Items where Author is "Douglas, I"
Number of items: 201.
2025
Using Quantitative Bias Analysis to Adjust for Misclassification of COVID-19 Outcomes: An Applied Example of Inhaled Corticosteroids and COVID-19 Outcomes. (2025)
Bokern, Marleen; Rentsch, Christopher T; Quint, Jennifer K; Hunnicutt, Jacob; Douglas, Ian; Schultze, Anna
Potential interactions between antimicrobials and direct oral anticoagulants: Population-based cohort and case-crossover study. (2025)
Wong, Angel YS; Warren-Gash, Charlotte; Bhaskaran, Krishnan; Leyrat, Clémence; Banerjee, Amitava; Smeeth, Liam; Douglas, Ian J
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Potential interactions between digoxin and direct oral anticoagulants: application of cohort & novel case-crossover designs. (2025)
Wong, Angel YS; Warren-Gash, Charlotte; Bhaskaran, Krishnan; Leyrat, Clémence; Banerjee, Amitava; Smeeth, Liam; Douglas, Ian J
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2024
Comparative effectiveness of second line oral antidiabetic treatments among people with type 2 diabetes mellitus: emulation of a target trial using routinely collected health data. (2024)
Bidulka, Patrick; Lugo-Palacios, David G; Carroll, Orlagh; O'Neill, Stephen; Adler, Amanda I; Basu, Anirban; Silverwood, Richard J; Bartlett, Jonathan W; Nitsch, Dorothea; Charlton, Paul; Briggs, Andrew H; Smeeth, Liam; Douglas, Ian J; Khunti, Kamlesh; Grieve, Richard
Applying two approaches to detect unmeasured confounding due to time-varying variables in a self-controlled risk interval design evaluating COVID-19 vaccine safety signals, using myocarditis as a case example. (2024)
Bots, Sophie H; Belitser, Svetlana; Groenwold, Rolf HH; Durán, Carlos E; Riera-Arnau, Judit; Schultze, Anna; Messina, Davide; Segundo, Elena; Douglas, Ian; Carreras, Juan José; Garcia-Poza, Patricia; Gini, Rosa; Huerta, Consuelo; Martín-Pérez, Mar; Martin, Ivonne; Paoletti, Olga; Bissacco, Carlo Alberto; Correcher-Martínez, Elisa; Souverein, Patrick; Urchueguía-Fornes, Arantxa; Villalobos, Felipe; Sturkenboom, Miriam CJM; Klungel, Olaf H
Quantifying possible bias in clinical and epidemiological studies with quantitative bias analysis: common approaches and limitations. (2024)
Brown, Jeremy P; Hunnicutt, Jacob N; Ali, M Sanni; Bhaskaran, Krishnan; Cole, Ashley; Langan, Sinead M; Nitsch, Dorothea; Rentsch, Christopher T; Galwey, Nicholas W; Wing, Kevin; Douglas, Ian J
Core Concepts in Pharmacoepidemiology: Quantitative Bias Analysis. (2024)
Brown, Jeremy P; Hunnicutt, Jacob N; Ali, M Sanni; Bhaskaran, Krishnan; Cole, Ashley; Langan, Sinead M; Nitsch, Dorothea; Rentsch, Christopher T; Galwey, Nicholas W; Wing, Kevin; Douglas, Ian J
Systemic Fluoroquinolone Use and Risk of Uveitis or Retinal Detachment. (2024)
Brown, Jeremy P; Wing, Kevin; Evans, Stephen J; Leyrat, Clémence; Mansfield, Kathryn E; Smeeth, Liam; Wong, Angel YS; Yorston, David; Galwey, Nicholas W; Douglas, Ian J
Implementation of a Taxonomy-Based Framework for the Selection of Appropriate Drugs and Outcomes for Real-World Data Signal Detection Studies. (2024)
Coste, Astrid; Wong, Angel Ys; Warren-Gash, Charlotte; Matthewman, Julian; Bate, Andrew; Douglas, Ian J
Pooling of primary care electronic health record (EHR) data on Huntington's disease (HD) and cancer: establishing comparability of two large UK databases. (2024)
Dedman, Daniel; Williams, Rachael; Bhaskaran, Krishnan; Douglas, Ian J
A self-controlled case series study to measure the risk of SARS-CoV-2 infection associated with attendance at sporting and cultural events: the UK Events Research Programme events. (2024)
Douglas, Ian J; Peh, Jerlyn; Mansfield, Kathryn E; Trelfa, Anna; Fowler, Tom; Boulter, Matthew; Cleary, Paul; Smith, Jenifer; Edmunds, W John
Overcoming time-varying confounding in self-controlled case series with active comparators: application and recommendations. (2024)
Schultze, Anna; Brown, Jeremy; Logie, John; Cunnington, Marianne; Requena, Gema; Gillespie, Iain A; Evans, Stephen JW; Douglas, Ian; Galwey, Nicholas
A comparison of four self-controlled study designs in an analysis of COVID-19 vaccines and myocarditis using five European databases. (2024)
Schultze, Anna; Martin, Ivonne; Messina, Davide; Bots, Sophie; Belitser, Svetlana; José Carreras-Martínez, Juan; Correcher-Martinez, Elisa; Urchueguía-Fornes, Arantxa; Martín-Pérez, Mar; García-Poza, Patricia; Villalobos, Felipe; Pallejà-Millán, Meritxell; Alberto Bissacco, Carlo; Segundo, Elena; Souverein, Patrick; Riefolo, Fabio; Durán, Carlos E; Gini, Rosa; Sturkenboom, Miriam; Klungel, Olaf; Douglas, Ian
Sharing Is Caring? International Society for Pharmacoepidemiology Review and Recommendations for Sharing Programming Code. (2024)
Tazare, John; Wang, Shirley V; Gini, Rosa; Prieto-Alhambra, Daniel; Arlett, Peter; Morales Leaver, Daniel R; Morton, Caroline; Logie, John; Popovic, Jennifer; Donegan, Katherine; Schneeweiss, Sebastian; Douglas, Ian; Schultze, Anna
Real-world effectiveness of oral anticoagulants in the prevention of stroke: emulation and extension of the ARISTOTLE trial using UK EHRs. (2024)
Teoh, MEL
Potential interactions between medications for rate control and direct oral anticoagulants: Population-based cohort and case-crossover study. (2024)
Wong, Angel YS; Warren-Gash, Charlotte; Bhaskaran, Krishnan; Leyrat, Clémence; Banerjee, Amitava; Smeeth, Liam; Douglas, Ian J
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Antihypertensive Medications and Eczematous Dermatitis in Older Adults. (2024)
Ye, Morgan; Chan, Leslie N; Douglas, Ian; Margolis, David J; Langan, Sinéad M; Abuabara, Katrina
2023
Real-world effectiveness and adverse events caused by ACE inhibitors and ARBs for reduction in cardiovascular events with validation against the ONTARGET trial. (2023)
Baptiste, PJ
Application of methods for handling unmeasured confounding in pharmacoepidemiological studies. (2023)
Brown, JP
Association Between Fluoroquinolone Use and Hospitalization With Aortic Aneurysm or Aortic Dissection. (2023)
Brown, Jeremy P; Wing, Kevin; Leyrat, Clémence; Evans, Stephen J; Mansfield, Kathryn E; Wong, Angel YS; Smeeth, Liam; Galwey, Nicholas W; Douglas, Ian J
Association between living with children, vaccination, and outcomes from COVID-19: an OpenSAFELY cohort study of 12 million adults in England during 2021–22. (2023)
Cowling, Thomas E; Forbes, Harriet; Wing, Kevin; Tazare, John; Schultze, Anna; Morton, Caroline E; Bacon, Sebastian; MacKenna, Brian; Walker, Alex J; Hulme, Will; Bates, Chris; Mehrkar, Amir; Curtis, Helen J; Evans, David; Inglesby, Peter; Davy, Simon; Cockburn, Jonathan; Parry, John; Hester, Frank; Harper, Sam; Douglas, Ian J; Evans, Stephen JW; Bhaskaran, Krishnan; Williamson, Elizabeth J; Eggo, Rosalind M; Goldacre, Ben; Tomlinson, Laurie A
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Trends, variation, and clinical characteristics of recipients of antiviral drugs and neutralising monoclonal antibodies for covid-19 in community settings: retrospective, descriptive cohort study of 23.4 million people in OpenSAFELY. (2023)
Green, Amelia CA; Curtis, Helen J; Higgins, Rose; Nab, Linda; Mahalingasivam, Viyaasan; Smith, Rebecca M; Mehrkar, Amir; Inglesby, Peter; Drysdale, Henry; DeVito, Nicholas J; Croker, Richard; Rentsch, Christopher T; Bhaskaran, Krishnan; Tazare, John; Zheng, Bang; Andrews, Colm D; Bacon, Sebastian CJ; Davy, Simon; Dillingham, Iain; Evans, David; Fisher, Louis; Hickman, George; Hopcroft, Lisa EM; Hulme, William J; Massey, Jon; MacDonald, Orla; Morley, Jessica; Morton, Caroline E; Park, Robin Y; Walker, Alex J; Ward, Tom; Wiedemann, Milan; Bates, Christopher; Cockburn, Jonathan; Parry, John; Hester, Frank; Harper, Sam; Douglas, Ian J; Evans, Stephen JW; Goldacre, Ben; Tomlinson, Laurie A; MacKenna, Brian
Prevalent new user designs: A literature review of current implementation practice. (2023)
Tazare, John; Gibbons, Daniel C; Bokern, Marleen; Williamson, Elizabeth J; Gillespie, Iain A; Cunnington, Marianne; Logie, John; Douglas, Ian J
Comparative effectiveness of sotrovimab and molnupiravir for preventing severe COVID-19 outcomes in patients on kidney replacement therapy: observational study using the OpenSAFELY-UKRR and SRR databases. (2023)
Zheng, Bang; Campbell, Jacqueline; Carr, Edward J; Tazare, John; Nab, Linda; Mahalingasivam, Viyaasan; Mehrkar, Amir; Santhakumaran, Shalini; Steenkamp, Retha; Loud, Fiona; Lyon, Susan; Scanlon, Miranda; Hulme, William J; Green, Amelia CA; Curtis, Helen J; Fisher, Louis; Parker, Edward; Goldacre, Ben; Douglas, Ian; Evans, Stephen; MacKenna, Brian; Bell, Samira; Tomlinson, Laurie A; Nitsch, Dorothea; OpenSAFELY Collaborative and LH&W NCS (or CONVALESCENCE) Collabo
Comparative effectiveness of nirmatrelvir/ritonavir versus sotrovimab and molnupiravir for preventing severe COVID-19 outcomes in non-hospitalised high-risk patients during Omicron waves: observational cohort study using the OpenSAFELY platform. (2023)
