2022) Toolkit of Approaches To Support Target-Focused Drug Discovery for Plasmodium falciparum Lysyl tRNA Synthetase. ACS infectious diseases, 8 (9). pp. 1962-1974. ISSN 2373-8227 DOI: https://doi.org/10.1021/acsinfecdis.2c00364

Ngum, Neville M; Aziz, Muhammad YA; Mohammed Latif, Liaque; Wall, Richard J; Duce, Ian R; Mellor, Ian R; (2022) Non-canonical endogenous expression of voltage-gated sodium channel NaV 1.7 subtype by the TE671 rhabdomyosarcoma cell line. The Journal of physiology, 600 (10). pp. 2499-2513. ISSN 0022-3751 DOI: https://doi.org/10.1113/JP283055

Smith, Alasdair; Wall, Richard J; Patterson, Stephen; Rowan, Tim; Rico Vidal, Eva; Stojanovski, Laste; Huggett, Margaret; Hampton, Shahienaz E; Thomas, Michael G; Corpas Lopez, Victoriano; +19 more... Gillingwater, Kirsten; Duke, Jeff; Napier, Grant; Peter, Rose; Vitouley, Hervé S; Harrison, Justin R; Milne, Rachel; Jeacock, Laura; Baker, Nicola; Davis, Susan H; Simeons, Frederick; Riley, Jennifer; Horn, David; Brun, Reto; Zuccotto, Fabio; Witty, Michael J; Wyllie, Susan; Read, Kevin D; Gilbert, Ian H; (2022) Repositioning of a Diaminothiazole Series Confirmed to Target the Cyclin-Dependent Kinase CRK12 for Use in the Treatment of African Animal Trypanosomiasis. Journal of medicinal chemistry, 65 (7). pp. 5606-5624. ISSN 0022-2623 DOI: https://doi.org/10.1021/acs.jmedchem.1c02104

Mowbray, Charles E; Braillard, Stéphanie; Glossop, Paul A; Whitlock, Gavin A; Jacobs, Robert T; Speake, Jason; Pandi, Bharathi; Nare, Bakela; Maes, Louis; Yardley, Vanessa; +12 more... Freund, Yvonne; Wall, Richard J; Carvalho, Sandra; Bello, Davide; Van den Kerkhof, Magali; Caljon, Guy; Gilbert, Ian H; Corpas-Lopez, Victoriano; Lukac, Iva; Patterson, Stephen; Zuccotto, Fabio; Wyllie, Susan; (2021) DNDI-6148: A Novel Benzoxaborole Preclinical Candidate for the Treatment of Visceral Leishmaniasis. Journal of Medicinal Chemistry, 64 (21). pp. 16159-16176. ISSN 0022-2623 DOI: https://doi.org/10.1021/acs.jmedchem.1c01437

Paradela, Luciana S; Wall, Richard J; Carvalho, Sandra; Chemi, Giulia; Corpas-Lopez, Victoriano; Moynihan, Eoin; Bello, Davide; Patterson, Stephen; Güther, Maria Lucia S; Fairlamb, Alan H; +5 more... Ferguson, Michael AJ; Zuccotto, Fabio; Martin, Julio; Gilbert, Ian H; Wyllie, Susan; (2021) Multiple unbiased approaches identify oxidosqualene cyclase as the molecular target of a promising anti-leishmanial. Cell Chemical Biology, 28 (5). 711-721.e8. ISSN 2451-9456 DOI: https://doi.org/10.1016/j.chembiol.2021.02.008

Van den Kerkhof, Magali; Leprohon, Philippe; Mabille, Dorien; Hendrickx, Sarah; Tulloch, Lindsay B; Wall, Richard J; Wyllie, Susan; Chatelain, Eric; Mowbray, Charles E; Braillard, Stéphanie; +3 more... Ouellette, Marc; Maes, Louis; Caljon, Guy; (2021) Identification of Resistance Determinants for a Promising Antileishmanial Oxaborole Series. Microorganisms, 9 (7). p. 1408. ISSN 2076-2607 DOI: https://doi.org/10.3390/microorganisms9071408

Pandey, Rajan; Abel, Steven; Boucher, Matthew; Wall, Richard J; Zeeshan, Mohammad; Rea, Edward; Freville, Aline; Lu, Xueqing Maggie; Brady, Declan; Daniel, Emilie; +9 more... Stanway, Rebecca R; Wheatley, Sally; Batugedara, Gayani; Hollin, Thomas; Bottrill, Andrew R; Gupta, Dinesh; Holder, Anthony A; Le Roch, Karine G; Tewari, Rita; (2020) Plasmodium Condensin Core Subunits SMC2/SMC4 Mediate Atypical Mitosis and Are Essential for Parasite Proliferation and Transmission. CELL REPORTS, 30 (6). 1883-1897.e6. ISSN 2211-1247 DOI: https://doi.org/10.1016/j.celrep.2020.01.033

Wall, Richard J; Ferguson, David JP; Freville, Aline; Franke-Fayard, Blandine; Brady, Declan; Zeeshan, Mohammad; Bottrill, Andrew R; Wheatley, Sally; Fry, Andrew M; Janse, Chris J; +4 more... Yamano, Hiroyuki; Holder, Anthony A; Guttery, David S; Tewari, Rita; (2018) Plasmodium APC3 mediates chromosome condensation and cytokinesis during atypical mitosis in male gametogenesis. SCIENTIFIC REPORTS, 8 (1). 5610-. ISSN 2045-2322 DOI: https://doi.org/10.1038/s41598-018-23871-9

Green, Judith L; Wall, Richard J; Vahokoski, Juha; Yusuf, Noor A; Ridzuan, Mohd A Mohd; Stanway, Rebecca R; Stock, Jessica; Knuepfer, Ellen; Brady, Declan; Martin, Stephen R; +7 more... Howell, Steven A; Pires, Isa P; Moon, Robert W; Molloy, Justin E; Kursula, Inari; Tewari, Rita; Holder, Anthony A; (2017) Compositional and expression analyses of the glideosome during the Plasmodium life cycle reveal an additional myosin light chain required for maximum motility. The Journal of biological chemistry, 292 (43). pp. 17857-17875. ISSN 0021-9258 DOI: https://doi.org/10.1074/jbc.M117.802769

Yusuf, Noor A; Green, Judith L; Wall, Richard J; Knuepfer, Ellen; Moon, Robert W; Schulte-Huxel, Christina; Stanway, Rebecca R; Martin, Stephen R; Howell, Steven A; Douse, Christopher H; +4 more... Cota, Ernesto; Tate, Edward W; Tewari, Rita; Holder, Anthony A; (2015) The Plasmodium Class XIV Myosin, MyoB, Has a Distinct Subcellular Location in Invasive and Motile Stages of the Malaria Parasite and an Unusual Light Chain. The Journal of biological chemistry, 290 (19). pp. 12147-12164. ISSN 0021-9258 DOI: https://doi.org/10.1074/jbc.M115.637694