Costa, Fernanda Cristina; Francisco, Amanda Fortes; Jayawardhana, Shiromani; Calderano, Simone Guedes; Lewis, Michael D; Olmo, Francisco; Beneke, Tom; Gluenz, Eva; Sunter, Jack; Dean, Samuel; +2 more... Kelly, John Morrison; Taylor, Martin Craig; (2018) Expanding the toolbox for Trypanosoma cruzi: A parasite line incorporating a bioluminescence-fluorescence dual reporter and streamlined CRISPR/Cas9 functionality for rapid in vivo localisation and phenotyping. PLoS neglected tropical diseases, 12 (4). e0006388-. ISSN 1935-2727 DOI: https://doi.org/10.1371/journal.pntd.0006388

Francisco, Amanda Fortes; Jayawardhana, Shiromani; Taylor, Martin C; Lewis, Michael D; Kelly, John M; (2018) Assessing the Effectiveness of Curative Benznidazole Treatment in Preventing Chronic Cardiac Pathology in Experimental Models of Chagas Disease. Antimicrobial agents and chemotherapy, 62 (10). ISSN 0066-4804 DOI: https://doi.org/10.1128/AAC.00832-18

Lewis, Michael D; Francisco, Amanda F; Jayawardhana, Shiromani; Langston, Harry; Taylor, Martin C; Kelly, John M; (2018) Imaging the development of chronic Chagas disease after oral transmission. Scientific reports, 8 (1). 11292-. ISSN 2045-2322 DOI: https://doi.org/10.1038/s41598-018-29564-7

Brand, Stephen; Ko, Eun Jung; Viayna, Elisabet; Thompson, Stephen; Spinks, Daniel; Thomas, Michael; Sandberg, Lars; Francisco, Amanda F; Jayawardhana, Shiromani; Smith, Victoria C; +26 more... Jansen, Chimed; De Rycker, Manu; Thomas, John; MacLean, Lorna; Osuna-Cabello, Maria; Riley, Jennifer; Scullion, Paul; Stojanovski, Laste; Simeons, Frederick RC; Epemolu, Ola; Shishikura, Yoko; Crouch, Sabrinia D; Bakshi, Tania S; Nixon, Christopher J; Reid, Iain H; Hill, Alan P; Underwood, Tim Z; Hindley, Sean J; Robinson, Sharon A; Kelly, John M; Fiandor, Jose M; Wyatt, Paul G; Marco, Maria; Miles, Timothy J; Read, Kevin D; Gilbert, Ian H; (2017) Discovery and Optimization of 5-Amino-1,2,3-triazole-4-carboxamide Series against Trypanosoma cruzi. Journal of medicinal chemistry, 60 (17). pp. 7284-7299. ISSN 0022-2623 DOI: https://doi.org/10.1021/acs.jmedchem.7b00463

Francisco, Amanda F; Jayawardhana, Shiromani; Lewis, Michael D; Taylor, Martin C; Kelly, John M; (2017) Biological factors that impinge on Chagas disease drug development. Parasitology, 144 (14). pp. 1871-1880. ISSN 0031-1820 DOI: https://doi.org/10.1017/S0031182017001469

Francisco, Amanda Fortes; Jayawardhana, Shiromani; Lewis, Michael D; White, Karen L; Shackleford, David M; Chen, Gong; Saunders, Jessica; Osuna-Cabello, Maria; Read, Kevin D; Charman, Susan A; +2 more... Chatelain, Eric; Kelly, John M; (2016) Nitroheterocyclic drugs cure experimental Trypanosoma cruzi infections more effectively in the chronic stage than in the acute stage. Scientific reports, 6 (1). 35351-. ISSN 2045-2322 DOI: https://doi.org/10.1038/srep35351

Kishore, Kranti G; Ghashghaei, Ouldouz; Estarellas, Carolina; Mestre, M Mar; Monturiol, Cristina; Kielland, Nicola; Kelly, John M; Francisco, Amanda Fortes; Jayawardhana, Shiromani; Muñoz-Torrero, Diego; +4 more... Pérez, Belén; Luque, F Javier; Gámez-Montaño, Rocío; Lavilla, Rodolfo; (2016) Insertion of Isocyanides into N-Si Bonds: Multicomponent Reactions with Azines Leading to Potent Antiparasitic Compounds. Angewandte Chemie (International ed in English), 55 (31). pp. 8994-8998. ISSN 1433-7851 DOI: https://doi.org/10.1002/anie.201604109

Kishore, Kranti G; Ghashghaei, Ouldouz; Estarellas, Carolina; Mestre, M Mar; Monturiol, Cristina; Kielland, Nicola; Kelly, John M; Francisco, Amanda Fortes; Jayawardhana, Shiromani; Muñoz-Torrero, Diego; +4 more... Pérez, Belén; Luque, F Javier; Gámez-Montaño, Rocío; Lavilla, Rodolfo; (2016) Insertion of Isocyanides into N-Si Bonds: Multicomponent Reactions with Azines Leading to Potent Antiparasitic Compounds. Angewandte Chemie, 55 (31). pp. 8994-8998. ISSN 0044-8249 DOI: https://doi.org/10.1002/anie.201604109

Lewis, Michael D; Francisco, Amanda Fortes; Taylor, Martin C; Jayawardhana, Shiromani; Kelly, John M; (2016) Host and parasite genetics shape a link between Trypanosoma cruzi infection dynamics and chronic cardiomyopathy. Cellular microbiology, 18 (10). pp. 1429-1443. ISSN 1462-5814 DOI: https://doi.org/10.1111/cmi.12584

Francisco, Amanda Fortes; Lewis, Michael D; Jayawardhana, Shiromani; Taylor, Martin C; Chatelain, Eric; Kelly, John M; (2015) Limited Ability of Posaconazole To Cure both Acute and Chronic Trypanosoma cruzi Infections Revealed by Highly Sensitive In Vivo Imaging. Antimicrobial agents and chemotherapy, 59 (8). pp. 4653-4661. ISSN 0066-4804 DOI: https://doi.org/10.1128/AAC.00520-15

Francisco, Amanda Fortes; Lewis, Michael D; Jayawardhana, Shiromani; Taylor, Martin C; Chatelain, Eric; Kelly, John M; (2015) Reply to "Drug Susceptibility of Genetically Engineered Trypanosoma cruzi Strains and Sterile Cure in Animal Models as a Criterion for Potential Clinical Efficacy of Anti-T. cruzi Drugs". Antimicrobial agents and chemotherapy, 59 (12). 7925-. ISSN 0066-4804 DOI: https://doi.org/10.1128/AAC.02022-15