Zheng, Bang; Tazare, John; Nab, Linda; Green, Amelia Ca; Curtis, Helen J; Mahalingasivam, Viyaasan; Herrett, Emily L; Costello, Ruth E; Eggo, Rosalind M; Speed, Victoria; Bacon, Sebastian Cj; Bates, Christopher; Parry, John; Cockburn, Jonathan; Hester, Frank; Harper, Sam; Schaffer, Andrea L; Hulme, William J; Mehrkar, Amir; Evans, Stephen Jw; MacKenna, Brian; Goldacre, Ben; Douglas, Ian J; Tomlinson, Laurie A; OpenSAFELY Collaborative
2022
Overall and cause-specific hospitalisation and death after COVID-19 hospitalisation in England: A cohort study using linked primary care, secondary care, and death registration data in the OpenSAFELY platform. (2022)
Bhaskaran, Krishnan; Rentsch, Christopher T; Hickman, George; Hulme, William J; Schultze, Anna; Curtis, Helen J; Wing, Kevin; Warren-Gash, Charlotte; Tomlinson, Laurie; Bates, Chris J; Mathur, Rohini; MacKenna, Brian; Mahalingasivam, Viyaasan; Wong, Angel; Walker, Alex J; Morton, Caroline E; Grint, Daniel; Mehrkar, Amir; Eggo, Rosalind M; Inglesby, Peter; Douglas, Ian J; McDonald, Helen I; Cockburn, Jonathan; Williamson, Elizabeth J; Evans, David; Parry, John; Hester, Frank; Harper, Sam; Evans, Stephen Jw; Bacon, Sebastian; Smeeth, Liam; Goldacre, Ben
Ethnic and socioeconomic disparities in initiation of second-line antidiabetic treatment for people with type 2 diabetes in England: A cross-sectional study. (2022)
Bidulka, Patrick; Mathur, Rohini; Lugo-Palacios, David G; O'Neill, Stephen; Basu, Anirban; Silverwood, Richard J; Charlton, Paul; Briggs, Andrew; Smeeth, Liam; Adler, Amanda I; Douglas, Ian J; Khunti, Kamlesh; Grieve, Richard
Myocarditis and pericarditis associated with SARS-CoV-2 vaccines: A population-based descriptive cohort and a nested self-controlled risk interval study using electronic health care data from four European countries. (2022)
Bots, Sophie H; Riera-Arnau, Judit; Belitser, Svetlana V; Messina, Davide; Aragón, Maria; Alsina, Ema; Douglas, Ian J; Durán, Carlos E; García-Poza, Patricia; Gini, Rosa; Herings, Ron MC; Huerta, Consuelo; Sisay, Malede Mequanent; Martín-Pérez, Mar; Martin, Ivonne; Overbeek, Jetty A; Paoletti, Olga; Pallejà-Millán, Meritxell; Schultze, Anna; Souverein, Patrick; Swart, Karin MA; Villalobos, Felipe; Klungel, Olaf H; Sturkenboom, Miriam CJM
Proton pump inhibitors and myocardial infarction: an application of active comparators in a self-controlled case series. (2022)
Chui, Celine SL; Cheung, Ka Shing; Brown, Jeremy P; Douglas, Ian J; Wong, Ian CK; Chan, Esther W; Wong, Angel YS
Methods for drug safety signal detection using routinely collected observational electronic health care data: A systematic review. (2022)
Coste, Astrid; Wong, Angel; Bokern, Marleen; Bate, Andrew; Douglas, Ian J
Recording of 'COVID-19 vaccine declined': a cohort study on 57.9 million National Health Service patients' records in situ using OpenSAFELY, England, 8 December 2020 to 25 May 2021. (2022)
Curtis, Helen J; Inglesby, Peter; MacKenna, Brian; Croker, Richard; Hulme, William J; Rentsch, Christopher T; Bhaskaran, Krishnan; Mathur, Rohini; Morton, Caroline E; Bacon, Sebastian Cj; Smith, Rebecca M; Evans, David; Mehrkar, Amir; Tomlinson, Laurie; Walker, Alex J; Bates, Christopher; Hickman, George; Ward, Tom; Morley, Jessica; Cockburn, Jonathan; Davy, Simon; Williamson, Elizabeth J; Eggo, Rosalind M; Parry, John; Hester, Frank; Harper, Sam; O'Hanlon, Shaun; Eavis, Alex; Jarvis, Richard; Avramov, Dima; Griffiths, Paul; Fowles, Aaron; Parkes, Nasreen; Evans, Stephen Jw; Douglas, Ian J; Smeeth, Liam; Goldacre, Ben
Primary prevention of acute cardiovascular events by influenza vaccination: an observational study. (2022)
Davidson, Jennifer A; Banerjee, Amitava; Douglas, Ian; Leyrat, Clémence; Pebody, Richard; McDonald, Helen I; Herrett, Emily; Forbes, Harriet; Smeeth, Liam; Warren-Gash, Charlotte
Comparative effectiveness of ChAdOx1 versus BNT162b2 covid-19 vaccines in health and social care workers in England: cohort study using OpenSAFELY. (2022)
Hulme, William J; Williamson, Elizabeth J; Green, Amelia CA; Bhaskaran, Krishnan; McDonald, Helen I; Rentsch, Christopher T; Schultze, Anna; Tazare, John; Curtis, Helen J; Walker, Alex J; Tomlinson, Laurie A; Palmer, Tom; Horne, Elsie MF; MacKenna, Brian; Morton, Caroline E; Mehrkar, Amir; Morley, Jessica; Fisher, Louis; Bacon, Sebastian CJ; Evans, David; Inglesby, Peter; Hickman, George; Davy, Simon; Ward, Tom; Croker, Richard; Eggo, Rosalind M; Wong, Angel YS; Mathur, Rohini; Wing, Kevin; Forbes, Harriet; Grint, Daniel J; Douglas, Ian J; Evans, Stephen JW; Smeeth, Liam; Bates, Chris; Cockburn, Jonathan; Parry, John; Hester, Frank; Harper, Sam; Sterne, Jonathan AC; Hernán, Miguel A; Goldacre, Ben
Risk of severe COVID-19 outcomes associated with immune-mediated inflammatory diseases and immune-modifying therapies: a nationwide cohort study in the OpenSAFELY platform. (2022)
MacKenna, Brian; Kennedy, Nicholas A; Mehrkar, Amir; Rowan, Anna; Galloway, James; Matthewman, Julian; Mansfield, Kathryn E; Bechman, Katie; Yates, Mark; Brown, Jeremy; Schultze, Anna; Norton, Sam; Walker, Alex J; Morton, Caroline E; Harrison, David; Bhaskaran, Krishnan; Rentsch, Christopher T; Williamson, Elizabeth; Croker, Richard; Bacon, Seb; Hickman, George; Ward, Tom; Davy, Simon; Green, Amelia; Fisher, Louis; Hulme, William; Bates, Chris; Curtis, Helen J; Tazare, John; Eggo, Rosalind M; Evans, David; Inglesby, Peter; Cockburn, Jonathan; McDonald, Helen I; Tomlinson, Laurie A; Mathur, Rohini; Wong, Angel YS; Forbes, Harriet; Parry, John; Hester, Frank; Harper, Sam; Douglas, Ian J; Smeeth, Liam; Lees, Charlie W; Evans, Stephen JW; Goldacre, Ben; Smith, Catherine H; Langan, Sinéad M
Describing the population experiencing COVID-19 vaccine breakthrough following second vaccination in England: a cohort study from OpenSAFELY. (2022)
OpenSAFELY Collaborative; Green, Amelia; Curtis, Helen; Hulme, William; Williamson, Elizabeth; McDonald, Helen; Bhaskaran, Krishnan; Rentsch, Christopher; Schultze, Anna; MacKenna, Brian; Mahalingasivam, Viyaasan; Tomlinson, Laurie; Walker, Alex; Fisher, Louis; Massey, Jon; Andrews, Colm; Hopcroft, Lisa; Morton, Caroline; Croker, Richard; Morley, Jessica; Mehrkar, Amir; Bacon, Seb; Evans, David; Inglesby, Peter; Hickman, George; Ward, Tom; Davy, Simon; Mathur, Rohini; Tazare, John; Eggo, Rosalind; Wing, Kevin; Wong, Angel; Forbes, Harriet; Bates, Chris; Cockburn, Jonathan; Parry, John; Hester, Frank; Harper, Sam; Douglas, Ian; Evans, Stephen; Smeeth, Liam; Goldacre, Ben
Rates of serious clinical outcomes in survivors of hospitalisation with COVID-19 in England: a descriptive cohort study within the OpenSAFELY platform. (2022)
OpenSAFELY Collaborative; Tazare, John; Walker, Alex J; Tomlinson, Laurie A; Hickman, George; Rentsch, Christopher T; Williamson, Elizabeth J; Bhaskaran, Krishnan; Evans, David; Wing, Kevin; Mathur, Rohini; Wong, Angel Ys; Schultze, Anna; Bacon, Seb; Bates, Chris; Morton, Caroline E; Curtis, Helen J; Nightingale, Emily; McDonald, Helen I; Mehrkar, Amir; Inglesby, Peter; Davy, Simon; MacKenna, Brian; Cockburn, Jonathan; Hulme, William J; Warren-Gash, Charlotte; Bhate, Ketaki; Nitsch, Dorothea; Powell, Emma; Mulick, Amy; Forbes, Harriet; Minassian, Caroline; Croker, Richard; Parry, John; Hester, Frank; Harper, Sam; Eggo, Rosalind M; Evans, Stephen Jw; Smeeth, Liam; Douglas, Ian J; Goldacre, Ben
Mortality among Care Home Residents in England during the first and second waves of the COVID-19 pandemic: an observational study of 4.3 million adults over the age of 65. (2022)
Schultze, Anna; Nightingale, Emily; Evans, David; Hulme, William; Rosello, Alicia; Bates, Chris; Cockburn, Jonathan; MacKenna, Brian; Curtis, Helen J; Morton, Caroline E; Croker, Richard; Bacon, Seb; McDonald, Helen I; Rentsch, Christopher T; Bhaskaran, Krishnan; Mathur, Rohini; Tomlinson, Laurie A; Williamson, Elizabeth J; Forbes, Harriet; Tazare, John; Grint, Daniel; Walker, Alex J; Inglesby, Peter; DeVito, Nicholas J; Mehrkar, Amir; Hickman, George; Davy, Simon; Ward, Tom; Fisher, Louis; Green, Amelia Ca; Wing, Kevin; Wong, Angel Ys; McManus, Robert; Parry, John; Hester, Frank; Harper, Sam; Evans, Stephen Jw; Douglas, Ian J; Smeeth, Liam; Eggo, Rosalind M; Goldacre, Ben; Leon, David A
High-dimensional propensity scores for data-driven confounder adjustment in UK electronic health records. (2022)
Tazare, JR
Safety of COVID-19 vaccination and acute neurological events: A self-controlled case series in England using the OpenSAFELY platform. (2022)
Walker, Jemma L; Schultze, Anna; Tazare, John; Tamborska, Arina; Singh, Bhagteshwar; Donegan, Katherine; Stowe, Julia; Morton, Caroline E; Hulme, William J; Curtis, Helen J; Williamson, Elizabeth J; Mehrkar, Amir; Eggo, Rosalind M; Rentsch, Christopher T; Mathur, Rohini; Bacon, Sebastian; Walker, Alex J; Davy, Simon; Evans, David; Inglesby, Peter; Hickman, George; MacKenna, Brian; Tomlinson, Laurie; Ca Green, Amelia; Fisher, Louis; Cockburn, Jonathan; Parry, John; Hester, Frank; Harper, Sam; Bates, Christopher; Evans, Stephen Jw; Solomon, Tom; Andrews, Nick J; Douglas, Ian J; Goldacre, Ben; Smeeth, Liam; McDonald, Helen I
Association between household composition and severe COVID-19 outcomes in older people by ethnicity: an observational cohort study using the OpenSAFELY platform. (2022)
Wing, Kevin; Grint, Daniel J; Mathur, Rohini; Gibbs, Hamish P; Hickman, George; Nightingale, Emily; Schultze, Anna; Forbes, Harriet; Nafilyan, Vahé; Bhaskaran, Krishnan; Williamson, Elizabeth; House, Thomas; Pellis, Lorenzo; Herrett, Emily; Gautam, Nileesa; Curtis, Helen J; Rentsch, Christopher T; Wong, Angel YS; MacKenna, Brian; Mehrkar, Amir; Bacon, Seb; Douglas, Ian J; Evans, Stephen JW; Tomlinson, Laurie; Goldacre, Ben; Eggo, Rosalind M
Association between oral anticoagulants and COVID-19-related outcomes: a population-based cohort study. (2022)
Wong, Angel Ys; Tomlinson, Laurie; Brown, Jeremy P; Elson, William; Walker, Alex J; Schultze, Anna; Morton, Caroline E; Evans, David; Inglesby, Peter; MacKenna, Brian; Bhaskaran, Krishnan; Rentsch, Christopher T; Powell, Emma; Williamson, Elizabeth; Croker, Richard; Bacon, Seb; Hulme, William; Bates, Chris; Curtis, Helen J; Mehrkar, Amir; Cockburn, Jonathan; McDonald, Helen I; Mathur, Rohini; Wing, Kevin; Forbes, Harriet; Eggo, Rosalind M; Evans, Stephen Jw; Smeeth, Liam; Goldacre, Ben; Douglas, Ian J; (The OpenSAFELY Collaborative)
Comparative effectiveness of sotrovimab and molnupiravir for prevention of severe covid-19 outcomes in patients in the community: observational cohort study with the OpenSAFELY platform. (2022)
Zheng, Bang; Green, Amelia CA; Tazare, John; Curtis, Helen J; Fisher, Louis; Nab, Linda; Schultze, Anna; Mahalingasivam, Viyaasan; Parker, Edward PK; Hulme, William J; Bacon, Sebastian CJ; DeVito, Nicholas J; Bates, Christopher; Evans, David; Inglesby, Peter; Drysdale, Henry; Davy, Simon; Cockburn, Jonathan; Morton, Caroline E; Hickman, George; Ward, Tom; Smith, Rebecca M; Parry, John; Hester, Frank; Harper, Sam; Mehrkar, Amir; Eggo, Rosalind M; Walker, Alex J; Evans, Stephen JW; Douglas, Ian J; MacKenna, Brian; Goldacre, Ben; Tomlinson, Laurie A
Frailty and rate of fractures in patients initiating antihypertensive medications: a cohort study in primary care. (2022)
Österdahl, Marc F; Sinnott, Sarah-Jo; Douglas, Ian; Clegg, Andrew; Tomlinson, Laurie; Wong, Angel
2021
Factors associated with deaths due to COVID-19 versus other causes: population-based cohort analysis of UK primary care data and linked national death registrations within the OpenSAFELY platform. (2021)
Bhaskaran, Krishnan; Bacon, Sebastian; Evans, Stephen Jw; Bates, Chris J; Rentsch, Christopher T; MacKenna, Brian; Tomlinson, Laurie; Walker, Alex J; Schultze, Anna; Morton, Caroline E; Grint, Daniel; Mehrkar, Amir; Eggo, Rosalind M; Inglesby, Peter; Douglas, Ian J; McDonald, Helen I; Cockburn, Jonathan; Williamson, Elizabeth J; Evans, David; Curtis, Helen J; Hulme, William J; Parry, John; Hester, Frank; Harper, Sam; Spiegelhalter, David; Smeeth, Liam; Goldacre, Ben
Protocol for an observational cohort study investigating personalised medicine for intensification of treatment in people with type 2 diabetes mellitus: the PERMIT study. (2021)
Bidulka, Patrick; O'Neill, Stephen; Basu, Anirban; Wilkinson, Samantha; Silverwood, Richard J; Charlton, Paul; Briggs, Andrew; Adler, Amanda I; Khunti, Kamlesh; Tomlinson, Laurie A; Smeeth, Liam; Douglas, Ian J; Grieve, Richard
Proton pump inhibitors and risk of all-cause and cause-specific mortality: A cohort study. (2021)
Brown, Jeremy P; Tazare, John R; Williamson, Elizabeth; Mansfield, Kathryn E; Evans, Stephen J; Tomlinson, Laurie A; Bhaskaran, Krishnan; Smeeth, Liam; Wing, Kevin; Douglas, Ian J
Trends and clinical characteristics of COVID-19 vaccine recipients: a federated analysis of 57.9 million patients’ primary care records in situ using OpenSAFELY. (2021)
Curtis, Helen J; Inglesby, Peter; Morton, Caroline E; MacKenna, Brian; Green, Amelia; Hulme, William; Walker, Alex J; Morley, Jessica; Mehrkar, Amir; Bacon, Seb; Hickman, George; Bates, Chris; Croker, Richard; Evans, David; Ward, Tom; Cockburn, Jonathan; Davy, Simon; Bhaskaran, Krishnan; Schultze, Anna; Rentsch, Christopher T; Williamson, Elizabeth J; Rowan, Anna; Fisher, Louis; McDonald, Helen I; Tomlinson, Laurie; Mathur, Rohini; Drysdale, Henry; Eggo, Rosalind M; Wing, Kevin; Wong, Angel Ys; Forbes, Harriet; Parry, John; Hester, Frank; Harper, Sam; O'Hanlon, Shaun; Eavis, Alex; Jarvis, Richard; Avramov, Dima; Griffiths, Paul; Fowles, Aaron; Parkes, Nasreen; Douglas, Ian J; Evans, Stephen Jw; Smeeth, Liam; Goldacre, Ben; (The OpenSAFELY Collaborative)
OpenSAFELY NHS Service Restoration Observatory 1: primary care clinical activity in England during the first wave of COVID-19. (2021)
Curtis, Helen J; MacKenna, Brian; Croker, Richard; Inglesby, Peter; Walker, Alex J; Morley, Jessica; Mehrkar, Amir; Morton, Caroline E; Bacon, Seb; Hickman, George; Bates, Chris; Evans, David; Ward, Tom; Cockburn, Jonathan; Davy, Simon; Bhaskaran, Krishnan; Schultze, Anna; Rentsch, Christopher T; Williamson, Elizabeth J; Hulme, William J; McDonald, Helen I; Tomlinson, Laurie; Mathur, Rohini; Drysdale, Henry; Eggo, Rosalind M; Wing, Kevin; Wong, Angel Ys; Forbes, Harriet; Parry, John; Hester, Frank; Harper, Sam; Evans, Stephen Jw; Douglas, Ian J; Smeeth, Liam; Goldacre, Ben; (The OpenSAFELY Collaborative)
Association between living with children and outcomes from covid-19: OpenSAFELY cohort study of 12 million adults in England. (2021)
Forbes, Harriet; Morton, Caroline E; Bacon, Seb; McDonald, Helen I; Minassian, Caroline; Brown, Jeremy P; Rentsch, Christopher T; Mathur, Rohini; Schultze, Anna; DeVito, Nicholas J; MacKenna, Brian; Hulme, William J; Croker, Richard; Walker, Alex J; Williamson, Elizabeth J; Bates, Chris; Mehrkar, Amir; Curtis, Helen J; Evans, David; Wing, Kevin; Inglesby, Peter; Drysdale, Henry; Wong, Angel YS; Cockburn, Jonathan; McManus, Robert; Parry, John; Hester, Frank; Harper, Sam; Douglas, Ian J; Smeeth, Liam; Evans, Stephen JW; Bhaskaran, Krishnan; Eggo, Rosalind M; Goldacre, Ben; Tomlinson, Laurie A
Severity of Severe Acute Respiratory System Coronavirus 2 (SARS-CoV-2) Alpha Variant (B.1.1.7) in England. (2021)
Grint, Daniel J; Wing, Kevin; Houlihan, Catherine; Gibbs, Hamish P; Evans, Stephen JW; Williamson, Elizabeth; McDonald, Helen I; Bhaskaran, Krishnan; Evans, David; Walker, Alex J; Hickman, George; Nightingale, Emily; Schultze, Anna; Rentsch, Christopher T; Bates, Chris; Cockburn, Jonathan; Curtis, Helen J; Morton, Caroline E; Bacon, Sebastian; Davy, Simon; Wong, Angel YS; Mehrkar, Amir; Tomlinson, Laurie; Douglas, Ian J; Mathur, Rohini; MacKenna, Brian; Ingelsby, Peter; Croker, Richard; Parry, John; Hester, Frank; Harper, Sam; DeVito, Nicholas J; Hulme, Will; Tazare, John; Smeeth, Liam; Goldacre, Ben; Eggo, Rosalind M
Case fatality risk of the SARS-CoV-2 variant of concern B.1.1.7 in England, 16 November to 5 February. (2021)
Grint, Daniel J; Wing, Kevin; Williamson, Elizabeth; McDonald, Helen I; Bhaskaran, Krishnan; Evans, David; Evans, Stephen Jw; Walker, Alex J; Hickman, George; Nightingale, Emily; Schultze, Anna; Rentsch, Christopher T; Bates, Chris; Cockburn, Jonathan; Curtis, Helen J; Morton, Caroline E; Bacon, Sebastian; Davy, Simon; Wong, Angel Ys; Mehrkar, Amir; Tomlinson, Laurie; Douglas, Ian J; Mathur, Rohini; Blomquist, Paula; MacKenna, Brian; Ingelsby, Peter; Croker, Richard; Parry, John; Hester, Frank; Harper, Sam; DeVito, Nicholas J; Hulme, Will; Tazare, John; Goldacre, Ben; Smeeth, Liam; Eggo, Rosalind M
Blood cholesterol and risk of dementia in more than 1·8 million people over two decades: a retrospective cohort study. (2021)
Iwagami, Masao; Qizilbash, Nawab; Gregson, John; Douglas, Ian; Johnson, Michelle; Pearce, Neil; Evans, Stephen; Pocock, Stuart
Ethnic differences in SARS-CoV-2 infection and COVID-19-related hospitalisation, intensive care unit admission, and death in 17 million adults in England: an observational cohort study using the OpenSAFELY platform. (2021)
Mathur, Rohini; Rentsch, Christopher T; Morton, Caroline E; Hulme, William J; Schultze, Anna; MacKenna, Brian; Eggo, Rosalind M; Bhaskaran, Krishnan; Wong, Angel YS; Williamson, Elizabeth J; Forbes, Harriet; Wing, Kevin; McDonald, Helen I; Bates, Chris; Bacon, Seb; Walker, Alex J; Evans, David; Inglesby, Peter; Mehrkar, Amir; Curtis, Helen J; DeVito, Nicholas J; Croker, Richard; Drysdale, Henry; Cockburn, Jonathan; Parry, John; Hester, Frank; Harper, Sam; Douglas, Ian J; Tomlinson, Laurie; Evans, Stephen JW; Grieve, Richard; Harrison, David; Rowan, Kathy; Khunti, Kamlesh; Chaturvedi, Nishi; Smeeth, Liam; Goldacre, Ben
OpenSAFELY: impact of national guidance on switching anticoagulant therapy during COVID-19 pandemic. (2021)
OpenSAFELY Collaborative; Curtis, Helen J; MacKenna, Brian; Walker, Alex J; Croker, Richard; Mehrkar, Amir; Morton, Caroline; Bacon, Seb; Hickman, George; Inglesby, Peter; Bates, Chris; Evans, David; Ward, Tom; Cockburn, Jonathan; Davy, Simon; Bhaskaran, Krishnan; Schultze, Anna; Rentsch, Christopher T; Williamson, Elizabeth; Hulme, William; Tomlinson, Laurie; Mathur, Rohini; Drysdale, Henry; Eggo, Rosalind M; Wong, Angel Yun; Forbes, Harriet; Parry, John; Hester, Frank; Harper, Sam; Douglas, Ian; Smeeth, Liam; Goldacre, Ben
Association between warfarin and COVID-19-related outcomes compared with direct oral anticoagulants: population-based cohort study. (2021)
OpenSAFELY Collaborative; Wong, Angel YS; Tomlinson, Laurie A; Brown, Jeremy P; Elson, William; Walker, Alex J; Schultze, Anna; Morton, Caroline E; Evans, David; Inglesby, Peter; MacKenna, Brian; Bhaskaran, Krishnan; Rentsch, Christopher T; Powell, Emma; Williamson, Elizabeth; Croker, Richard; Bacon, Seb; Hulme, William; Bates, Chris; Curtis, Helen J; Mehrkar, Amir; Cockburn, Jonathan; McDonald, Helen I; Mathur, Rohini; Wing, Kevin; Forbes, Harriet; Eggo, Rosalind M; Evans, Stephen JW; Smeeth, Liam; Goldacre, Ben; Douglas, Ian J
Real-world effects of medications for stroke prevention in atrial fibrillation: protocol for a UK population-based non-interventional cohort study with validation against randomised trial results. (2021)
Powell, Emma Maud; Douglas, Ian J; Gungabissoon, Usha; Smeeth, Liam; Wing, Kevin
Unicompartmental compared with total knee replacement for patients with multimorbidities: a cohort study using propensity score stratification and inverse probability weighting. (2021)
Prats-Uribe, Albert; Kolovos, Spyros; Berencsi, Klara; Carr, Andrew; Judge, Andrew; Silman, Alan; Arden, Nigel; Petersen, Irene; Douglas, Ian J; Wilkinson, J Mark; Murray, David; Valderas, Jose M; Beard, David J; Lamb, Sarah E; Ali, M Sanni; Pinedo-Villanueva, Rafael; Strauss, Victoria Y; Prieto-Alhambra, Daniel
Early initiation of prophylactic anticoagulation for prevention of coronavirus disease 2019 mortality in patients admitted to hospital in the United States: cohort study. (2021)
Rentsch, Christopher T; Beckman, Joshua A; Tomlinson, Laurie; Gellad, Walid F; Alcorn, Charles; Kidwai-Khan, Farah; Skanderson, Melissa; Brittain, Evan; King, Joseph T; Ho, Yuk-Lam; Eden, Svetlana; Kundu, Suman; Lann, Michael F; Greevy, Robert A; Ho, P Michael; Heidenreich, Paul A; Jacobson, Daniel A; Douglas, Ian J; Tate, Janet P; Evans, Stephen JW; Atkins, David; Justice, Amy C; Freiberg, Matthew S
Hydroxychloroquine treatment does not reduce COVID-19 mortality; underdosing to the wrong patients? - Authors' reply. (2021)
Rentsch, Christopher T; DeVito, Nicholas J; MacKenna, Brian; Morton, Caroline E; Bhaskaran, Krishnan; Brown, Jeremy P; Schultze, Anna; Hulme, William J; Croker, Richard; Walker, Alex J; Williamson, Elizabeth J; Bates, Chris; Bacon, Seb; Mehrkar, Amir; Curtis, Helen J; Evans, David; Wing, Kevin; Inglesby, Peter; Mathur, Rohini; Drysdale, Henry; Wong, Angel YS; McDonald, Helen I; Cockburn, Jonathan; Forbes, Harriet; Parry, John; Hester, Frank; Harper, Sam; Smeeth, Liam; Douglas, Ian J; Dixon, William G; Evans, Stephen JW; Tomlinson, Laurie; Goldacre, Ben
description
COVID-19 and inhaled corticosteroids-another piece in an expanding puzzle. (2021)
Schultze, Anna; Douglas, Ian
Rates of serious clinical outcomes in survivors of hospitalisation with COVID-19: a descriptive cohort study within the OpenSAFELY platform. (2021)
Tazare, John; Walker, Alex J; Tomlinson, Laurie; Hickman, George; Rentsch, Christopher T; Williamson, Elizabeth J; Bhaskaran, Krishnan; Evans, David; Wing, Kevin; Mathur, Rohini; Wong, Angel YS; Schultze, Anna; Bacon, Seb; Bates, Chris; Morton, Caroline E; Curtis, Helen J; Nightingale, Emily; McDonald, Helen I; Mehrkar, Amir; Inglesby, Peter; Davy, Simon; MacKenna, Brian; Cockburn, Jonathan; Hulme, William J; Warren-Gash, Charlotte; Bhate, Ketaki; Nitsch, Dorothea; Powell, Emma; Mulick, Amy; Forbes, Harriet; Minassian, Caroline; Croker, Richard; Parry, John; Hester, Frank; Harper, Sam; Eggo, Rosalind M; Evans, Stephen JW; Smeeth, Liam; Douglas, Ian J; Goldacre, Ben
Clinical coding of long COVID in English primary care: a federated analysis of 58 million patient records in situ using OpenSAFELY. (2021)
Walker, Alex J; MacKenna, Brian; Inglesby, Peter; Tomlinson, Laurie; Rentsch, Christopher T; Curtis, Helen J; Morton, Caroline E; Morley, Jessica; Mehrkar, Amir; Bacon, Seb; Hickman, George; Bates, Chris; Croker, Richard; Evans, David; Ward, Tom; Cockburn, Jonathan; Davy, Simon; Bhaskaran, Krishnan; Schultze, Anna; Williamson, Elizabeth J; Hulme, William J; McDonald, Helen I; Mathur, Rohini; Eggo, Rosalind M; Wing, Kevin; Wong, Angel Ys; Forbes, Harriet; Tazare, John; Parry, John; Hester, Frank; Harper, Sam; O'Hanlon, Shaun; Eavis, Alex; Jarvis, Richard; Avramov, Dima; Griffiths, Paul; Fowles, Aaron; Parkes, Nasreen; Douglas, Ian J; Evans, Stephen Jw; (The OpenSAFELY Collaborative)
Changes in the rate of cardiometabolic and pulmonary events during the COVID-19 pandemic. (2021)
Walker, Alex J; Tazare, John; Hickman, George; Rentsch, Christopher T; Williamson, Elizabeth J; Bhaskaran, Krishnan; Evans, David; Wing, Kevin; Mathur, Rohini; Wong, Angel YS; Schultze, Anna; Bacon, Sebastian CJ; Bates, Chris; Morton, Caroline E; Curtis, Helen J; Nightingale, Emily; McDonald, Helen I; Mehrkar, Amir; Inglesby, Peter; MacKenna, Brian; Cockburn, Jonathan; Hulme, William J; Forbes, Harriet; Minassian, Caroline; Croker, Richard; Parry, John; Hester, Frank; Harper, Sam; Eggo, Rosalind M; Evans, Stephen JW; Smeeth, Liam; Douglas, Ian J; Tomlinson, Laurie; Goldacre, Ben
UK prevalence of underlying conditions which increase the risk of severe COVID-19 disease: a point prevalence study using electronic health records. (2021)
Walker, Jemma L; Grint, Daniel J; Strongman, Helen; Eggo, Rosalind M; Peppa, Maria; Minassian, Caroline; Mansfield, Kathryn E; Rentsch, Christopher T; Douglas, Ian J; Mathur, Rohini; Wong, Angel YS; Quint, Jennifer K; Andrews, Nick; Bernal, Jamie Lopez; Scott, J Anthony; Ramsay, Mary; Smeeth, Liam; McDonald, Helen I
OpenSAFELY: Risks of COVID-19 hospital admission and death for people with learning disabilities - a cohort study. (2021)
Williamson, Elizabeth J; McDonald, Helen I; Bhaskaran, Krishnan; Walker, Alex J; Bacon, Sebastian; Davy, Simon; Schultze, Anna; Tomlinson, Laurie; Bates, Chris; Ramsay, Mary; Curtis, Helen J; Forbes, Harriet; Wing, Kevin; Minassian, Caroline; Tazare, John; Morton, Caroline E; Nightingale, Emily; Mehrkar, Amir; Evans, Dave; Inglesby, Peter; MacKenna, Brian; Cockburn, Jonathan; Rentsch, Christopher T; Mathur, Rohini; Wong, Angel YS; Eggo, Rosalind M; Hulme, Will; Croker, Richard; Parry, John; Hester, Frank; Harper, Sam; Douglas, Ian J; Evans, Stephen JW; Smeeth, Liam; Goldacre, Ben; Kuper, Hannah
Risks of covid-19 hospital admission and death for people with learning disability: population based cohort study using the OpenSAFELY platform. (2021)
Williamson, Elizabeth J; McDonald, Helen I; Bhaskaran, Krishnan; Walker, Alex J; Bacon, Sebastian; Davy, Simon; Schultze, Anna; Tomlinson, Laurie; Bates, Chris; Ramsay, Mary; Curtis, Helen J; Forbes, Harriet; Wing, Kevin; Minassian, Caroline; Tazare, John; Morton, Caroline E; Nightingale, Emily; Mehrkar, Amir; Evans, Dave; Inglesby, Peter; MacKenna, Brian; Cockburn, Jonathan; Rentsch, Christopher T; Mathur, Rohini; Wong, Angel YS; Eggo, Rosalind M; Hulme, William; Croker, Richard; Parry, John; Hester, Frank; Harper, Sam; Douglas, Ian J; Evans, Stephen JW; Smeeth, Liam; Goldacre, Ben; Kuper, Hannah
Predicting COVID-19 related death using the OpenSAFELY platform. (2021)
Williamson, Elizabeth J; Tazare, John; Bhaskaran, Krishnan; McDonald, Helen I; Walker, Alex J; Tomlinson, Laurie; Wing, Kevin; Bacon, Sebastian; Bates, Chris; Curtis, Helen J; Forbes, Harriet; Minassian, Caroline; Morton, Caroline E; Nightingale, Emily; Mehrkar, Amir; Evans, Dave; Nicholson, Brian D; Leon, Dave; Inglesby, Peter; MacKenna, Brian; Davies, Nicholas G; DeVito, Nicholas J; Drysdale, Henry; Cockburn, Jonathan; Hulme, Will; Morley, Jess; Douglas, Ian; Rentsch, Christopher T; Mathur, Rohini; Wong, Angel; Schultze, Anna; Croker, Richard; Parry, John; Hester, Frank; Harper, Sam; Grieve, Richard; Harrison, David A; Steyerberg, Ewout W; Eggo, Rosalind M; Diaz-Ordaz, Karla; Keogh, Ruth; Evans, Stephen JW; Smeeth, Liam; Goldacre, Ben
Medications for chronic obstructive pulmonary disease: a historical non-interventional cohort study with validation against RCT results. (2021)
Wing, Kevin; Williamson, Elizabeth; Carpenter, James R; Wise, Lesley; Schneeweiss, Sebastian; Smeeth, Liam; Quint, Jennifer K; Douglas, Ian
Use of non-steroidal anti-inflammatory drugs and risk of death from COVID-19: an OpenSAFELY cohort analysis based on two cohorts. (2021)
Wong, Angel Ys; MacKenna, Brian; Morton, Caroline E; Schultze, Anna; Walker, Alex J; Bhaskaran, Krishnan; Brown, Jeremy P; Rentsch, Christopher T; Williamson, Elizabeth; Drysdale, Henry; Croker, Richard; Bacon, Seb; Hulme, William; Bates, Chris; Curtis, Helen J; Mehrkar, Amir; Evans, David; Inglesby, Peter; Cockburn, Jonathan; McDonald, Helen I; Tomlinson, Laurie; Mathur, Rohini; Wing, Kevin; Forbes, Harriet; Eggo, Rosalind M; Parry, John; Hester, Frank; Harper, Sam; Evans, Stephen Jw; Smeeth, Liam; Douglas, Ian J; Goldacre, Ben; OpenSAFELY Collaborative
2020
Comparisons of Staphylococcus aureus infection and other outcomes between users of angiotensin-converting-enzyme inhibitors and angiotensin II receptor blockers: lessons for COVID-19 from a nationwide cohort study. (2020)
Bidulka, Patrick; Iwagami, Masao; Mansfield, Kathryn E; Kalogirou, Fotini; Wong, Angel YS; Douglas, Ian J; Smeeth, Liam; Summers, Charlotte; Tomlinson, Laurie A
COVID-19 in Great Britain: epidemiological and clinical characteristics of the first few hundred (FF100) cases: a descriptive case series and case control analysis. (2020)
Boddington, Nicola L; Charlett, Andre; Elgohari, Suzanne; Walker, Jemma L; Mcdonald, Helen; Byers, Chloe; Coughlan, Laura; Garcia Vilaplana, Tatiana; Whillock, Rosie; Sinnathamby, Mary; Panagiotopoulos, Nikolaos; Letley, Louise; MacDonald, Pauline; Vivancos, Roberto; Edeghere, Obaghe; Shingleton, Joseph; Bennett, Emma; Grint, Daniel J; Strongman, Helen; Mansfield, Kathryn E; Rentsch, Christopher; Minassian, Caroline; Douglas, Ian J; Mathur, Rohini; Peppa, Maria; Cottrell, Simon; McMenamin, Jim; Zambon, Maria; Ramsay, Mary; Dabrera, Gavin; Saliba, Vanessa; Lopez Bernal, Jamie
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OpenSAFELY: impact of national guidance on switching from warfarin to direct oral anticoagulants (DOACs) in early phase of COVID-19 pandemic in England. (2020)
Curtis, Helen J; MacKenna, Brian; Walker, Alex J; Croker, Richard; Mehrkar, Amir; Morton, Caroline E; Bacon, Seb; Hickman, George; Inglesby, Peter; Bates, Chris; Evans, David; Ward, Tom; Cockburn, Jonathan; Davy, Simon; Bhaskaran, Krishnan; Schultze, Anna; Rentsch, Christopher T; Williamson, Elizabeth; Hulme, William; McDonald, Helen I; Tomlinson, Laurie; Mathur, Rohini; Drysdale, Henry; Eggo, Rosalind M; Wing, Kevin; Wong, Angel YS; Forbes, Harriet; Parry, John; Hester, Frank; Harper, Sam; Evans, Stephen JW; Douglas, Ian J; Smeeth, Liam; Goldacre, Ben
Approaches for combining primary care electronic health record data from multiple sources: a systematic review of observational studies. (2020)
Dedman, Daniel; Cabecinha, Melissa; Williams, Rachael; Evans, Stephen JW; Bhaskaran, Krishnan; Douglas, Ian J
Risk of herpes zoster after exposure to varicella to explore the exogenous boosting hypothesis: self controlled case series study using UK electronic healthcare data. (2020)
Forbes, Harriet; Douglas, Ian; Finn, Adam; Breuer, Judith; Bhaskaran, Krishnan; Smeeth, Liam; Packer, Simon; Langan, Sinéad M; Mansfield, Kathryn E; Marlow, Robin; Whitaker, Heather; Warren-Gash, Charlotte
Association between living with children and outcomes from COVID-19: an OpenSAFELY cohort study of 12 million adults in England. (2020)
Forbes, Harriet; Morton, Caroline E; Bacon, Seb; McDonald, Helen I; Minassian, Caroline; Brown, Jeremy P; Rentsch, Christopher T; Mathur, Rohini; Schultze, Anna; DeVito, Nicholas J; MacKenna, Brian; Hulme, William J; Croker, Richard; Walker, Alex J; Williamson, Elizabeth J; Bates, Chris; Mehrkar, Amir; Curtis, Helen J; Evans, David; Wing, Kevin; Inglesby, Peter; Drysdale, Henry; Wong, Angel YS; Cockburn, Jonathan; McManus, Robert; Parry, John; Hester, Frank; Harper, Sam; Douglas, Ian J; Smeeth, Liam; Evans, Stephen JW; Bhaskaran, Krishnan; Eggo, Rosalind M; Goldacre, Ben; Tomlinson, Laurie A
Ethnic disparities in initiation and intensification of diabetes treatment in adults with type 2 diabetes in the UK, 1990-2017: A cohort study. (2020)
Mathur, Rohini; Farmer, Ruth E; Eastwood, Sophie V; Chaturvedi, Nish; Douglas, Ian; Smeeth, Liam
Ethnic differences in SARS-CoV-2 infection and COVID-19-related hospitalisation, intensive care unit admission, and death in 17 million adults in England: an observational cohort study using the OpenSAFELY platform. (2020)
Mathur, Rohini; Rentsch, Christopher T; Morton, Caroline E; Hulme, William J; Schultze, Anna; MacKenna, Brian; Eggo, Rosalind M; Bhaskaran, Krishnan; Wong, Angel YS; Williamson, Elizabeth J; Forbes, Harriet; Wing, Kevin; McDonald, Helen I; Bates, Chris; Bacon, Seb; Walker, Alex J; Evans, David; Inglesby, Peter; Mehrkar, Amir; Curtis, Helen J; DeVito, Nicholas J; Croker, Richard; Drysdale, Henry; Cockburn, Jonathan; Parry, John; Hester, Frank; Harper, Sam; Douglas, Ian J; Tomlinson, Laurie; Evans, Stephen JW; Grieve, Richard; Harrison, David; Rowan, Kathy; Khunti, Kamlesh; Chaturvedi, Nishi; Smeeth, Liam; Goldacre, Ben; OpenSAFELY Collaborative
Early initiation of prophylactic anticoagulation for prevention of COVID-19 mortality: a nationwide cohort study of hospitalized patients in the United States. (2020)
Rentsch, Christopher T; Beckman, Joshua A; Tomlinson, Laurie; Gellad, Walid F; Alcorn, Charles; Kidwai-Khan, Farah; Skanderson, Melissa; Brittain, Evan; King, Joseph T; Ho, Yuk-Lam; Eden, Svetlana; Kundu, Suman; Lann, Michael F; Greevy, Robert A; Ho, P Michael; Heidenreich, Paul A; Jacobson, Daniel A; Douglas, Ian J; Tate, Janet P; Evans, Stephen Jw; Atkins, David; Justice, Amy C; Freiberg, Matthew S
Effect of pre-exposure use of hydroxychloroquine on COVID-19 mortality: a population-based cohort study in patients with rheumatoid arthritis or systemic lupus erythematosus using the OpenSAFELY platform. (2020)
Rentsch, Christopher T; DeVito, Nicholas J; MacKenna, Brian; Morton, Caroline E; Bhaskaran, Krishnan; Brown, Jeremy P; Schultze, Anna; Hulme, William J; Croker, Richard; Walker, Alex J; Williamson, Elizabeth J; Bates, Chris; Bacon, Seb; Mehrkar, Amir; Curtis, Helen J; Evans, David; Wing, Kevin; Inglesby, Peter; Mathur, Rohini; Drysdale, Henry; Wong, Angel YS; McDonald, Helen I; Cockburn, Jonathan; Forbes, Harriet; Parry, John; Hester, Frank; Harper, Sam; Smeeth, Liam; Douglas, Ian J; Dixon, William G; Evans, Stephen JW; Tomlinson, Laurie; Goldacre, Ben
Hydroxychloroquine for prevention of COVID-19 mortality: a population-based cohort study. (2020)
Rentsch, Christopher T; DeVito, Nicholas J; MacKenna, Brian; Morton, Caroline E; Bhaskaran, Krishnan; Brown, Jeremy P; Schultze, Anna; Hulme, William J; Croker, Richard; Walker, Alex J; Williamson, Elizabeth J; Bates, Chris; Bacon, Seb; Mehrkar, Amir; Curtis, Helen J; Evans, David; Wing, Kevin; Inglesby, Peter; Mathur, Rohini; Drysdale, Henry; Wong, Angel YS; McDonald, Helen I; Cockburn, Jonathan; Forbes, Harriet; Parry, John; Hester, Frank; Harper, Sam; Smeeth, Liam; Douglas, Ian J; Dixon, William G; Evans, Stephen JW; Tomlinson, Laurie; Goldacre, Ben
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Impact of pre-exposure time bias in self-controlled case series when the event conditions the exposure: Hip/femur fracture and use of benzodiazepines as a case study. (2019)
Requena, Gema; Douglas, Ian J; Huerta, Consuelo; de Abajo, Francisco
Inhaled corticosteroid use and risk COVID-19 related death among 966,461 patients with COPD or asthma: an OpenSAFELY analysis. (2020)
Schultze, Anna; Walker, Alex J; MacKenna, Brian; Morton, Caroline E; Bhaskaran, Krishnan; Brown, Jeremy P; Rentsch, Christopher T; Williamson, Elizabeth; Drysdale, Henry; Croker, Richard; Bacon, Seb; Hulme, William; Bates, Chris; Curtis, Helen J; Mehrkar, Amir; Evans, David; Inglesby, Peter; Cockburn, Jonathan; McDonald, Helen I; Tomlinson, Laurie; Mathur, Rohini; Wing, Kevin; Wong, Angel YS; Forbes, Harriet; Parry, John; Hester, Frank; Harper, Sam; Evans, Stephen JW; Quint, Jennifer; Smeeth, Liam; Douglas, Ian J; Goldacre, Ben
Risk of COVID-19-related death among patients with chronic obstructive pulmonary disease or asthma prescribed inhaled corticosteroids: an observational cohort study using the OpenSAFELY platform. (2020)
Schultze, Anna; Walker, Alex J; MacKenna, Brian; Morton, Caroline E; Bhaskaran, Krishnan; Brown, Jeremy P; Rentsch, Christopher T; Williamson, Elizabeth; Drysdale, Henry; Croker, Richard; Bacon, Seb; Hulme, William; Bates, Chris; Curtis, Helen J; Mehrkar, Amir; Evans, David; Inglesby, Peter; Cockburn, Jonathan; McDonald, Helen I; Tomlinson, Laurie; Mathur, Rohini; Wing, Kevin; Wong, Angel YS; Forbes, Harriet; Parry, John; Hester, Frank; Harper, Sam; Evans, Stephen JW; Quint, Jennifer; Smeeth, Liam; Douglas, Ian J; Goldacre, Ben; OpenSAFELY Collaborative
First line drug treatment for hypertension and reductions in blood pressure according to age and ethnicity: cohort study in UK primary care. (2020)
Sinnott, Sarah-Jo; Douglas, Ian J; Smeeth, Liam; Williamson, Elizabeth; Tomlinson, Laurie A
Implementing high-dimensional propensity score principles to improve confounder adjustment in UK electronic health records. (2020)
Tazare, John; Smeeth, Liam; Evans, Stephen JW; Williamson, Elizabeth; Douglas, Ian J
Transparency of high-dimensional propensity score analyses: Guidance for diagnostics and reporting. (2020)
Tazare, John; Wyss, Richard; Franklin, Jessica M; Smeeth, Liam; Evans, Stephen JW; Wang, Shirley V; Schneeweiss, Sebastian; Douglas, Ian J; Williamson, Elizabeth; Gagne, Joshua J
Risk of neuropsychiatric and cardiovascular adverse events following treatment with varenicline and nicotine replacement therapy in the UK Clinical Practice Research Datalink: a case-cross-over study. (2020)
Thomas, Kyla H; Davies, Neil M; Taylor, Amy E; Taylor, Gemma MJ; Gunnell, David; Martin, Richard M; Douglas, Ian
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UK prevalence of underlying conditions which increase the risk of severe COVID-19 disease: a point prevalence study using electronic health records. (2020)
Walker, Jemma L; Grint, Daniel J; Strongman, Helen; Eggo, Rosalind M; Peppa, Maria; Minassian, Caroline; Mansfield, Kathryn E; Rentsch, Christopher T; Douglas, Ian J; Mathur, Rohini; Wong, Angel YS; Quint, Jennifer K; Andrews, Nick; Bernal, Jamie Lopez; Scott, J Anthony; Ramsay, Mary; Smeeth, Liam; McDonald, Helen
Comparative effects of sulphonylureas, dipeptidyl peptidase-4 inhibitors and sodium-glucose co-transporter-2 inhibitors added to metformin monotherapy: a propensity-score matched cohort study in UK primary care. (2020)
Wilkinson, Samantha; Williamson, Elizabeth; Pokrajac, Ana; Fogarty, Damian; Stirnadel-Farrant, Heide; Smeeth, Liam; Douglas, Ian J; Tomlinson, Laurie A
Study protocol: Comparison of different risk prediction modelling approaches for COVID-19 related death using the OpenSAFELY platform. (2020)
Williamson, Elizabeth J; Tazare, John; Bhaskaran, Krishnan; Walker, Alex J; McDonald, Helen I; Tomlinson, Laurie A; Bacon, Sebastian; Bates, Chris; Curtis, Helen J; Forbes, Harriet; Minassian, Caroline; Morton, Caroline E; Nightingale, Emily; Mehrkar, Amir; Evans, Dave; Nicholson, Brian D; Leon, David; Inglesby, Peter; MacKenna, Brian; Cockburn, Jonathan; Davies, Nicholas G; Hulme, Will J; Morley, Jessica; Douglas, Ian J; Rentsch, Christopher T; Mathur, Rohini; Wong, Angel; Schultze, Anna; Croker, Richard; Parry, John; Hester, Frank; Harper, Sam; Perera, Rafael; Grieve, Richard; Harrison, David; Steyerberg, Ewout; Eggo, Rosalind M; Diaz-Ordaz, Karla; Keogh, Ruth; Evans, Stephen JW; Smeeth, Liam; Goldacre, Ben
Factors associated with COVID-19-related death using OpenSAFELY. (2020)
Williamson, Elizabeth J; Walker, Alex J; Bhaskaran, Krishnan; Bacon, Seb; Bates, Chris; Morton, Caroline E; Curtis, Helen J; Mehrkar, Amir; Evans, David; Inglesby, Peter; Cockburn, Jonathan; McDonald, Helen I; MacKenna, Brian; Tomlinson, Laurie; Douglas, Ian J; Rentsch, Christopher T; Mathur, Rohini; Wong, Angel YS; Grieve, Richard; Harrison, David; Forbes, Harriet; Schultze, Anna; Croker, Richard; Parry, John; Hester, Frank; Harper, Sam; Perera, Rafael; Evans, Stephen JW; Smeeth, Liam; Goldacre, Ben
OpenSAFELY: factors associated with COVID-19-related hospital death in the linked electronic health records of 17 million adult NHS patients. (2020)
Williamson, Elizabeth; Walker, Alex J; Bhaskaran, Krishnan; Bacon, Seb; Bates, Chris; Morton, Caroline E; Curtis, Helen J; Mehrkar, Amir; Evans, David; Inglesby, Peter; Cockburn, Jonathan; McDonald, Helen I; MacKenna, Brian; Tomlinson, Laurie; Douglas, Ian J; Rentsch, Christopher T; Mathur, Rohini; Wong, Angel; Grieve, Richard; Harrison, David; Forbes, Harriet; Schultze, Anna; Croker, Richard; Parry, John; Hester, Frank; Harper, Sam; Perera, Raf; Evans, Stephen; Smeeth, Liam; Goldacre, Ben
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Real world effects of COPD medications: a cohort study with validation against results from randomised controlled trials. (2020)
Wing, Kevin; Williamson, Elizabeth; Carpenter, James R; Wise, Lesley; Schneeweiss, Sebastian; Smeeth, Liam; Quint, Jennifer K; Douglas, Ian
OpenSAFELY: Do adults prescribed non-steroidal anti-inflammatory drugs have an increased risk of death from COVID-19? (2020)
Wong, Angel YS; MacKenna, Brian; Morton, Caroline E; Schultze, Anna; Walker, Alex J; Bhaskaran, Krishnan; Brown, Jeremy P; Rentsch, Christopher T; Williamson, Elizabeth; Drysdale, Henry; Croker, Richard; Bacon, Seb; Hulme, William; Bates, Chris; Curtis, Helen J; Mehrkar, Amir; Evans, David; Inglesby, Peter; Cockburn, Jonathan; McDonald, Helen I; Tomlinson, Laurie; Mathur, Rohini; Wing, Kevin; Forbes, Harriet; Parry, John; Hester, Frank; Harper, Sam; Evans, Stephen JW; Smeeth, Liam; Douglas, Ian J; Goldacre, Ben
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2019
Cost saving of switching to equivalent inhalers and its effect on health outcomes. (2019)
Bloom, Chloe I; Douglas, Ian; Olney, Jack; D'Ancona, Grainne; Smeeth, Liam; Quint, Jennifer K
Use of real-world evidence in postmarketing medicines regulation in the European Union: a systematic assessment of European Medicines Agency referrals 2013-2017. (2019)
Brown, Jeremy Philip; Wing, Kevin; Evans, Stephen J; Bhaskaran, Krishnan; Smeeth, Liam; Douglas, Ian J
Blood pressure and risk of dementia and its subtypes: a historical cohort study with long-term follow-up in 2.6 million people. (2019)
Gregson, J; Qizilbash, N; Iwagami, M; Douglas, I; Johnson, M; Pearce, N; Pocock, S
description
Thromboembolic, bleeding, and mortality risks among patients with nonvalvular atrial fibrillation treated with dual antiplatelet therapy versus oral anticoagulants: A population-based study. (2019)
Lau, Wallis CY; Douglas, Ian J; Wong, Ian CK; Smeeth, Liam; Lip, Gregory YH; Leung, Wai K; Siu, Chung-Wah; Cheung, Bernard MY; Mok, Michael TC; Chan, Esther W
Asthma in electronic health records: validity and phenotyping. (2019)
Nissen, FW
Clinical profile of predefined asthma phenotypes in a large cohort of UK primary care patients (Clinical Practice Research Datalink). (2019)
Nissen, Francis; Douglas, Ian J; Müllerová, Hana; Pearce, Neil; Bloom, Chloe I; Smeeth, Liam; Quint, Jennifer K
How to validate a diagnosis recorded in electronic health records. (2018)
Nissen, Francis; Quint, Jennifer K; Morales, Daniel R; Douglas, Ian J
Association of Relative Age in the School Year With Diagnosis of Intellectual Disability, Attention-Deficit/Hyperactivity Disorder, and Depression. (2019)
Root, Adrian; Brown, Jeremy P; Forbes, Harriet J; Bhaskaran, Krishnan; Hayes, Joseph; Smeeth, Liam; Douglas, Ian J
The comparative effectiveness of fourth-line drugs in resistant hypertension: An application in electronic health record data. (2019)
Sinnott, Sarah-Jo; Smeeth, Liam; Williamson, Elizabeth; Perel, Pablo; Nitsch, Dorothea; Tomlinson, Laurie A; Douglas, Ian J
2018
Association of BMI with overall and cause-specific mortality: a population-based cohort study of 3·6 million adults in the UK. (2018)
Bhaskaran, Krishnan; Dos-Santos-Silva, Isabel; Leon, David A; Douglas, Ian J; Smeeth, Liam
Trimethoprim use for urinary tract infection and risk of adverse outcomes in older patients: cohort study. (2018)
Crellin, Elizabeth; Mansfield, Kathryn E; Leyrat, Clémence; Nitsch, Dorothea; Douglas, Ian J; Root, Adrian; Williamson, Elizabeth; Smeeth, Liam; Tomlinson, Laurie A
Gastrointestinal bleeding risk of selective serotonin reuptake inhibitors by level of kidney function: A population-based cohort study. (2018)
Iwagami, Masao; Tomlinson, Laurie A; Mansfield, Kathryn E; Douglas, Ian J; Smeeth, Liam; Nitsch, Dorothea
Long-term effects of bariatric surgery on acute kidney injury: a propensity-matched cohort in the UK Clinical Practice Research Datalink. (2018)
Koppe, Uwe; Nitsch, Dorothea; Mansfield, Kathryn E; Mathur, Rohini; Bhaskaran, Krishnan; Batterham, Rachel L; Smeeth, Liam; Douglas, Ian J
Acute kidney injury and infections in patients taking antihypertensive drugs: a self-controlled case series analysis. (2018)
Mansfield, Kathryn E; Douglas, Ian J; Nitsch, Dorothea; Thomas, Sara L; Smeeth, Liam; Tomlinson, Laurie A
Concomitant diagnosis of asthma and COPD: a quantitative study in UK primary care. (2018)
Nissen, Francis; Morales, Daniel R; Mullerova, Hana; Smeeth, Liam; Douglas, Ian J; Quint, Jennifer K
Myocardial Infarction and Ischemic Stroke after Exacerbations of Chronic Obstructive Pulmonary Disease. (2018)
Rothnie, Kieran J; Connell, Olivia; Müllerová, Hana; Smeeth, Liam; Pearce, Neil; Douglas, Ian; Quint, Jennifer K
A systematic review comparing the evidence for kidney function outcomes between oral antidiabetic drugs for type 2 diabetes. (2018)
Wilkinson, Samantha V; Tomlinson, Laurie A; Iwagami, Masao; Stirnadel-Farrant, Heide A; Smeeth, Liam; Douglas, Ian
Factors associated with choice of intensification treatment for type 2 diabetes after metformin monotherapy: a cohort study in UK primary care. (2018)
Wilkinson, Samantha; Douglas, Ian J; Williamson, Elizabeth; Stirnadel-Farrant, Heide A; Fogarty, Damian; Pokrajac, Ana; Smeeth, Liam; Tomlinson, Laurie A
Changing use of antidiabetic drugs in the UK: trends in prescribing 2000-2017. (2018)
Wilkinson, Samantha; Douglas, Ian; Stirnadel-Farrant, Heide; Fogarty, Damian; Pokrajac, Ana; Smeeth, Liam; Tomlinson, Laurie
Real-world effects of medications for chronic obstructive pulmonary disease: protocol for a UK population-based non-interventional cohort study with validation against randomised trial results. (2018)
Wing, Kevin; Williamson, Elizabeth; Carpenter, James R; Wise, Lesley; Schneeweiss, Sebastian; Smeeth, Liam; Quint, Jennifer K; Douglas, Ian
Signal Detection for Recently Approved Products: Adapting and Evaluating Self-Controlled Case Series Method Using a US Claims and UK Electronic Medical Records Database. (2017)
Zhou, Xiaofeng; Douglas, Ian J; Shen, Rongjun; Bate, Andrew
2017
Exacerbation risk and characterisation of the UK's asthma population from infants to old age. (2017)
Bloom, Chloe I; Nissen, Francis; Douglas, Ian J; Smeeth, Liam; Cullinan, Paul; Quint, Jennifer K
Self-controlled case series with multiple event types. (2016)
Ghebremichael-Weldeselassie, Yonas; Whitaker, Heather J; Douglas, Ian J; Smeeth, Liam; Farrington, C Paddy
Propensity score analysis with partially observed covariates: How should multiple imputation be used? (2017)
Leyrat, C; Seaman, SR; White, IR; Douglas, I; Smeeth, L; Kim, J; Resche-Rigon, M; Carpenter, JR; Williamson, EJ
Population trends in the 10-year incidence and prevalence of diabetic retinopathy in the UK: a cohort study in the Clinical Practice Research Datalink 2004-2014. (2017)
Mathur, Rohini; Bhaskaran, Krishnan; Edwards, Emma; Lee, Helen; Chaturvedi, Nishi; Smeeth, Liam; Douglas, Ian
Cardiovascular Outcomes after a Respiratory Tract Infection among Adults with Non-Cystic Fibrosis Bronchiectasis: A General Population-based Study. (2017)
Navaratnam, Vidya; Root, Adrian A; Douglas, Ian; Smeeth, Liam; Hubbard, Richard B; Quint, Jennifer K
Validation of asthma recording in the Clinical Practice Research Datalink (CPRD). (2017)
Nissen, Francis; Morales, Daniel R; Mullerova, Hana; Smeeth, Liam; Douglas, Ian J; Quint, Jennifer K
Validation of asthma recording in electronic health records: protocol for a systematic review. (2017)
Nissen, Francis; Quint, Jennifer K; Wilkinson, Samantha; Mullerova, Hana; Smeeth, Liam; Douglas, Ian J
Validation of asthma recording in electronic health records: a systematic review. (2017)
Nissen, Francis; Quint, Jennifer K; Wilkinson, Samantha; Mullerova, Hana; Smeeth, Liam; Douglas, Ian J
Re: Biomedical Informatics Approaches to Identifying Drug-Drug Interactions: Application to Insulin Secretagogues. (2017)
Root, Adrian; Douglas, Ian; Evans, Stephen
Trends for prevalence and incidence of resistant hypertension: population based cohort study in the UK 1995-2015. (2017)
Sinnott, Sarah-Jo; Smeeth, Liam; Williamson, Elizabeth; Douglas, Ian J
Pharmacoepidemiology for nephrologists: do proton pump inhibitors cause chronic kidney disease? (2016)
Tomlinson, Laurie A; Fogarty, Damian G; Douglas, Ian; Nitsch, Dorothea
Reporting to Improve Reproducibility and Facilitate Validity Assessment for Healthcare Database Studies V1.0. (2017)
Wang, Shirley V; Schneeweiss, Sebastian; Berger, Marc L; Brown, Jeffrey; de Vries, Frank; Douglas, Ian; Gagne, Joshua J; Gini, Rosa; Klungel, Olaf; Mullins, C Daniel; Nguyen, Michael D; Rassen, Jeremy A; Smeeth, Liam; Sturkenboom, Miriam; joint ISPE-ISPOR Special Task Force on Real World Evidence in He
Reporting to Improve Reproducibility and Facilitate Validity Assessment for Healthcare Database Studies V1.0. (2017)
Wang, Shirley V; Schneeweiss, Sebastian; Berger, Marc L; Brown, Jeffrey; de Vries, Frank; Douglas, Ian; Gagne, Joshua J; Gini, Rosa; Klungel, Olaf; Mullins, C Daniel; Nguyen, Michael D; Rassen, Jeremy A; Smeeth, Liam; Sturkenboom, Miriam; joint ISPE‐ISPOR Special Task Force on Real World Evidence in He
Investigating the assumptions of the self-controlled case series method. (2017)
Whitaker, Heather J; Ghebremichael-Weldeselassie, Yonas; Douglas, Ian J; Smeeth, Liam; Farrington, C Paddy
Quantification of the risk of liver injury associated with flucloxacillin: a UK population-based cohort study. (2017)
Wing, Kevin; Bhaskaran, Krishnan; Pealing, Louise; Root, Adrian; Smeeth, Liam; van Staa, Tjeerd P; Klungel, Olaf H; Reynolds, Robert F; Douglas, Ian
Lansoprazole use and tuberculosis incidence in the United Kingdom Clinical Practice Research Datalink: A population based cohort. (2017)
Yates, Tom A; Tomlinson, Laurie A; Bhaskaran, Krishnan; Langan, Sinead; Thomas, Sara; Smeeth, Liam; Douglas, Ian J
2016
Latest trends in ADHD drug prescribing patterns in children in the UK: prevalence, incidence and persistence. (2016)
Beau-Lejdstrom, Raphaelle; Douglas, Ian; Evans, Stephen JW; Smeeth, Liam
Association between oral fluoroquinolones and seizures: A self-controlled case series study. (2016)
Chui, Celine SL; Chan, Esther W; Wong, Angel YS; Root, Adrian; Douglas, Ian J; Wong, Ian CK
description
Oral Fluoroquinolone Use and Retinal Detachment. (2016)
Douglas, Ian J; Root, Adrian; Krishnan, Bhaskaran
Phosphodiesterase Type 5 Inhibitors and Risk of Malignant Melanoma: Matched Cohort Study Using Primary Care Data from the UK Clinical Practice Research Datalink. (2016)
Matthews, Anthony; Langan, Sinéad M; Douglas, Ian J; Smeeth, Liam; Bhaskaran, Krishnan
Self controlled case series methods: an alternative to standard epidemiological study designs. (2016)
Petersen, Irene; Douglas, Ian; Whitaker, Heather
The Prevalence of Huntington's Disease. (2016)
Rawlins, Michael D; Wexler, Nancy S; Wexler, Alice R; Tabrizi, Sarah J; Douglas, Ian; Evans, Stephen JW; Smeeth, Liam
description
Methodological issues in electronic healthcare database studies of drug cancer associations: identification of cancer, and drivers of
discrepant results. (2016)
Rañopa, ME
Evaluation of the risk of cardiovascular events with clarithromycin using both propensity score and self-controlled study designs. (2016)
Root, AA; Wong, AY; Ghebremichael-Weldeselassie, Y; Smeeth, L; Bhaskaran, K; Evans, SJ; Brauer, R; Wong, IC; Navaratnam, V; Douglas, I
OS 04-07 THE COMPARATIVE EFFECTIVENESS OF 4TH LINE ANTI-HYPERTENSIVE AGENTS IN PATIENTS WITH RESISTANT HYPERTENSION: A META-ANALYSIS. (2016)
Sinnott, SJ; Root, A; Mathur, R; Mansfield, K; Tomlinson, L; Douglas, I
OS 04-07 THE COMPARATIVE EFFECTIVENESS OF 4TH LINE ANTI-HYPERTENSIVE AGENTS IN PATIENTS WITH RESISTANT HYPERTENSION: A META-ANALYSIS. (2016)
Sinnott, SJ; Root, A; Mathur, R; Mansfield, K; Tomlinson, L; Douglas, I
Comparative effectiveness of fourth-line anti-hypertensive agents in resistant hypertension: A systematic review and meta-analysis. (2016)
Sinnott, SJ; Tomlinson, LA; Root, AA; Mathur, R; Mansfield, KE; Smeeth, L; Douglas, IJ
Incidence of adult Huntington's disease in the UK: a UK-based primary care study and a systematic review. (2016)
Wexler, Nancy S; Collett, Laura; Wexler, Alice R; Rawlins, Michael D; Tabrizi, Sarah J; Douglas, Ian; Smeeth, Liam; Evans, Stephen J
Improving the measurement and detection of serious adverse
drug reactions in databases of stored electronic health records. (2016)
Wing, Kevin
Optimising case detection within UK electronic health records: use of multiple linked databases for detecting liver injury. (2016)
Wing, Kevin; Bhaskaran, Krishnan; Smeeth, Liam; van Staa, Tjeerd P; Klungel, Olaf H; Reynolds, Robert F; Douglas, Ian
Cardiovascular outcomes associated with use of clarithromycin: population based study. (2016)
Wong, Angel YS; Root, Adrian; Douglas, Ian J; Chui, Celine SL; Chan, Esther W; Ghebremichael-Weldeselassie, Yonas; Siu, Chung-Wah; Smeeth, Liam; Wong, Ian CK
Case-only designs for studying the association of antidepressants and hip or femur fracture. (2016)
de Groot, MC; Candore, G; Uddin, MJ; Souverein, PC; Ali, MS; Belitser, SV; Huerta, C; Groenwold, RH; Alvarez, Y; Slattery, J; Korevaar, J; Hoes, AW; Roes, KC; de Boer, A; Douglas, IJ; Schlienger, RG; Reynolds, R; Klungel, OH; Gardarsdottir, H
2015
Glitazone Treatment and Incidence of Parkinson's Disease among People with Diabetes: A Retrospective Cohort Study. (2015)
Brauer, Ruth; Bhaskaran, Krishnan; Chaturvedi, Nishi; Dexter, David T; Smeeth, Liam; Douglas, Ian
Risk of acute liver injury associated with use of antibiotics. Comparative cohort and nested case-control studies using two primary care databases in Europe. (2015)
Brauer, Ruth; Douglas, Ian; Garcia Rodriguez, Luis Alberto; Downey, Gerald; Huerta, Consuelo; de Abajo, Francisco; Bate, Andrew; Feudjo Tepie, Maurille; de Groot, Mark CH; Schlienger, Raymond; Reynolds, Robert; Smeeth, Liam; Klungel, Olaf; Ruigómez, Ana
Prevalence of antibiotic use: a comparison across various European health care data sources. (2015)
Brauer, Ruth; Ruigómez, Ana; Downey, Gerry; Bate, Andrew; Garcia Rodriguez, Luis Alberto; Huerta, Consuelo; Gil, Miguel; de Abajo, Francisco; Requena, Gema; Alvarez, Yolanda; Slattery, Jim; de Groot, Mark; Souverein, Patrick; Hesse, Ulrik; Rottenkolber, Marietta; Schmiedl, Sven; de Vries, Frank; Tepie, Maurille Feudjo; Schlienger, Raymond; Smeeth, Liam; Douglas, Ian; Reynolds, Robert; Klungel, Olaf
The risk of acute liver injury among users of antibiotic medications: a comparison of case-only studies. (2015)
Brauer, Ruth; Ruigómez, Ana; Klungel, Olaf; Reynolds, Robert; Feudjo Tepie, Maurille; Smeeth, Liam; Douglas, Ian
The effectiveness of pharmaceutical interventions for obesity: weight loss with orlistat and sibutramine in a United Kingdom population-based cohort. (2015)
Douglas, Ian J; Bhaskaran, Krishnan; Batterham, Rachel L; Smeeth, Liam
Bariatric Surgery in the United Kingdom: A Cohort Study of Weight Loss and Clinical Outcomes in Routine Clinical Care. (2015)
Douglas, Ian J; Bhaskaran, Krishnan; Batterham, Rachel L; Smeeth, Liam
The effect of sibutramine prescribing in routine clinical practice on cardiovascular outcomes: a cohort study in the United Kingdom. (2015)
Hayes, JF; Bhaskaran, K; Batterham, R; Smeeth, L; Douglas, I
description
Herpes zoster, acute cardiovascular events and the role of zoster vaccination. (2015)
Minassian, C; Thomas, S; Smeeth, L; Douglas, I; Brauer, R; Langan, S
Acute Cardiovascular Events after Herpes Zoster: A Self-Controlled Case Series Analysis in Vaccinated and Unvaccinated Older Residents of the United States. (2015)
Minassian, Caroline; Thomas, Sara L; Smeeth, Liam; Douglas, Ian; Brauer, Ruth; Langan, Sinéad M
BMI and risk of dementia in two million people over two decades: a retrospective cohort study. (2015)
Qizilbash, Nawab; Gregson, John; Johnson, Michelle E; Pearce, Neil; Douglas, Ian; Wing, Kevin; Evans, Stephen JW; Pocock, Stuart J
Do case-only designs yield consistent results across design and different databases? A case study of hip fractures and benzodiazepines. (2015)
Requena, Gema; Logie, John; Martin, Elisa; Boudiaf, Nada; González González, Rocío; Huerta, Consuelo; Alvarez, Arturo; Webb, David; Bate, Andrew; García Rodríguez, Luis A; Reynolds, Robert; Schlienger, Raymond; Gardarsdottir, Helga; de Groot, Mark; Klungel, Olaf H; de Abajo, Fancisco; Douglas, Ian J
Risk of pancreatic cancer associated with use of incretin-based therapy and other glucose-lowering agents: a nationwide case-control study in Denmark. (2015)
Thomsen, RW; Christensen, DH; Kahlert, J; Knudsen, ST; Pedersen, L; Norrelund, H; Dekkers, OM; Douglas, I; Marchesini, G; Smeeth, L; Moller, N; Beck-Nielsen, H; Jorgensen, JO; Sorensen, HT
2014
Body-mass index and risk of 22 specific cancers: a population-based cohort study of 5·24 million UK adults. (2014)
Bhaskaran, Krishnan; Douglas, Ian; Forbes, Harriet; dos-Santos-Silva, Isabel; Leon, David A; Smeeth, Liam
Antipsychotic drugs and risks of myocardial infarction: a self-controlled case series study. (2014)
Brauer, Ruth; Smeeth, Liam; Anaya-Izquierdo, Karim; Timmis, Adam; Denaxas, Spiros C; Farrington, C Paddy; Whitaker, Heather; Hemingway, Harry; Douglas, Ian
Angiotensin receptor blockers and risk of dementia: cohort study in UK Clinical Practice Research Datalink. (2014)
Goh, Kah L; Bhaskaran, Krishnan; Minassian, Caroline; Evans, Stephen JW; Smeeth, Liam; Douglas, Ian J
Statins and the risk of type 2 diabetes mellitus: cohort study using the UK clinical practice pesearch datalink. (2014)
Macedo, Ana Filipa; Douglas, Ian; Smeeth, Liam; Forbes, Harriet; Ebrahim, Shah
Methylphenidate and the risk of trauma. (2014)
Man, Kenneth KC; Chan, Esther W; Coghill, David; Douglas, Ian; Ip, Patrick; Leung, Ling-Pong; Tsui, Matthew SH; Wong, Wilfred HS; Wong, Ian CK
Red blood cell transfusion and mortality in trauma patients: risk-stratified analysis of an observational study. (2014)
Perel, Pablo; Clayton, Tim; Altman, Doug G; Croft, Peter; Douglas, Ian; Hemingway, Harry; Hingorani, Aroon; Morley, Katherine I; Riley, Richard; Timmis, Adam; Van der Windt, Danielle; Roberts, Ian; PROGRESS Partnership
The identification of incident cancers in UK primary care databases: a systematic review. (2014)
Rañopa, Michael; Douglas, Ian; van Staa, Tjeerd; Smeeth, Liam; Klungel, Olaf; Reynolds, Robert; Bhaskaran, Krishnan
2013
Representativeness and optimal use of body mass index (BMI) in the UK Clinical Practice Research Datalink (CPRD). (2013)
Bhaskaran, Krishnan; Forbes, Harriet J; Douglas, Ian; Leon, David A; Smeeth, Liam
Orlistat and the risk of acute liver injury: self controlled case series study in UK Clinical Practice Research Datalink. (2013)
Douglas, Ian J; Langham, Julia; Bhaskaran, Krishnan; Brauer, Ruth; Smeeth, Liam
Juvenile Huntington's disease: a population-based study using the General Practice Research Database. (2013)
Douglas, Ian; Evans, Stephen; Rawlins, Michael D; Smeeth, Liam; Tabrizi, Sarah J; Wexler, Nancy S
Prevalence of adult Huntington's disease in the UK based on diagnoses recorded in general practice records. (2013)
Evans, Stephen JW; Douglas, Ian; Rawlins, Michael D; Wexler, Nancy S; Tabrizi, Sarah J; Smeeth, Liam
The association between Parkinson's disease and anti-epilepsy drug carbamazepine: a case-control study using the UK General Practice Research Database. (2013)
Skow, Aine; Douglas, Ian; Smeeth, Liam
Development of predictive genetic tests for improving the safety of new medicines: the utilization of routinely collected electronic health records. (2013)
Wing, Kevin; Douglas, Ian; Bhaskaran, Krishnan; Klungel, Olaf H; Reynolds, Robert F; Pirmohamed, Munir; Smeeth, Liam; van Staa, Tjeerd P
2012
Angiotensin receptor blockers and risk of cancer: cohort study among people receiving antihypertensive drugs in UK General Practice Research Database. (2012)
Bhaskaran, Krishnan; Douglas, Ian; Evans, Stephen; van Staa, Tjeerd; Smeeth, Liam
A Comparison between the Standard Self Controlled Case Series Design and a Modification To Account for Events That Censor the Observation Period. (2012)
Brauer, R; Smeeth, L; Anaya-Izquierdo, K; Farrington, CP; Whitaker, H; Douglas, I
Clopidogrel and interaction with proton pump inhibitors: comparison between cohort and within person study designs. (2012)
Douglas, Ian J; Evans, Stephen JW; Hingorani, Aroon D; Grosso, Anthony M; Timmis, Adam; Hemingway, Harry; Smeeth, Liam
2011
How Long Do Children Stay on Antiepileptic Treatments in the UK? (2011)
Beau, R; Douglas, I; Evans, S; Clayton, T; Smeeth, L
Comparison of Retention Rates of First Line Antiepileptic Drugs in Children in the UK. (2011)
Beau, R; Douglas, I; Stephen, E; Clayton, T; Smeeth, L
The Risk of Cancer Associated with Angiotensin-II Receptor Blockers. (2011)
Bhaskaran, K; Douglas, I; Evans, S; van Staa, T; Smeeth, L
Using the Self Controlled Case Series Method To Assess the Risk of Myocardial Infarction in GPRD-Registered Users of Antipsychotic Agents. (2011)
Brauer, R; Douglas, I; Smeeth, L
The association between antipsychotic agents and the risk of myocardial infarction: a systematic review. (2011)
Brauer, Ruth; Douglas, Ian; Smeeth, Liam
A Cohort Study Using GPRD and MINAP Data To Investigate the Possible Drug Interaction between Clopidogrel and Cytochrome P450 2C19 Inhibitors. (2011)
Douglas, I; Smeeth, L; Hingorani, A; Grosso, A; Evans, S
Effect of statin treatment on short term mortality after pneumonia episode: cohort study. (2011)
Douglas, Ian; Evans, Stephen; Smeeth, Liam
The use of antidepressants and the risk of haemorrhagic stroke: a nested case control study. (2011)
Douglas, Ian; Smeeth, Liam; Irvine, David
Self-Controlled Case Series Analysis With Event-Dependent Observation Periods. (2011)
Farrington, C Paddy; Anaya-Izquierdo, Karim; Whitaker, Heather J; Hocine, Mounia N; Douglas, Ian; Smeeth, Liam
Use of the self-controlled case series method in drug safety assessment. (2011)
Grosso, Anthony; Douglas, Ian; MacAllister, Raymond; Petersen, Irene; Smeeth, Liam; Hingorani, Aroon D
Abstracts of the 27th International Conference on Pharmacoepidemiology & Therapeutic Risk Management. Chicago, Illinois, USA. August 14-17, 2011. (2011)
Langham, Julia; Douglas, Ian; Brauer, Ruth; Bhaskaran, Krishnan; Smeeth, Liam
Cutting feedback in Bayesian regression adjustment for the propensity score. (2011)
McCandless, Lawrence C; Douglas, Ian J; Evans, Stephen J; Smeeth, Liam
2009
The risk of fractures associated with thiazolidinediones: a self-controlled case-series study. (2009)
Douglas, Ian J; Evans, Stephen J; Pocock, Stuart; Smeeth, Liam
Inhaled tiotropium bromide and risk of stroke. (2009)
Grosso, Anthony; Douglas, Ian; Hingorani, Aroon D; MacAllister, Raymond; Hubbard, Richard; Smeeth, Liam
Oral bisphosphonates and risk of atrial fibrillation and flutter in women: a self-controlled case-series safety analysis. (2009)
Grosso, Anthony; Douglas, Ian; Hingorani, Aroon; MacAllister, Raymond; Smeeth, Liam
THE APPLICATION OF DISCRETE EVENT SIMULATION TO QUANTITATIVE RISK BENEFIT ANALYSIS. (2009)
Maguire, A; Douglas, I; Blak, BT
Effect of statins on a wide range of health outcomes: a cohort study validated by comparison with randomized trials. (2009)
Smeeth, Liam; Douglas, Ian; Hall, Andrew J; Hubbard, Richard; Evans, Stephen
2008
Exposure to antipsychotics and risk of stroke: self controlled case series study. (2008)
Douglas, Ian J; Smeeth, Liam
Post-marketing assessment of the safety of strontium ranelate; a novel case-only approach to the early detection of adverse drug reactions. (2008)
Grosso, Anthony; Douglas, Ian; Hingorani, Aroon; MacAllister, Raymond; Smeeth, Liam
Age-related macular degeneration and complement activation-related diseases: a population-based case-control study. (2008)
Nitsch, Dorothea; Douglas, Ian; Smeeth, Liam; Fletcher, Astrid
2007
A propensity score controlled cohort study to investigate the effects of statins. (2007)
Douglas, IJ; Smeeth, L; Evans, SJ
A case-control study of drug risk factors for age-related macular degeneration. (2007)
Douglas, Ian J; Cook, Claire; Chakravarthy, Usha; Hubbard, Richard; Fletcher, Astrid E; Smeeth, Liam
Patterns of cholesterol levels in patients treated with lipid lowering drugs in UK primary care. (2007)
Maguire, A; Douglas, I; Smeeth, L
Determinants of cholesterol and triglycerides recording in patients treated with lipid lowering therapy in UK primary care. (2007)
Maguire, A; Douglas, I; Smeeth, L; Thompson, M
Classification of hyperlipidemia from automated primary care data in the UK and France. (2007)
Maguire, A; Schwalm, MS; Douglas, I; Smeeth, L